U 93385
U93385 is a 5-HT₁A receptor agonist. U93385 exhibits no significant α₂ adrenergic, D₂ dopamine, or other receptor activities. U93385 has a heart rate regulating effect, stimulating the vagus nerve to induce bradycardia. U93385 can be used to study the 5-HT₁A receptor-mediated vagal nerve tolerance mechanism.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 147145-16-2
- 分子式: C16H22N2O
- 分子量:258.36
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
5-HT Receptor アイソフォーム固有の製品をすべて表示
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生物活性
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5-HT1A Receptor |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Spinal cord transection model established in cats (2.5-4 kg)[1]
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Dosage:0.3, 1.0, 3.0 mg/kg (single dose); 0.01, 0.03, 0.1, 0.3, 1.0, 3.0 mg/kg (cumulative dose); 1 mg/kg (infusion)
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Administration:Intravenous injection (i.v.), single dose, cumulative administration or intravenous infusion
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Result:Dose-dependently reduced bradycardia and arterial blood pressure at single dose.
Failed to lower heart rate in animals pretreated in this cumulative manner.
化学情報
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CAS 番号 147145-16-2
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分子量 258.36
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分子式 C16H22N2O
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SMILES
NC(C1=C2[C@@]3([H])[C@](CCC2=CC=C1)([H])N(CCC)CC3)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
U 93385 関連分類
HY-106928 関連分類
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