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Cat. No.: HY-125720

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A-39183A

A-39183A is an antibiotic that shows significant cytotoxicity to HeLa cells, with an IC₅₀ value of 1.8 μM.

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CAS No.: 79426-51-0
화학식: C₃₄H₃₀O₁₀
분자량:598.60

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (279 KB)

A-39183A Chemical Structure

CAS No.: 79426-51-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
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Calculators
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Bioz

Biological Activity

제품 설명

A-39183A is an antibiotic that shows significant cytotoxicity to HeLa cells, with an IC₅₀ value of 1.8 μM^[1].

All Antibiotic Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HCT-116	IC₅₀	>10 μM Compound: 2; A-39183A	Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability after 48 hrs by SRB assay Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability after 48 hrs by SRB assay	[PMID: 32880456]
HeLa	IC₅₀	1.8 μM Compound: 2; A-39183A	Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 48 hrs by SRB assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 48 hrs by SRB assay	[PMID: 32880456]
HL-60	IC₅₀	>10 μM Compound: 2; A-39183A	Cytotoxicity against human HL-60 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human HL-60 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 32880456]
K562	IC₅₀	5.1 μM Compound: 2; A-39183A	Cytotoxicity against human K562 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human K562 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 32880456]

Chemical Information

CAS No. 79426-51-0
분자량 598.60
화학식 C₃₄H₃₀O₁₀
SMILES

O=C1C[C@](C)(O)[C@@H](C(C)=O)C2=C1C(O)=C3C(O)=CC=CC3=C2C4=C5C=CC=C(O)C5=C(O)C6=C4[C@H](C(C)=O)[C@@](C)(O)CC6=O
Structure Classification
- Antibiotics
- Other Antibiotics
Initial Source
- Microorganisms
Streptomyces fumigatiscleroticus
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (279 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Junxiao Wang, et al. Dimeric Tetrahydroanthracene Regioisomers and Their Monomeric Precursor Produced by Streptomyces fumigatiscleroticus HDN10255. J Nat Prod. 2020 Sep 25;83(9):2797-2802. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

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A-39183A

All Antibiotic Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

A-39183A Related Classifications

HY-125720 Related Classifications