Ageconyflavone C
Ageconyflavone C is a natural pentamethoxyflavonoid found in the aerial parts of Ageratum conyzoides L. Ageconyflavone C inhibits Trypanosoma brucei rhodesiense, Leishmania donovani, and Chloroquine (HY-17589A)- and Pyrimethamine (HY-18062)-resistant Plasmodium falciparum K1, with IC50 values of 7.8, 9.2, and 9.25 μM, respectively. Ageconyflavone C can be used in studies related to anti-protozoal and parasitic infection research.
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- CAS No.: 93124-90-4
- 화학식: C20H20O8
- 분자량:388.37
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Parasite Isoforms
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Biological Activity
Ageconyflavone C (compound 5) (>30 μg/mL; >90 μg/mL) exhibits moderate in vitro antiprotozoal activity against Trypanosoma brucei rhodesiense (IC50 = 7.8 μM), Leishmania donovani (IC50 = 9.2 μM), and Plasmodium falciparum (IC50 = 9.25 μM), with no activity against Trypanosoma cruzi and no cytotoxicity against L6 rat skeletal myoblasts at the highest tested concentrations[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 93124-90-4
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분자량 388.37
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화학식 C20H20O8
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SMILES
O=C1C=C(C2=CC(OC)=C(O)C(OC)=C2)OC3=C1C(OC)=C(OC)C(OC)=C3
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)