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Cat. No.: HY-180533

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Aldoview

AldoView (Compound 3) is an intermediate. AldoView can be labeled with fluorine-18 to synthesize [¹⁸F]AldoView. [¹⁸F]AldoView is a highly selective aldosterone synthase PET imaging agent. AldoView can be used in imaging studies of primary aldosteronism.

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CAS No.: 1356479-94-1
화학식: C₁₅H₁₀F₃N₃
분자량:289.26

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Aldoview Chemical Structure

CAS No.: 1356479-94-1

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One-stop CDMO Service

One-Stop Platform：From Independent R&D to Pilot-Scale Production

Biological Activity
- 제품 설명
- IC₅₀ & Target
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target

Aldosterone Synthase

All Radionuclide-Drug Conjugates (RDCs) Isoforms :

All Cytochrome P450 Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
COS-7	IC₅₀	10000 nM Compound: 26	Inhibition of human CYP17 expressed in COS7 cells incubated for 1 hr before 17-hydroxypregnenolone substrate addition by EIA method Inhibition of human CYP17 expressed in COS7 cells incubated for 1 hr before 17-hydroxypregnenolone substrate addition by EIA method	[PMID: 26005536]

Chemical Information

CAS No. 1356479-94-1
분자량 289.26
화학식 C₁₅H₁₀F₃N₃
SMILES

FC1=CC(C2=NC3=C(N2C4CC4)C=C(F)C(F)=C3)=CN=C1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Sander K, et al. Development of [18F]AldoView as the First Highly Selective Aldosterone Synthase PET Tracer for Imaging of Primary Hyperaldosteronism. J Med Chem. 2021 Jul 8;64(13):9321-9329. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
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수량:
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Aldoview

All Radionuclide-Drug Conjugates (RDCs) Isoforms

All Cytochrome P450 Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Aldoview Related Classifications

HY-180533 Related Classifications