Asterric Acid
Asterric acid is an antibiotic fungal metabolite that completely inhibits the binding of the potent vasoconstrictor endothelin (ET)-1 to the ETA receptor in A10 cells at 0.1 μM.1 Asterric acid derivatives have also been shown to inhibit VEGF-induced tube formation of human umbilical vein endothelial cells at 3-10 μM, which suggests its usefulness as an antiangiogenic agent.
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- CAS No.: 577-64-0
- 화학식: C17H16O8
- 분자량:348.30
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Biological Activity
제품 설명
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A10 | IC50 |
1 x 10-5 M
Compound: 3
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Displacement of endothelin-1 from ETA receptor in rat A10 cells
Displacement of endothelin-1 from ETA receptor in rat A10 cells
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[PMID: 11809055] |
Chemical Information
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CAS No. 577-64-0
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분자량 348.30
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화학식 C17H16O8
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SMILES
CC1=CC(O)=C(C(OC2=C(C=C(C=C2C(OC)=O)O)OC)=C1)C(O)=O
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Synonyms
Dimethylosoic acid; RES-1214-1; TAN 1415A
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Asterric Acid Related Classifications
HY-119843 Related Classifications
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