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Cat. No.: HY-124199

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Cephalochromin

Cephalochromin is an antibiotic and an inhibitor for bacterial fatty acid synthase (FabI). Cephalochromin inhibits FabI of Staphylococcus aureus and Escherichia coli with IC₅₀ of 1.9 and 1.8 μM. Cephalochromin inhibits gram-positive methicillin-resistant S. aureus (MRSA) and quinolone-resistant S. aureus (QRSA), with MIC of 2-8 µg/mL.

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CAS No.: 25908-26-3
화학식: C₂₈H₂₂O₁₀
분자량:518.47

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (278 KB)

Cephalochromin Chemical Structure

CAS No.: 25908-26-3

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

All Antibiotic Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	2.72 μM Compound: Cephalochromin	Cytotoxicity against human A549 cells after 48 hrs by SRB assay Cytotoxicity against human A549 cells after 48 hrs by SRB assay	[PMID: 24588135]
A549	IC₅₀	5.22 μM Compound: Cephalochromin	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 24588135]
BHK-21	IC₅₀	20 μM Compound: Cephalochromin	Antagonist activity at human glucagon receptor expressed in BHK21 cells assessed as inhibition of glucagon-induced cAMP elevation by RIA Antagonist activity at human glucagon receptor expressed in BHK21 cells assessed as inhibition of glucagon-induced cAMP elevation by RIA	[PMID: 15387654]
Caco-2	IC₅₀	12.4 μM Compound: Cephalochromin	Cytotoxicity against human Caco2 cells after 48 hrs by MTT assay Cytotoxicity against human Caco2 cells after 48 hrs by MTT assay	[PMID: 24588135]
Hep 3B2	IC₅₀	14.31 μM Compound: Cephalochromin	Cytotoxicity against human Hep3B cells after 48 hrs by MTT assay Cytotoxicity against human Hep3B cells after 48 hrs by MTT assay	[PMID: 24588135]
HT-1080	IC₅₀	4.98 μM Compound: Cephalochromin	Cytotoxicity against human HT1080 cells after 48 hrs by MTT assay Cytotoxicity against human HT1080 cells after 48 hrs by MTT assay	[PMID: 24588135]
Huh-7	IC₅₀	4.64 μM Compound: Cephalochromin	Cytotoxicity against human HuH7 cells after 48 hrs by MTT assay Cytotoxicity against human HuH7 cells after 48 hrs by MTT assay	[PMID: 24588135]
SW1353	IC₅₀	3.54 μM Compound: Cephalochromin	Cytotoxicity against human SW1353 cells after 48 hrs by MTT assay Cytotoxicity against human SW1353 cells after 48 hrs by MTT assay	[PMID: 24588135]

Chemical Information

CAS No. 25908-26-3
분자량 518.47
화학식 C₂₈H₂₂O₁₀
SMILES

OC(C(C(C=C1O[C@@H](C2)C)=[C@@](C(O)=C3)[C@@](C(O)=C4)=C(C=C5O[C@@H](C6)C)C(C(O)=C5C6=O)=C4O)=C3O)=C1C2=O
Structure Classification
- Antibiotics
- Other Antibiotics
Initial Source
- Microorganisms
Cephalosporium caerulens
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (278 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zheng CJ, et al., Cephalochromin, a FabI-directed antibacterial of microbial origin. Biochem Biophys Res Commun. 2007 Nov 3;362(4):1107-12. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

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Cephalochromin

All Antibiotic Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Cephalochromin Related Classifications

HY-124199 Related Classifications