country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-172981

Copy Link Print Information

CTW0404

CTW0404 is a 5-HT_2AR positive allosteric modulator that enhances Serotonin (HY-B1473A)-induced intracellular calcium release without intrinsic agonist activity. CTW0404 attenuates head-twitch responses but does not induce head twitches by itself. CTW0404 can be used for research on neuropsychiatric disorders.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 2913202-87-4
화학식: C₂₁H₃₃N₃O₂
분자량:359.51

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

CTW0404 Chemical Structure

CAS No.: 2913202-87-4

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
- In Vivo
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target

^[1]

5-HT_2A Receptor

All 5-HT Receptor Isoforms :

In Vitro

CTW0404 acts as a 5-HT_2AR PAM in h5-HT_2AR-expressing stable cell lines, enhancing 5-HT-induced intracellular calcium release without intrinsic agonist activity and lacking activity at h5-HT_2BR and h5-HT_2CR^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

CTW0404 does not produce (-)-DOI-like interoceptive effects in rats^[1].
CTW0404 lacks head-twitch-inducing activity and attenuates (-)-DOI-evoked head twitches in rats^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

CAS No. 2913202-87-4
분자량 359.51
화학식 C₂₁H₃₃N₃O₂
SMILES

O=C(C1CC(CCN1)CCC2=CC=CC=C2)NCCCN3CCOCC3
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zamora J C, et al. Serendipitous Discovery of Novel 5-HT2AR Positive Allosteric Modulators (PAMs) Derived From 5-HT2CR PAM Scaffolds[J]. The Journal of Pharmacology and Experimental Therapeutics, 2024, 389: 87.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

견적 받기 해외재고보유

Other size

견적 받기