Flumezapine
Flumezapine (LY 120363) is a potent and balanced antagonist of the dopamine D2 receptor and the 5-hydroxytryptamine receptor (5-HT receptor). Flumezapine does not alter the increase in serum cortisol caused by κ-opioid receptor agonists. Flumezapine inhibits the conditioned avoidance response in rats and has a low risk of extrapyramidal side effects. Flumezapine can be used in antipsychotic research.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 61325-80-2
- 화학식: C17H19FN4S
- 분자량:330.42
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 61325-80-2
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분자량 330.42
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화학식 C17H19FN4S
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SMILES
FC1=CC2=C(NC3=C(C(N4CCN(CC4)C)=N2)C=C(C)S3)C=C1
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Synonyms
LY 120363
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Fuller RW, Mason NR. Flumezapine, an antagonist of central dopamine and serotonin receptors. Res Commun Chem Pathol Pharmacol. 1986 Oct;54(1):23-34. [Content Brief]
[2]. Fuller RW, Snoddy HD. Flumezapine and zotepine: 5-hydroxytryptamine antagonism not involved in the lack of synergism of these antipsychotic drugs with amfonelic acid in rats. J Pharm Pharmacol. 1985 Oct;37(10):755-6. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Flumezapine Related Classifications
HY-106605 Related Classifications
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