Glidobactin A
Glidobactin A is an acyl peptide antibiotic. Glidobactin A has activity against Candida, Aspergillus fumigatus and Trichophyton, but it is not effective against Candida albicans M-9 infection in mice.
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- CAS No.: 108351-50-4
- 화학식: C27H44N4O6
- 분자량:520.66
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Antibiotic Isoforms
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
33.3 nM
Compound: glidobactin A
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Cytotoxicity against human HCT116 cells assessed as cell viability after 5 days by MTT assay relative to control
Cytotoxicity against human HCT116 cells assessed as cell viability after 5 days by MTT assay relative to control
|
[PMID: 22909174] |
| MIA PaCa-2 | IC50 |
0.069 μM
Compound: 1
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Inhibition of 20S proteasome in human MIAPaCa2 cells after 90 mins by fluorescence-based colorimetry
Inhibition of 20S proteasome in human MIAPaCa2 cells after 90 mins by fluorescence-based colorimetry
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[PMID: 23095088] |
| MIA PaCa-2 | IC50 |
7 x 10-3 μM
Compound: 1
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Cytotoxicity against human MIAPaCa2 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human MIAPaCa2 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 23095088] |
| MIA PaCa-2 | IC50 |
7 nM
Compound: 1
|
Cytotoxicity against human MIAPaCa2 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human MIAPaCa2 cells assessed as reduction in cell viability after 72 hrs by MTT assay
|
[PMID: 23095088] |
Chemical Information
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CAS No. 108351-50-4
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분자량 520.66
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화학식 C27H44N4O6
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SMILES
CCCCCCC/C=C/C=C/C(N[C@H](C(N[C@@H]1C(N[C@@H](C)/C=C/C(NCC[C@H](O)C1)=O)=O)=O)[C@H](O)C)=O
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)