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Cat. No.: HY-183994

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HL82624

HL82624 is a CXCR4 agnoist. HL82624 triggers CXCR4-mediated cell migration. HL82624 can be used for the research of neurodegenerative diseases.

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화학식: C₃₃H₅₁N₁₁O₄
분자량:665.83

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

HL82624 Chemical Structure

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

HL82624 is a CXCR4 agnoist. HL82624 triggers CXCR4-mediated cell migration. HL82624 can be used for the research of neurodegenerative diseases^[1].

IC₅₀ & Target^[1]

CXCR4

All CXCR Isoforms :

In Vitro

HL82624 reduces CXCR4 activation energy barriers for all transition states, and facilitates early-stage CXCR4 activation^[1].
HL82624 binds to CXCR4 on Sup-T1 cells with an IC₅₀ of 24 μM^[1].
HL82624 (1-100 μM; 3 h) promotes CXCR4-mediated cell migration in Sup-T1 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Migration Assay ^[1]

Cell Line:

Sup-T1 cells
Concentration:

1; 10; 50; 100 μM
Incubation Time:

3 h
Result:

Showed maximal activity observed at 10-50 μM.
Promoted CXCR4-mediated cell migration.

Chemical Information

분자량 665.83
화학식 C₃₃H₅₁N₁₁O₄
SMILES

NC(NCCC[C@H](NCC1=CC=CC=N1)C(NCC2=CC(C[C@H](NC([C@H]3N(C([C@@H](N)CCCCN)=O)CCC3)=O)C(N)=O)=CC=C2)=O)=N
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Zhou J, et al. Computational Insights into the Activation Mechanism of CXCR4: Implications for the Design of Small Molecule Agonists. J Am Chem Soc. 2026;148(20):20545-20554. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Other size

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

HL82624

All CXCR Isoforms