Ikarugamycin
Based on 2 publication(s) in Google Scholar
Ikarugamycin is an antibiotic and a inhibitor of clathrin-mediated endocytosis (CME).
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 99.9%
- CAS No.: 36531-78-9
- 화학식: C29H38N2O4
- 분자량:478.62
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보관:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Publications Citing Use of MedChemExpress (MCE) Ikarugamycin
MoreAll Antibiotic Isoforms
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Biological Activity
Clathrin-mediated endocytosis[1]
Ikarugamycin has an IC50 of 2.7 μM in H1299 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 36531-78-9
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Appearance Solid
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분자량 478.62
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화학식 C29H38N2O4
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Color White to light yellow
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SMILES
O=C(/C=C/[C@@H]1C[C@]2([C@@]([H])([C@H]1C/C=C\3)C=C[C@@]4([C@@]2(C[C@H]([C@H]4CC)C)[H])[H])[H])C5=C([C@@H](NC5=O)CCCNC3=O)O
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Structure Classification
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Initial Source
Streptomyces species
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (2)
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Journal Impact Factor
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Most Recent
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J Extracell Vesicles
2021 Jan;10(3):e12051. PMID: 33473262 -
J Immunother Cancer
Anticancer effects of ikarugamycin and astemizole identified in a screen for stimulators of cellular immune responses. [Abstract]2023 Jul;11(7):e006785. PMID: 37419511
순도&문서
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Data Sheet (274 KB)
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SDS (419 KB)
- English - EN (419 KB)
- Français - FR (419 KB)
- Deutsch - DE (419 KB)
- Norwegian - NO (419 KB)
- Español - ES (419 KB)
- Swedish - SV (419 KB)
- Italian - IT (419 KB)
- Korean - KR (419 KB)
- Portuguese - PT (419 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)