L-738167
L-738167 is an orally active fibrogen receptor antagonist that prevents the binding of fibrinogen to GP IIb/IIIa. L-738167 can be utilized in thrombus research.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 163212-43-9
- 화학식: C25H34N6O6S
- 분자량:546.64
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HUVEC | IC50 |
>3 nM
Compound: 5
|
Inhibition of human umbilical vein endothelial cells (HUVEC) attachment to fibrinogen (FG)
Inhibition of human umbilical vein endothelial cells (HUVEC) attachment to fibrinogen (FG)
|
[PMID: 9191954] |
| HUVEC | IC50 |
>3 nM
Compound: 5
|
Inhibition of human umbilical vein endothelial cells (HUVEC) attachment to fibronectin
Inhibition of human umbilical vein endothelial cells (HUVEC) attachment to fibronectin
|
[PMID: 9191954] |
| HUVEC | IC50 |
>3 nM
Compound: 5
|
Inhibition of human umbilical vein endothelial cells (HUVEC) attachment to vitronectin (VN)
Inhibition of human umbilical vein endothelial cells (HUVEC) attachment to vitronectin (VN)
|
[PMID: 9191954] |
Chemical Information
-
CAS No. 163212-43-9
-
분자량 546.64
-
화학식 C25H34N6O6S
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SMILES
O=C(O)[C@H](CNC(C1=NN2C(C(N(CCC3CCNCC3)CCC2)=O)=C1)=O)NS(=O)(C4=CC=C(C)C=C4)=O
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선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)