Lubiprostone-d7
Lubiprostone-d7 (RU-0211-d7) is the deuterium labeled Lubiprostone. Lubiprostone (SPI-0211) increases intestinal fluid secretion through generation of CIC-2/CFTR and activation of cAMP signaling pathway. Lubiprostone inhibits myeloperoxidase (MPO) activity, downregulates Indomethacin (HY-14397)-induced iNOS and TNFα expression. Lubiprostone can be used for chronic constipation research.
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- CAS No.: 1217675-13-2
- 화학식: C20H25D7F2O5
- 분자량:397.51
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1217675-13-2
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Unlabeled Cas 136790-76-6
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분자량 397.51
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화학식 C20H25D7F2O5
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SMILES
C(CC(C(CC(C(C([2H])([2H])[2H])([2H])[2H])([2H])[2H])(F)F)=O)[C@@H]1[C@@H](CCCCCCC(O)=O)C(=O)C[C@H]1O
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Synonyms
RU-0211-d7; SPI-0211-d7
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Lubiprostone-d7 Related Classifications
HY-B0679S Related Classifications
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