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Cat. No.: HY-180960

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NEP202

NEP202 is a SMARCA2 PROTAC degrader designed based on the GID4 E3 ligase. NEP168 can be used for cancer research.
(Pink: SMARCA2 ligand (HY-46618); Blue: Ligands for E3 Ligase ligand (HY-D2259); Black: linker).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 3031840-41-9
화학식: C₄₆H₅₇N₁₁O₆
분자량:860.01

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

NEP202 Chemical Structure

CAS No.: 3031840-41-9

사이즈

가격

재고

수량

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

NEP202 is a SMARCA2 PROTAC degrader designed based on the GID4 E3 ligase. NEP168 can be used for cancer research^[1]. (Pink: SMARCA2 ligand (HY-46618); Blue: Ligands for E3 Ligase ligand (HY-D2259); Black: linker).

IC₅₀ & Target^[1]

SMARCA2

All PROTACs Isoforms :

All SWI/SNF Complex Isoforms :

Chemical Information

CAS No. 3031840-41-9
분자량 860.01
화학식 C₄₆H₅₇N₁₁O₆
SMILES

O=C(CNCC1=CC2=CC=CC=C2N1)N[C@H]3CC[C@H](CC3)C(NC4=C5)=NC4=CC=C5OCCOCCOCCNC(CN6CCN(C7=C(N)N=NC(C8=C(C=CC=C8)O)=C7)CC6)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Li Y, et al. Design of PROTACs utilizing the E3 ligase GID4 for targeted protein degradation. Nature Structural & Molecular Biology. 2025 Apr 28:1-3.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
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Purity:
수량:

NEP202

All PROTACs Isoforms

All SWI/SNF Complex Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

NEP202 Related Classifications

HY-180960 Related Classifications