Palmitic acid-d5
Based on 1 Customer Validation
Palmitic acid-d5 is the deuterium labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells.
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- Purity: 99.31%
- CAS No.: 1219802-61-5
- 화학식: C16H27D5O2
- 분자량:261.45
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보관:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All Endogenous Metabolite Isoforms
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Biological Activity
제품 설명
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
신청
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1219802-61-5
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Unlabeled CAS 57-10-3
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Appearance Solid
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분자량 261.45
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화학식 C16H27D5O2
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Color White to off-white
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SMILES
[2H]C([2H])([2H])CCCCCCCCCCCCCC([2H])([2H])C(O)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
용액&용해도
In Vitro:
DMSO : 50 mg/mL (191.24 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Harada H, et al. Antitumor activity of palmitic acid found as a selective cytotoxic substance in a marine red alga. Anticancer Res. 2002 Sep-Oct;22(5):2587-90. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.8248 mL | 19.1241 mL | 38.2482 mL | 95.6206 mL |
| 5 mM | 0.7650 mL | 3.8248 mL | 7.6496 mL | 19.1241 mL | |
| 10 mM | 0.3825 mL | 1.9124 mL | 3.8248 mL | 9.5621 mL | |
| 15 mM | 0.2550 mL | 1.2749 mL | 2.5499 mL | 6.3747 mL | |
| 20 mM | 0.1912 mL | 0.9562 mL | 1.9124 mL | 4.7810 mL | |
| 25 mM | 0.1530 mL | 0.7650 mL | 1.5299 mL | 3.8248 mL | |
| 30 mM | 0.1275 mL | 0.6375 mL | 1.2749 mL | 3.1874 mL | |
| 40 mM | 0.0956 mL | 0.4781 mL | 0.9562 mL | 2.3905 mL | |
| 50 mM | 0.0765 mL | 0.3825 mL | 0.7650 mL | 1.9124 mL | |
| 60 mM | 0.0637 mL | 0.3187 mL | 0.6375 mL | 1.5937 mL | |
| 80 mM | 0.0478 mL | 0.2391 mL | 0.4781 mL | 1.1953 mL | |
| 100 mM | 0.0382 mL | 0.1912 mL | 0.3825 mL | 0.9562 mL |