PD 158771
PD 158771 is an antipsychotic agent that functions as a partial agonist for D2 /D3 receptors (Ki = 42.0/13.7 nM) and as an agonist for 5-HT1A receptors (Ki = 2.6 nM). PD 158771 can be utilized in antipsychotic research.
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- CAS No.: 189152-50-9
- 화학식: C22H31N5
- 분자량:365.52
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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hD2 Receptor 42 nM (Ki) |
5-HT1A Receptor |
Human D3 Receptor 13.7 nM (Ki) |
human 5-HT1A Receptor 2.6 nM (Ki) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO-K1 | EC50 |
29 nM
Compound: 14
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The in vitro intrinsic activity was measured at DA D2 receptor by measuring its ability to increase [3H]thymidine uptake in CHO-K1 cells transfected with the Dopamine receptor D2
The in vitro intrinsic activity was measured at DA D2 receptor by measuring its ability to increase [3H]thymidine uptake in CHO-K1 cells transfected with the Dopamine receptor D2
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[PMID: 9513604] |
Chemical Information
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CAS No. 189152-50-9
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분자량 365.52
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화학식 C22H31N5
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SMILES
C1(N[C@H]2CC[C@H](CCN3CCN(C4=CC=CC=C4)CC3)CC2)=NC=CC=N1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PD 158771 Related Classifications
HY-167648 Related Classifications
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