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Propranolol

50 Cited Publications
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Based on 50 publication(s) in Google Scholar

Propranolol is a nonselective and BBB-permeable β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively. Propranolol inhibits [3H]-DHA binding to rat brain membrane preparation with an IC50 of 12 nM. Propranolol is used for the study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy.

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  • Purity: 99.91%
  • CAS No.: 525-66-6
  • 화학식: C16H21NO2
  • 분자량:259.34
  • 보관:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 1 year , -20°C, 6 months
  • Propranolol Chemical Structure
    Propranolol Chemical Structure
  • Experimental Validation Results for Propranolol
  • Experimental Validation Results for Propranolol
  • Experimental Validation Results for Propranolol
  • Experimental Validation Results for Propranolol
  • Experimental Validation Results for Propranolol
CAS No.: 525-66-6
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  • Propranolol Chemical Structure
    Propranolol Chemical Structure
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  • 1/16

    Propranolol purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Oct 6:e04817. [Abstract]

    Customer Validation
     Propranolol (2 mg/kg; ip; 21 days). Quantitative of sperm density in the cauda epididymis.

  • 1/16

    Propranolol purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Oct 6:e04817. [Abstract]

    Customer Validation
     Propranolol (2 mg/kg; ip; 21 days). Western blot of SOX9 expression across four experimental groups.

  • 1/16

    Propranolol purchased from MedChemExpress. Usage Cited in: Bone Res. 2024 Mar 21;12(1):18. [Abstract]

    Customer Validation
     Representative μCT images of femurs from OVX, OVX + Fx (fracture), and OVX + Fx mice treated with Pro (Propranolol; 0.5 g/L; 4 weeks), PTH or PTH + Pro.

  • 1/16

    Propranolol purchased from MedChemExpress. Usage Cited in: Bone Res. 2024 Mar 21;12(1):18. [Abstract]

    Customer Validation
     Representative images of co-localization of Bmal1 (green) and OCN (red) immunofluorescent staining in distal femurs from OVX, OVX + Fx, and OVX + Fx mice treated with Pro (Propranolol; 0.5 g/L; 4 weeks), PTH or PTH + Pro.

  • 1/16

    Propranolol purchased from MedChemExpress. Usage Cited in: Nat Commun. 2023 May 2;14(1):2523. [Abstract]

    Customer Validation
     Mice received PBS or Propranolol (5 mg/kg) 30 mins before the injection of PBS or 1 mg/kg BK for 15 mins in the absence of food and water at 25 °C. Rectal temperature at different time point.

  • Propranolol