Pyrantel
Based on 2 publication(s) in Google Scholar
Pyrantel is an orally active antiparasitic agent. Pyrantel induces spastic paralysis in parasites via actions on neural and muscular cholinergic receptors as a nicotinic acetylcholine receptor (nAChR) agonist. Pyrantel eliminates both immature and mature endoparasites in horses. Pyrantel can be used in research related to parasitic infections.
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- CAS No.: 15686-83-6
- 화학식: C11H14N2S
- 분자량:206.31
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보관:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Other In-stock Forms of Pyrantel
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Pyrantel
MoreAll Parasite Isoforms
More
Biological Activity
제품 설명
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 15686-83-6
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Appearance Solid
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분자량 206.31
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화학식 C11H14N2S
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Color White to off-white
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SMILES
CN1CCCN=C1/C=C/C2=CC=CS2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (2)
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Journal Impact Factor
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Most Recent
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Eur J Med Chem
2024 Dec 5:279:116842. PMID: 39260319 -
순도&문서
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Data Sheet (282 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Tritten L, et al. In vitro and in vivo efficacy of Monepantel (AAD 1566) against laboratory models of human intestinal nematode infections. PLoS neglected tropical diseases. 2011 Dec;5(12):e1457. [Content Brief]
[2]. Martin RJ, et al. Oxantel is an N-type (methyridine and nicotine) agonist not an L-type (levamisole and pyrantel) agonist: classification of cholinergic anthelmintics in Ascaris. International journal for parasitology. 2004 Aug;34(9):1083-90. [Content Brief]
[3]. Lyons ET, et al. Critical test of three salts of pyrantel against internal parasites of the horse. Am J Vet Res. 1974 Dec;35(12):1515-22. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pyrantel Related Classifications
HY-12641A Related Classifications
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Keywords
- Pyrantel
- 15686-83-6
- Parasite
- nAChR
- Nicotinic acetylcholine receptors
- Parascaris equorum
- equine internal parasites
- small strongyles
- L-subtype cholinergic receptors
- nematodes
- intestinal nematode infections
- equine internal parasitic infections
- Draschia megastoma
- Ascaris suum
- Strongylus vulgaris
- Inhibitor
- inhibitor
- inhibit