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Cat. No.: HY-W1009348

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RR-11055

RR-11055 (Compound 8) is a ligand for E3 ligase, that exhibits an affinity with cereblon with K_i of 0.38 μM. RR-11055 can be used for synthesis of PROTAC Degrader ERD-1233 (HY-169367).

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CAS No.: 3026009-09-3
화학식: C₁₈H₂₀N₄O₄
분자량:356.38

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

RR-11055 Chemical Structure

CAS No.: 3026009-09-3

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
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Biological Activity

제품 설명

RR-11055 (Compound 8) is a ligand for E3 ligase, that exhibits an affinity with cereblon with K_i of 0.38 μM. RR-11055 can be used for synthesis of PROTAC Degrader ERD-1233 (HY-169367)^[1].

IC₅₀ & Target

Cereblon

All Ligands for E3 Ligase Isoforms :

Chemical Information

CAS No. 3026009-09-3
분자량 356.38
화학식 C₁₈H₂₀N₄O₄
SMILES

O=C1C2=CC=C(N3[C@@](CNCC3)([H])CO4)C4=C2CN1[C@@H]5C(NC(CC5)=O)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Acharyya RK, et al., Discovery of ERD-1233 as a Potent and Orally Efficacious Estrogen Receptor PROTAC Degrader for the Treatment of ER+ Human Breast Cancer. J Med Chem. 2024 Nov 14;67(21):19010-19037. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
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수량:
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RR-11055

All Ligands for E3 Ligase Isoforms

Biological Activity

제품 설명

IC50 & Target

Chemical Information

순도&문서

References

Calculators

Help & FAQs

RR-11055 Related Classifications

HY-W1009348 Related Classifications

Bioz

Keywords

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