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Cat. No.: HY-124499

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RUC-1

RUC-1 (Compound 1) is an inhibitor for αIIbβ3 integrin. RUC-1 inhibits fibrin deposition and platelet aggregation in hybrid hαIIb/mβ3 receptors expressing mice. RUC-1 exhibits antithrombotic effect in hαIIb/mβ3 receptor expressing mice.

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CAS No.: 796886-30-1
화학식: C₁₁H₁₅N₅OS
분자량:265.33

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

RUC-1 Chemical Structure

CAS No.: 796886-30-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
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Classifications
Bioz

Biological Activity

제품 설명

All Integrin Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
Platelet	IC₅₀	4 μM Compound: 1, RUC-1	Antiplatelet activity in platelet (unknown origin) assessed as inhibition of platelet aggregation Antiplatelet activity in platelet (unknown origin) assessed as inhibition of platelet aggregation	[PMID: 24461295]

Chemical Information

CAS No. 796886-30-1
분자량 265.33
화학식 C₁₁H₁₅N₅OS
SMILES

O=C1C=C(N2CCNCC2)N=C3SC(CC)=NN13
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Blue R, et al., Structural and therapeutic insights from the species specificity and in vivo antithrombotic activity of a novel alphaIIb-specific alphaIIbbeta3 antagonist. Blood. 2009 Jul 2;114(1):195-201. [Content Brief]

Calculators

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Mass Mass

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Molecular Weight Molecular Weight

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Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
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RUC-1

All Integrin Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

RUC-1 Related Classifications

HY-124499 Related Classifications