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Cat. No.: HY-123514

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SNAP8719 free base

SNAP8719 free base is a selective α_1D-adrenoceptor antagonist (pK_i = 8.89). SNAP8719 free base shows affinity for the dopamine D₂-, 5-HT_1A-, and the human clonal α_2a-adrenoceptor, with pK_i values of 5.98, 6.47, and <5.0, respectively. SNAP8719 free base causes a concentration-dependent increase in the twitch response.

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CAS No.: 255893-38-0
화학식: C₂₂H₂₈F₃N₃O₂
분자량:423.47

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

SNAP8719 free base Chemical Structure

CAS No.: 255893-38-0

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target

^[1]

Alpha-1D adrenergic receptor

8.89 (pKi)

D₂ Receptor

5.98 (pKi)

5-HT_1A Receptor

6.47 (pKi)

Alpha-2A adrenergic receptor

<5.0 (pKi)

All Adrenergic Receptor Isoforms :

All Dopamine Receptor Isoforms :

All 5-HT Receptor Isoforms :

Chemical Information

CAS No. 255893-38-0
분자량 423.47
화학식 C₂₂H₂₈F₃N₃O₂
SMILES

O=C(N([C@H](C)CN1CCN(C2=CC(F)=C(F)C=C2F)CC1)C(C3)=O)CC43CCCC4
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Buckner SA, et al. A-315456: a selective alpha(1D)-adrenoceptor antagonist with minimal dopamine D(2) and 5-HT(1A) receptor affinity. Eur J Pharmacol. 2001 Dec 14;433(1):123-7. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
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상품명:
CAS No.:
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SNAP8719 free base

All Adrenergic Receptor Isoforms

All Dopamine Receptor Isoforms

All 5-HT Receptor Isoforms