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Cat. No.: HY-N17756

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Withanolide D

Withanolide D (Compound 2) is a steroidal ester found in Withania somnifera (L.) Dunal, with anticancer activity. Withanolide D can activate the heat-shock factor 1 (HSF1)-dependent stress response. Withanolide D can be used for the research of cancer such as lymphoma.

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CAS No.: 30655-48-2
화학식: C₂₇H₃₆O₆
분자량:456.57

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

Withanolide D Chemical Structure

CAS No.: 30655-48-2

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target^[1]

HSF1

All HSP Isoforms :

In Vitro

Withanolide D exhibits cytotoxicity against various cancer cell lines and shows IC₅₀ values of 324 and 710 nM for CHP-100 and 293T cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 30655-48-2
분자량 456.57
화학식 C₂₇H₃₆O₆
SMILES

C[C@]12[C@@]3([C@H](C=CC2=O)O)[C@](C[C@]4([H])[C@]1([H])CC[C@]5([C@@]4([H])CC[C@]5([H])[C@H]([C@@]6([H])CC(C)=C(C(O6)=O)C)O)C)([H])O3
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
- Microorganisms
Hypogymnia vittata
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wijeratne EMK, et al. Withaferin A and Withanolide D Analogues with Dual Heat-Shock-Inducing and Cytotoxic Activities: Semisynthesis and Biological Evaluation. J Nat Prod. 2018 Apr 27;81(4):825-837. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

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Concentration _(start) Concentration _(start)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

상품명:
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Withanolide D

All HSP Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Withanolide D Related Classifications

HY-N17756 Related Classifications