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Cat. No.: HY-187861

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Zotemtegrast

Name: Zotemtegrast
Brand: MedChemExpress
SKU: HY-187861
Availability: PreOrder

(Synonyms: LY-4268989; MORF-057)

Zotemtegrast (LY-4268989; MORF-057) is an orally active integrin α4β7 antagonist. Zotemtegrast is applicable to research related to inflammatory bowel diseases such as ulcerative colitis and Crohn's disease.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 2640360-52-5
화학식: C₃₅H₄₃F₄N₃O₄
분자량:645.73

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Zotemtegrast Chemical Structure

CAS No.: 2640360-52-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target^[1]

α4β7

All Integrin Isoforms :

In Vitro

Integrin α4β7 is an adhesion molecule on the surface of lymphocytes that mediates the homing of immune cells to the intestinal mucosa and participates in intestinal inflammation and immune responses.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2640360-52-5
분자량 645.73
화학식 C₃₅H₄₃F₄N₃O₄
SMILES

CC1=C(C(C)=CC(C)=C1)C2=CC([C@H](CC(O)=O)NC([C@@H](N3C=C(C(C(F)(F)F)=CC3=O)CCN(C)C)CC(C)C)=O)=C(C(C)=C2)F
Synonyms

LY-4268989; MORF-057
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. WHO Drug Information, Vol. 40, No. 2, 2026

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

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Zotemtegrast

All Integrin Isoforms