Lck-IN-4
Lck-IN-4 (Compound A-1) is a protein tyrosine kinase Lck inhibitor with an IC50 of 2 nM. Lck-IN-4 significantly inhibits YAP tyrosine phosphorylation and activity and induces apoptosis in cholangiocarcinoma CCA cells. Lck-IN-4 is cytotoxic in CCA tumor-derived organoids with elevated YAP activity Lck-IN-4 can be used for cancers like cholangiocarcinoma (CCA) research.
For research use only. We do not sell to patients.
- CAS No.: 1326278-38-9
- Formula: C36H43N7O3
- Molecular Weight:621.77
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 1326278-38-9
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Molecular Weight 621.77
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Formula C36H43N7O3
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SMILES
CC1=NC=CN2C([C@H]3CC[C@H](N4CCN(CC4)C)CC3)=NC(C5=CC(OC)=C(C=C5)NC(C6=CC7=C(OC)C=CC=C7N6C)=O)=C12
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Lck-IN-4 Related Classifications
HY-178120 Related Classifications
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