PARP1-IN-42
PARP1-IN-42 (Example 43 cis-a) is a PARP1 inhibitor with IC50 <10 nM. PARP1-IN-42 can be used in cancer research.
For research use only. We do not sell to patients.
- CAS No.: 3066444-12-7
- Formula: C24H30F3N5O2
- Molecular Weight:477.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
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PARP-1 <10 nM (IC50) |
Chemical Information
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CAS No. 3066444-12-7
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Molecular Weight 477.52
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Formula C24H30F3N5O2
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SMILES
CCC1=CC=C(NC1=O)[C@@H]2CC[C@@H](C2)N3CCN(CC3)C4=CC=C(N=C4C(F)(F)F)C(NC)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)