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Cat. No.: HY-187469

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PARP1-IN-59

PARP1-IN-59 is a PARP1 inhibitor and can be used in research on PARP1-mediated related diseases, such as cancer.

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CAS No.: 2982276-33-3
화학식: C₂₃H₂₃F₂N₅O₃
분자량:455.46

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

PARP1-IN-59 Chemical Structure

CAS No.: 2982276-33-3

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
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Biological Activity

제품 설명

PARP1-IN-59 is a PARP1 inhibitor and can be used in research on PARP1-mediated related diseases, such as cancer^[1].

IC₅₀ & Target

^[1]

PARP-1

All PARP Isoforms :

In Vitro

PARP1-IN-59 (Example 83) is obtained through a series of reactions starting from (2-ethoxycarbonyl) furan-3-ylboronic acid and methyl 4-bromo-3-fluoro-5-nitrobenzoate^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

Chemical Information

CAS No. 2982276-33-3
분자량 455.46
화학식 C₂₃H₂₃F₂N₅O₃
SMILES

FC1=C(CN2CCN(C3=C(F)N=C(C(NC)=O)C=C3)CC2)C=CC4=C1NC(C5=C4OCC5)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Cai S X, et al. Substituted tricyclic compounds as parp inhibitors and the use thereof. WIPO, 2023, WO2023169226A1.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

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PARP1-IN-59

All PARP Isoforms

Biological Activity

제품 설명

IC50 & Target

In Vitro

Chemical Information

순도&문서

References

Calculators

Help & FAQs

PARP1-IN-59 Related Classifications

HY-187469 Related Classifications

Bioz

Keywords

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