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Cat. No.: HY-187469

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PARP1-IN-59

PARP1-IN-59 is a PARP1 inhibitor and can be used in research on PARP1-mediated related diseases, such as cancer.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 2982276-33-3
Formule: C₂₃H₂₃F₂N₅O₃
Masse moléculaire:455.46

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

PARP1-IN-59 Chemical Structure

CAS No.: 2982276-33-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
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Activité biologique

Description

PARP1-IN-59 is a PARP1 inhibitor and can be used in research on PARP1-mediated related diseases, such as cancer^[1].

IC₅₀ & Target

^[1]

PARP-1

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In Vitro

PARP1-IN-59 (Example 83) is obtained through a series of reactions starting from (2-ethoxycarbonyl) furan-3-ylboronic acid and methyl 4-bromo-3-fluoro-5-nitrobenzoate^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2982276-33-3
Masse moléculaire 455.46
Formule C₂₃H₂₃F₂N₅O₃
SMILES

FC1=C(CN2CCN(C3=C(F)N=C(C(NC)=O)C=C3)CC2)C=CC4=C1NC(C5=C4OCC5)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Cai S X, et al. Substituted tricyclic compounds as parp inhibitors and the use thereof. WIPO, 2023, WO2023169226A1.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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PARP1-IN-59

Voir tous les produits spécifiques à Isoform PARP

Activité biologique

Description

IC50 & Target

In Vitro

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

PARP1-IN-59 Related Classifications

HY-187469 Related Classifications

Bioz

Keywords

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