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Cat. No.: HY-161607

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PARP7-IN-21

PARP7-IN-21 (compound 128) is a potent inhibitor of PARP7, with the IC₅₀ of ＜ 10 nM.

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CAS No.: 3034666-02-6
Formule: C₂₄H₂₆F₃N₇O₂
Masse moléculaire:501.50

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

PARP7-IN-21 Chemical Structure

CAS No.: 3034666-02-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

PARP7-IN-21 (compound 128) is a potent inhibitor of PARP7, with the IC₅₀ of ＜ 10 nM^[1].

IC₅₀ & Target

PARP7

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Chemical Information

CAS No. 3034666-02-6
Masse moléculaire 501.50
Formule C₂₄H₂₆F₃N₇O₂
SMILES

O=C1NN=C2C(CC[C@H]2N3C[C@](C(N4CCN(C5=CC=C(C#N)C=N5)CC4)=O)(C)CC3)=C1C(F)(F)F
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Azkarra Therapeutics, Inc.; Oregon Health, et al. Preparation of pyridazin-3(2H)-one and pyridin-2(1H)-one PARP inhibitor compounds. World Intellectual Property Organization, WO2024073133 A1 2024-04-04

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Chemical Information
Pureté et documentation
Références

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PARP7-IN-21

Voir tous les produits spécifiques à Isoform PARP

Activité biologique

Description

IC50 & Target

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

PARP7-IN-21 Related Classifications

HY-161607 Related Classifications

Bioz

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