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Cat. No.: HY-161607

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PARP7-IN-21

PARP7-IN-21 (compound 128) is a potent inhibitor of PARP7, with the IC₅₀ of ＜ 10 nM.

For research use only. We do not sell to patients.

CAS No.: 3034666-02-6
Formula: C₂₄H₂₆F₃N₇O₂
Molecular Weight:501.50

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

PARP7-IN-21 Chemical Structure

CAS No.: 3034666-02-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

PARP7-IN-21 (compound 128) is a potent inhibitor of PARP7, with the IC₅₀ of ＜ 10 nM^[1].

IC₅₀ & Target

PARP7

All PARP Isoforms :

Chemical Information

CAS No. 3034666-02-6
Molecular Weight 501.50
Formula C₂₄H₂₆F₃N₇O₂
SMILES

O=C1NN=C2C(CC[C@H]2N3C[C@](C(N4CCN(C5=CC=C(C#N)C=N5)CC4)=O)(C)CC3)=C1C(F)(F)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Azkarra Therapeutics, Inc.; Oregon Health, et al. Preparation of pyridazin-3(2H)-one and pyridin-2(1H)-one PARP inhibitor compounds. World Intellectual Property Organization, WO2024073133 A1 2024-04-04

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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PARP7-IN-21

All PARP Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

PARP7-IN-21 Related Classifications

HY-161607 Related Classifications