Partricin
Partricin is an aromatic heptaene macrolide antibiotic complex consisting of partricin A and B, an antifungal agent found in Streptomyces aureofaciens. Partricin exhibits antifungal activity. Partricin has poor selective toxicity in the pathogen/host system. Partricin can be used for the research of fungal infections.
For research use only. We do not sell to patients.
- CAS No.: 11096-49-4
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
In Vitro
Partricin complex (24 h) undergoes partial irreversible photoisomerization when exposed to daylight for 24 h, converting partricins A and B into their all-trans isoforms via 28Z→28E and 30Z→30E bond switches[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 11096-49-4
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SMILES
[Partricin]
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Structure Classification
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Initial Source
Streptomyces aureofaciens
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Partricin Related Classifications
HY-N21835 Related Classifications
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