PLK1/BRD4-IN-6
PLK1/BRD4-IN-6 is a PLK1 inhibitor that inhibits PLK1 kinase activity and acetyl-lysine binding of BRD4-BD1 and BRDT-BD1 (IC50 = 0.0099 µM, 2.579 µM, and 8.468 µM, respectively), and shows higher selectivity for PLK1 than BRD4 in biochemical assays. PLK1/BRD4-IN-6 can be used for research on acute myeloid leukemia.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 2250084-67-2
- Formel: C31H43N7O3
- Molecular Weight:561.72
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
PLK1 40 nM (IC50) |
BRD4 (BD1) 28 nM (IC50) |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 2250084-67-2
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Molecular Weight 561.72
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Formel C31H43N7O3
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SMILES
O=C(NC1CCN(C)CC1)C2=CC=C(NC(N=C3N(C4CCCC4)[C@@H]5C)=NC=C3N(C)C5=O)C(OC6CCCC6)=C2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
PLK1/BRD4-IN-6 Related Classifications
HY-190079 Related Classifications
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