1. PROTAC
  2. Ligand for E3 Ligase
  3. VH032 thiol

VH032 thiol (Synonyms: VHL ligand 6)

Cat. No.: HY-111823
Handling Instructions

VH032 thiol (VHL ligand 6) is a VHL ligand, which binds to pan-BET inhibitor JQ1 via a linker to form PROTAC.

For research use only. We do not sell to patients.

VH032 thiol Chemical Structure

VH032 thiol Chemical Structure

CAS No. : 2098836-54-3

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Solution
10 mM * 1 mL in DMSO USD 495 Ask For Quote & Lead Time
Solid
5 mg USD 450 Ask For Quote & Lead Time
10 mg USD 750 Ask For Quote & Lead Time
50 mg USD 2250 Ask For Quote & Lead Time
100 mg USD 3350 Ask For Quote & Lead Time

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Description

VH032 thiol (VHL ligand 6) is a VHL ligand, which binds to pan-BET inhibitor JQ1 via a linker to form PROTAC[1].

IC50 & Target

VHL

 

Molecular Weight

490.64

Formula

C₂₃H₃₀N₄O₄S₂

CAS No.
SMILES

CC(N=CS1)=C1C2=CC=C(CNC([[email protected]@H]3C[[email protected]@H](O)CN3C([[email protected]](C(C)(C)S)NC(C)=O)=O)=O)C=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
References
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This equation is commonly abbreviated as: C1V1 = C2V2

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Keywords:

VH032 thiolVHL ligand 6VHL ligand6VHL ligand-6Ligand for E3 LigaseE3 ligase-recruiting MoietyInhibitorinhibitorinhibit

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VH032 thiol
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