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  3. PROTAC ER Degrader-4

PROTAC ER Degrader-4 

Cat. No.: HY-135309 Purity: 98.05%
Handling Instructions

PROTAC ER Degrader-4 is a von Hippel-Lindau-based PROATC estrogen receptor (ER) degrader, binding to ER with an IC50 of 0.8 nM. PROTAC ER Degrader-4 induces ER degradation in MCF-7 cells with an IC50 of 0.3 nM.

For research use only. We do not sell to patients.

PROTAC ER Degrader-4 Chemical Structure

PROTAC ER Degrader-4 Chemical Structure

CAS No. : 2361114-15-8

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Description

PROTAC ER Degrader-4 is a von Hippel-Lindau-based PROATC estrogen receptor (ER) degrader, binding to ER with an IC50 of 0.8 nM. PROTAC ER Degrader-4 induces ER degradation in MCF-7 cells with an IC50 of 0.3 nM[1].

IC50 & Target[1]

VHL

 

ER

 

In Vitro

PROTAC ER Degrader-4 shows equal to 100% ER degradation at 0.3 μM in the MCF-7 ER degradation cellular assay[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1005.19

Formula

C53H67F3N6O8S

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

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PROTAC ER Degrader-4
Cat. No.:
HY-135309
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