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Referencia número: HY-183847

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PROTAC STAT6 degrader-10

PROTAC STAT6 degrader-10 is a bifunctional STAT6 degrader with a DC₅₀ value of >1 μM. PROTAC STAT6 degrader-10 recruits STAT6 protein to E3 ubiquitin ligase for ubiquitination and subsequent degradation. PROTAC STAT6 degrader-10 can be used for the research of inflammatory disorders, allergies, asthma, eczema.

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No. CAS: 3077464-23-1
Fòrmula: C₄₈H₆₀N₁₀O₆S
Peso molecular:905.12

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

PROTAC STAT6 degrader-10 Chemical Structure

No. CAS: 3077464-23-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Descripciòn

IC₅₀ & Target

STAT6

Ver todos los productos específicos de isoformas PROTACs :

Ver todos los productos específicos de isoformas STAT :

In Vitro

PROTAC STAT6 degrader-10 (I-3) is a STAT6 PROTAC degrader that recruits STAT6 protein to E3 ubiquitin ligase and degrades it^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 3077464-23-1
Peso molecular 905.12
Fòrmula C₄₈H₆₀N₁₀O₆S
SMILES

O=C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(N=CS3)C)C=C2)=O)[C@H](C(C)(C)C)NC(CCCCCN(C)C(C4=CC5=CC=C(C6=CCCN(C(CCN7C=CN=N7)=O)C6)C=C5N4)=O)=O
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Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Bin Yang, et al. Stat6 degraders and uses thereof. WO2025049820A1. 2026-02-28.

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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PROTAC STAT6 degrader-10

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PROTAC STAT6 degrader-10

Ver todos los productos específicos de isoformas PROTACs

Ver todos los productos específicos de isoformas STAT

Actividad biológica

Descripciòn

IC50 & Target

In Vitro

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs