1. PROTAC Stem Cell/Wnt JAK/STAT Signaling
  2. PROTACs STAT
  3. PROTAC STAT6 degrader-10

PROTAC STAT6 degrader-10 is a STAT6 PROTAC degrader with a DC50 value >1 μM and a DCmax value >0.1 μM. PROTAC STAT6 degrader-10 has the potential for application in inflammation-related diseases.

For research use only. We do not sell to patients.

PROTAC STAT6 degrader-10

PROTAC STAT6 degrader-10 Chemical Structure

CAS No. : 3077464-23-1

Size Stock
50 mg   Get quote  
100 mg   Get quote  
250 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Top Publications Citing Use of Products

View All PROTACs Isoform Specific Products:

View All STAT Isoform Specific Products:

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

PROTAC STAT6 degrader-10 is a STAT6 PROTAC degrader with a DC50 value >1 μM and a DCmax value >0.1 μM. PROTAC STAT6 degrader-10 has the potential for application in inflammation-related diseases[1].

IC50 & Target[1]

STAT6

 

In Vitro

PROTAC STAT6 degrader-10 (I-3) is a STAT6 PROTAC degrader that recruits STAT6 protein to E3 ubiquitin ligase and degrades it[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

905.12

Formula

C48H60N10O6S

CAS No.
SMILES

O=C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(N=CS3)C)C=C2)=O)[C@H](C(C)(C)C)NC(CCCCCN(C)C(C4=CC5=CC=C(C6=CCCN(C(CCN7C=CN=N7)=O)C6)C=C5N4)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
PROTAC STAT6 degrader-10
Cat. No.:
HY-183847
Quantity:
MCE Japan Authorized Agent: