PROTAC STAT6 degrader-4
PROTAC STAT6 degrader-4 (Compound 3u247) is a STAT6 PROTAC degrader with a DC50 of 0.04 nM. PROTAC STAT6 degrader-4 promotes the ubiquitination and degradation of STAT6, and is applicable to the research of immune diseases.
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- CAS No.: 3103198-34-8
- Formule: C54H57FN10O5
- Masse moléculaire:945.09
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Activité biologique
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STAT6 0.04 nM (DC50) |
PROTAC STAT6 degrader-4 potently induces STAT6 degradation in cellular systems, with a DC50 of 0.04 nM[1].
PROTAC STAT6 degrader-4 (2 h) inhibits Eotaxin-3 release in IL-4-stimulated blood with an EC50 of 0.3 nM[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3103198-34-8
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Masse moléculaire 945.09
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Formule C54H57FN10O5
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SMILES
CNC1=CC(N(C=C1)C2=CC=NC3=C2C=C(N3C)CN4CC=C(CC4)C5=C(C=C(C=C5F)C(N(C6=CC=C(C=C6)C7CCN(CC7)CC8=CC9=C(N(C(N9C)=O)C%10CCC(NC%10=O)=O)C=C8)C)=O)C)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PROTAC STAT6 degrader-4 Related Classifications
HY-181901 Related Classifications
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