PROTAC STAT6 degrader-5
PROTAC STAT6 degrader-5 is a PROTAC degrader that selectively targets STAT6. PROTAC STAT6 degrader-5 induces the degradation of STAT6 protein. PROTAC STAT6 degrader-5 can be used in inflammation and cancer research.
For research use only. We do not sell to patients.
- CAS No.: 3077471-62-3
- Formula: C44H45F4N9O5
- Molecular Weight:855.88
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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STAT6 |
PROTAC STAT6 degrader-5 (I-743) is a test compound with potent STAT6 inhibitory activity, categorized as grade A in STAT6 HTRF assay which represents IC50 <0.1 μM in the HTRF binding experiment using biotinylated truncated STAT6 (123-632)-avi system[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3077471-62-3
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Molecular Weight 855.88
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Formula C44H45F4N9O5
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SMILES
FC1=C2C(C=C(N2)C(N(C)C)=O)=C(C3=C(C(F)=C(N4CCN(C5=CC(OC)=C(C=C5F)N[C@H]6C(NC(CC6)=O)=O)CC4)C=C3)F)C=C1C7=CCCN(C(CCN8C=CC=N8)=O)C7
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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