2. PROTAC Stem Cell/Wnt JAK/STAT Signaling
  3. PROTACs STAT
  4. PROTAC STAT6 degrader-5

PROTAC STAT6 degrader-5 is a PROTAC degrader that selectively targets STAT6. PROTAC STAT6 degrader-5 induces the degradation of STAT6 protein. PROTAC STAT6 degrader-5 can be used in inflammation and cancer research.

For research use only. We do not sell to patients.

PROTAC STAT6 degrader-5

PROTAC STAT6 degrader-5 Chemical Structure

CAS No. : 3077471-62-3

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PROTAC STAT6 degrader-5 Related Antibodies

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STAT3 STAT5 STAT6 STAT1

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Description

PROTAC STAT6 degrader-5 is a PROTAC degrader that selectively targets STAT6. PROTAC STAT6 degrader-5 induces the degradation of STAT6 protein. PROTAC STAT6 degrader-5 can be used in inflammation and cancer research[1].

IC50 & Target[1]

STAT6

 

In Vitro

PROTAC STAT6 degrader-5 (I-743) is a test compound with potent STAT6 inhibitory activity, categorized as grade A in STAT6 HTRF assay which represents IC50 <0.1 μM in the HTRF binding experiment using biotinylated truncated STAT6 (123-632)-avi system[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

PROTAC STAT6 degrader-5 Related Antibodies
Molecular Weight

855.88

Formula

C44H45F4N9O5
CAS No.
SMILES

FC1=C2C(C=C(N2)C(N(C)C)=O)=C(C3=C(C(F)=C(N4CCN(C5=CC(OC)=C(C=C5F)N[C@H]6C(NC(CC6)=O)=O)CC4)C=C3)F)C=C1C7=CCCN(C(CCN8C=CC=N8)=O)C7
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PROTAC STAT6 degrader-5 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PROTAC STAT6 degrader-53077471-62-3PROTACsSTATDMSO-d6LC-MS (ESI+)1H NMR spectrumHiBiT-tagged STAT6 proteinSTAT6Inhibitorinhibitorinhibit

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PROTAC STAT6 degrader-5
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