PROTAC STAT6 degrader-5
PROTAC STAT6 degrader-5 is a PROTAC degrader that selectively targets STAT6. PROTAC STAT6 degrader-5 induces the degradation of STAT6 protein. PROTAC STAT6 degrader-5 can be used in inflammation and cancer research.
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- CAS No.: 3077471-62-3
- Formule: C44H45F4N9O5
- Masse moléculaire:855.88
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Description
IC50 & Target
[1]|
STAT6 |
In Vitro
PROTAC STAT6 degrader-5 (I-743) is a test compound with potent STAT6 inhibitory activity, categorized as grade A in STAT6 HTRF assay which represents IC50 <0.1 μM in the HTRF binding experiment using biotinylated truncated STAT6 (123-632)-avi system[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3077471-62-3
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Masse moléculaire 855.88
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Formule C44H45F4N9O5
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SMILES
FC1=C2C(C=C(N2)C(N(C)C)=O)=C(C3=C(C(F)=C(N4CCN(C5=CC(OC)=C(C=C5F)N[C@H]6C(NC(CC6)=O)=O)CC4)C=C3)F)C=C1C7=CCCN(C(CCN8C=CC=N8)=O)C7
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)