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Adenosine

(Synonyms: Adenine riboside; D-Adenosine)
18 Cited Publications
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Based on 18 publication(s) in Google Scholar

Adenosine (Adenine riboside), a ubiquitous and BBB-permeable endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation.

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  • Purity: 99.96%
  • CAS No.: 58-61-7
  • Formula: C10H13N5O4
  • Molecular Weight:267.25
  • Storage:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 1 year , -20°C, 6 months
  • Adenosine Chemical Structure
  • Experimental Validation Results for Adenosine
  • Experimental Validation Results for Adenosine
  • Experimental Validation Results for Adenosine
  • Experimental Validation Results for Adenosine
  • Experimental Validation Results for Adenosine
  • Adenosine Chemical Structure
    Adenosine Chemical Structure
  • Experimental Validation Results for Adenosine
  • Experimental Validation Results for Adenosine
  • Experimental Validation Results for Adenosine
  • Experimental Validation Results for Adenosine
  • Experimental Validation Results for Adenosine
CAS No.: 58-61-7
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In Vivo Efficacy StudyPK/PD AnalysisWBCell Proliferation/Viability Assay
  • In Vivo Efficacy Study
  • In Vivo Efficacy Study
  • PK/PD Analysis
  • Cell Proliferation/Viability Assay
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All Endogenous Metabolite Isoforms

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  • Adenosine Chemical Structure
    Adenosine Chemical Structure
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    Adenosine purchased from MedChemExpress. Usage Cited in: Nature. 2026 Jan;649(8096):423-431. [Abstract]

    Customer Validation
     a-c, Direct infusion of Adenosine into the mPFC produced sustained antidepressant-like effects. a, Experimental timeline and representative image of the bilateral infusion site in the mPFC of CRS. Scale bar, 500 µm. b,c, Immobility time in the forced swim test (FST; b) and sucrose preference (c) were measured 24 h after infusion of Adenosine (0.1 µg per side).

  • 1/16

    Adenosine purchased from MedChemExpress. Usage Cited in: Diabetol Metab Syndr. 2025 May 24;17(1):164. [Abstract]

    Customer Validation
     Weight changes in mice. Images of NFD mice, HFD mice, HS mice and HA mice (A); Trends in body weight of mice in NFD, HFD, HS and HA groups, quantitative analysis, n = 12 (B). Abbreviations: NFD, normal-fat diet; HFD, high-fat die; HS, HFD + semaglutide intervention; HA, HFD + Adenosine (20 mg/kg; i.p.; Once daily) intervention.

  • 1/16

    Adenosine purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2024 Jun 14:e2306514. [Abstract]

    Customer Validation
     Adenosine (0.5-6 mg/kg; i.p.; single dose). ICPs and AUCs of adenosine receptor knock‐out (A1−/−, A2a−/−, A2b−/−, A3−/−) and WT mice. N = 8 in each group. Statistical analysis was performed using an unpaired t‐test. * P < 0.05, **** P < 0.0001.

  • 1/16

    Adenosine purchased from MedChemExpress. Usage Cited in: Theranostics. 2024 Aug 12;14(12):4874-4893. [Abstract]

    Customer Validation
     The percentages of CD25+, CD69+ and CD154+ activated CD4+ T cells among the untreated group (NA), control group (Ctrl) and ADO (Adenosine, 5 mM; 24 h) group.

  • 1/16

    Adenosine purchased from MedChemExpress. Usage Cited in: Int J Mol Med. 2016 Sep;38(3):969-75. [Abstract]

    Customer Validation
     Effects of Adenosine and CGS21680 on CD39 and CD73 expression. (A) Adenosine and CGS21680 promote the expression of CD39. (B) Adenosine and CGS21680 promote the expression of CD73. GAPDH is used as an internal reference.

  • Adenosine