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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
913 Results for "
1,2-dioxetane ring
" in MedChemExpress (MCE) Product Catalog:
Products (913)
913 Results for "1,2-dioxetane ring" in MCE Product Catalog:
3
3 Cited Publications
Cat. No.: HY-P71791
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TRIM21; ring Finger Protein 81; Tripartite Motif Containing 21; 52 KDa Ro Protein; SSA1; Ro/SSA 52kDa; RNF81; Ro(SS-A); SS-A; RO52; E3 Ubiquitin-Protein Ligase TRIM21; ring-Type E3 Ubiquitin Transferase TRIM21; Sjogren Syndrome Antigen A1 (52kDa, Ribonucleoprotein Autoantigen SS-A/Ro); Tripartite Motif-Containing 21; 52 KDa Ribonucleoprotein Autoantigen Ro/SS-A; Tripartite Motif-Containing Protein 21; Sjoegren Syndrome Type A Antigen; Sicca Syndrome Antigen A; Ro/SSA; SSA
Species:
Human
Source:
P. pastoris
2
2 Cited Publications
Target:
Research Areas:
Nitrocefin is a highly activated, chromogenic cephalosporin derivative. Nitrocefin is a chromogenic β-lactamase substrate. Nitrocefin undergoes a distinctive color change from yellow to red as the amide bond in the β-lactam ring is hydrolyzed by β-lactamase. Nitrocefin is used in competitive inhibition studies in developmental work on β-lactamase-resistant antibiotics .
2
Research Areas:
Bis(4-nitrophenyl) phosphate (BNPP) is an esterase inhibitor, inhibits the activity of esterases such as carboxylesterase. Bis(4-nitrophenyl) phosphate inhibits the degradation of Abiraterone in fresh plasma. Bis(4-nitrophenyl) phosphate can be used as a substrate to determine the enzymatic activity of phosphodiesterase in the roots of wetland plants. Bis(4-nitrophenyl) phosphate also acts as a catalyst for metallomicelles and a catalyst that promotes ring-opening polymerization (ROP) .
2
2
Target:
Research Areas:
UCM05 (G28UCM) is a fatty acid synthase (FASN) and filamentous temperature-sensitive protein Z (Ftsz) inhibitor. UCM05 inhibits fatty acid synthesis, viral replication, and Gram-positive bacterial growth. UCM05 binds to FtsZ GTP-binding sites, inhibits GTPase activity, and disrupts Z-ring localization. UCM05 can be used for the research of HSV-1/2 infection, HIV-1 infection, and Gram-positive bacterial infections[1][2][3].
2
2 Cited Publications
Target:
Research Areas:
N3-TEMPO is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
2
2 Cited Publications
Cat. No.: HY-P71340
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: STUB1; CLL-Associated Antigen KW-8; STIP1 Homology And U-Box Containing Protein 1; Antigen NY-CO-7; CHIP; STIP1 Homology And U-Box Containing Protein 1, E3 Ubiquitin Protein Ligase; SDCCAG7; Heat Shock Protein A Binding Protein 2 (C-Terminal); HSPABP2; STIP1 Homology And U Box-Containing Protein 1; NY-CO-7; Serologically Defined Colon Cancer Antigen 7; UBOX1; ring-Type E3 Ubiquitin Transferase; Carboxy Terminus Of Hsp70-Interacting Protein; SCAR16; ring-Type E3 Ubiquitin Transferase CHIP; SCA48; E3 Ubiquitin-Protein Ligase CHIP
Species:
Human
Source:
E. coli
1
1
1 Cited Publications
Cat. No.: HY-W076313
CAS No.: 959150-64-2
Target:
Research Areas:
2-(2,6-Dioxopiperidin-3-yl)-4-iodoisoindoline-1,3-dione is a derivative of Thalidomide with an iodine atom on the benzyl ring
1
Category:
Infection Microorganisms Macrolide Antibiotics Antibiotics Anti-parasitic Disease Research Antibacterial Disease Research Fields
Target:
1
1 Cited Publications
Cat. No.: HY-D1416
CAS No.: 1287651-36-8
1
1
1 Cited Publications
Target:
Research Areas:
ACP-5862 is a major active, circulating, pyrrolidine ring-opened metabolite of Acalabrutinib with an IC50 of 5.0 nM for Bruton tyrosine kinase (BTK). ACP‐5862 is a weak time‐dependent inactivator of CYP3A4 and CYP2C8. Acalabrutinib is an orally active, irreversible, and highly selective BTK inhibitor, with an IC50 of 3 nM and EC50 of 8 nM .
1
1 Cited Publications
Cat. No.: HY-108368A
CAS No.: 2098500-94-6
Target:
Research Areas:
Azido-PEG2-CH2COOH (CHA) is a azido-modified PEG2 acid, can be used as a click chemistry reagent . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
1
1
Target:
Research Areas:
Phosphodiesterase I (PDE) is an enzyme that can catalyze the hydrolysis of the 3' ring phosphate bond of cyclic nucleotides, and is often used in biochemical research. Phosphodiesterase I acts as an important regulator of signal transduction mediated by the second messenger molecules cAMP and cGMP. According to their specificity to cyclic nucleotides, they can also be divided into different types, such as PDE1-PDE11, which also have certain potential in various diseases .
1
1 Cited Publications
Target:
1
1 Cited Publications
Research Areas:
Sulfo-SANPAH is a primary amine-nitrobenzene azide cross-linker. Sulfo-SANPAH improves the functionalization process of PDMS surfaces, is covalently bound to the PAAm gel surface. Sulfo-SANPAH is widely used to crosslink ECM proteins to various substrates, including acrylic-based hydrogels, such as polyacrylamide hydrogels. Sulfo-SANPAH facilitates covalent binding through its negatively charged sulfonate group on its N-hydroxysuccinimide ester ring and a photoactivated phenyl azide group that is highly reactive with nucleophiles and free radicals .
1
1 Cited Publications
Cat. No.: HY-174138
Target:
Research Areas:
NF-κB p105 degrader-1 is a non-covalent, selective Molecular glue-like degrader targeting the NF-κB p105 subunit. NF-κB p105 degrader-1 induces proteasome-mediated degradation via the Cullin-RING ligase SCFβTrCP. NF-κB p105 degrader-1 inhibits LPS-induced production of NO and TNF-α. NF-κB p105 degrader-1 can be used in inflammation-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
