1086 Results for "

adenosine

" in MedChemExpress (MCE) Product Catalog:
Products (1086)

1086 Results for "adenosine" in MCE Product Catalog:

30
30 Cited Publications
Cat. No.: HY-B1511A
CAS No.: 37839-81-9
Synonyms: Cyclic adenosine monophosphate sodium; adenosine cyclic 3', 5'-monophosphate sodium; cAMP sodium
Cyclic AMP (Cyclic adenosine monophosphate) sodium, adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP sodium is an important second messenger in many biological processes .
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22
22 Cited Publications
Cat. No.: HY-A0181
CAS No.: 61-19-8
Synonyms: AMP
Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .
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22
22 Cited Publications
Cat. No.: HY-W011012
CAS No.: 4578-31-8
Adenosine 5'-monophosphate disodium is an orally active purine nucleotide, and participates in ATP metabolism. Adenosine 5'-monophosphate disodium is also a ligand for adenosine 2B receptor. Adenosine 5'-monophosphate disodium can activate AMPK in skeletal muscle, and ameliorates insulin resistance and impaired glucose metabolism. Adenosine 5'-monophosphate disodium can be used for research of diabetes .
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22
22 Cited Publications
Cat. No.: HY-A0181A
CAS No.: 18422-05-4
Synonyms: 5'-AMP monohydrate
Adenosine 5'-monophosphate monohydrate is an adenosine A1 receptor agonist. Adenosine 5'-monophosphate monohydrate has significant antiviral activity against HSV-1 and HSV-2 .
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20
20 Cited Publications
Cat. No.: HY-W010968
CAS No.: 149022-20-8
Synonyms: A-5'-P sodium hydrate; AMP sodium hydrate; adenosine 5'-monophosphate sodium hydrate
5'-Adenylic acid (sodium hydrate) (A-5'-P (sodium hydrate); AMP (sodium hydrate); Adenosine 5'-monophosphate (sodium hydrate)) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
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20
20 Cited Publications
Cat. No.: HY-19528
CAS No.: 979-92-0
Synonyms: SAH (S-Adenosylhomocysteine)
SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine . SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 µM .
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18
18 Cited Publications
Cat. No.: HY-19533
CAS No.: 160098-96-4
Target:  

Adenosine Receptor

Research Areas:  

Cancer

SCH 58261 is a potent, selective and competitive antagonist of adenosine A2A receptor with an IC50 of 15 nM, and displays 323-, 53- and 100-fold more selective for A2A receptor than A1, A2B, and A3 receptors, respectively .
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18
18 Cited Publications
Cat. No.: HY-N0262
CAS No.: 73-03-0
Synonyms: 3'-Deoxyadenosine
Cordycepin (3'-Deoxyadenosine) is a nucleoside derivative and inhibits IL-1β-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts (RASFs) in a dose-dependent manner . Cordycepin kills Mycobacterium tuberculosis through hijacking the bacterial adenosine kinase .
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16
16 Cited Publications
Cat. No.: HY-12957
CAS No.: 1044589-82-3
Purity:  98.00%
Synonyms: 7-Deaza-2'-C-acetylene-adenosine
Research Areas:  

Infection

NITD008 is a potent and selective flaviviruse inhibitor which can inhibit Dengue Virus Type 2 (DENV-2) with an EC50 of 0.64 μM. NITD008 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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16
16 Cited Publications
Cat. No.: HY-N0092
CAS No.: 58-63-9
Inosine is an endogenous purine nucleoside produced by catabolism of adenosine. Inosine has anti-inflammatory, antinociceptive, immunomodulatory and neuroprotective effects. Inosine is an agonist for adenosine A1 (A1R) and A2A (A2AR) receptors .
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16
16 Cited Publications
Cat. No.: HY-10888
CAS No.: 155270-99-8
Purity:  99.89%
Synonyms: KW-6002
Target:  

Adenosine Receptor

Research Areas:  

Neurological Disease

Istradefylline is a very potent, selective and orally active adenosine A2A receptor antagonist with Ki of 2.2 nM in experimental models of Parkinson's disease.
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16
16 Cited Publications
Cat. No.: HY-19532
CAS No.: 139180-30-6
Target:  

Adenosine Receptor

Research Areas:  

Neurological Disease Cancer

ZM241385 is a potent, high affinity and selective adenosine A2a receptor (A2AR) antagonist with a Ki value of 1.4 nM .
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15
15 Cited Publications
Cat. No.: HY-103248
CAS No.: 606-58-6
Purity:  99.78%
Synonyms: Vengicide
Toyocamycin (Vengicide) is an adenosine analog produced by Streptomyces diastatochromogenes, acts as an XBP1 inhibitor. Toyocamycin blocks RNA synthesis and ribosome function, and induces apoptosis. Toyocamycin affects IRE1α-XBP1 pathway, and inhibits XBP1 mRNA cleavage with an IC50 value of 80 nM with affecting IRE1α auto-phosphorylation. Toyocamycin specifically inhibits CDK9 with an IC50 value of 79 nM .
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14
14 Cited Publications
Cat. No.: HY-13201
CAS No.: 120225-54-9
Target:  

Adenosine Receptor

Research Areas:  

Neurological Disease

CGS 21680 is a selective adenosine A2A receptor agonist, with a Ki of 27 nM.
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14
14 Cited Publications
Cat. No.: HY-13201A
CAS No.: 124431-80-7
Purity:  99.70%
Target:  

Adenosine Receptor

Research Areas:  

Neurological Disease

CGS 21680 Hydrochloride is a selective adenosine A2A receptor agonist with a Ki of 27 nM.
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14
14 Cited Publications
Cat. No.: HY-B0140
CAS No.: 317-34-0
Aminophylline is a competitive phosphodiesterase 3/4 (PDE3/4) inhibitor. Aminophylline also acts as an adenosine receptor antagonist. Aminophylline elevates intracellular cAMP levels via competitive inhibition of PDE3 and PDE4, antagonizes adenosine A1 receptor (ADORA1), regulates intracellular calcium signaling and synaptic vesicle cycling, upregulates the PPAR signaling pathway, and downregulates glutamatergic synaptic pathways simultaneously. Aminophylline can be used in research related to major depressive disorder, epilepsy, asthma, and chronic obstructive pulmonary disease (COPD) .
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14
14 Cited Publications
Cat. No.: HY-B0809
CAS No.: 58-55-9
Synonyms: 1,3-Dimethylxanthine; Theo-24
Theophylline (1,3-Dimethylxanthine) is a potent phosphodiesterase (PDE) inhibitor, adenosine receptor antagonist, and histone deacetylase (HDAC) activator. Theophylline (1,3-Dimethylxanthine) inhibits PDE3 activity to relax airway smooth muscle. Theophylline (1,3-Dimethylxanthine) has anti-inflammatory activity by increase IL-10 and inhibit NF-κB into the nucleus. Theophylline (1,3-Dimethylxanthine) induces apoptosis. Theophylline (1,3-Dimethylxanthine) can be used for asthma and chronic obstructive pulmonary disease (COPD) research .
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13
13 Cited Publications
Cat. No.: HY-15424
CAS No.: 24386-93-4
Purity:  99.64%
Synonyms: NSC 113939; 5-ITu
Target:  

Adenosine Kinase

Research Areas:  

Cancer

5-Iodotubercidin (NSC 113939), an ATP mimetic, is a potent adenosine kinase inhibitor with an IC50 of 26 nM. 5-Iodotubercidin (NSC 113939) initiates glycogen synthesis in isolated hepatocytes by causing inactivation of phosphorylase and activation of glycogen synthase. 5-Iodotubercidin (NSC 113939) also inhibits CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2, PKC and Haspin .
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12
12 Cited Publications
Cat. No.: HY-18649
CAS No.: 222631-44-9
Synonyms: BCX4430 hydrochloride; Immucillin-A hydrochloride
Research Areas:  

Infection

Galidesivir (BCX4430) hydrochloride, an adenosine analog and a direct-acting antiviral agent, disrupts viral RNA-dependent RNA polymerase (RdRp) activity. Galidesivir hydrochloride is active in vitro against many RNA viral pathogens, including the filoviruses and emerging infectious agents such as MERS-CoV, SARS-CoV, and SARS-CoV-2. Galidesivir hydrochloride inhibits some negative-sense RNA viruses with EC50s ranging from ~3 to ~68 μM .
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12
12 Cited Publications
Cat. No.: HY-18649A
CAS No.: 249503-25-1
Synonyms: BCX4430; Immucillin-A
Research Areas:  

Infection

Galidesivir (BCX4430), an adenosine analog and a direct-acting antiviral agent, disrupts viral RNA-dependent RNA polymerase (RdRp) activity. Galidesivir is active in vitro against many RNA viral pathogens, including the filoviruses and emerging infectious agents such as MERS-CoV, SARS-CoV, and SARS-CoV-2. Galidesivir inhibits some negative-sense RNA viruses with EC50s ranging from ~3 to ~68 μM .
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