1431 Results for "

fluorometric imaging plate reader

" in MedChemExpress (MCE) Product Catalog:
Products (1431)

1431 Results for "fluorometric imaging plate reader" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-106244A
CAS No.: 177943-89-4
Purity:  99.82%
Synonyms: Oxodotreotide acetate
Research Areas:  

Cancer

DOTATATE acetate is a DOTA-conjugated peptide. DOTATATE acetate can be labelled with radionuclides for positron emission tomography (PET) imaging and peptide receptor radionuclide research (PRRT) . DOTATATE (acetate) can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
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4
4 Cited Publications
Cat. No.: HY-A0168
CAS No.: 313348-27-5
Synonyms: CVT-3146
Target:  

Adenosine Receptor

Research Areas:  

Cardiovascular Disease Cancer

Regadenoson (CVT-3146) is a selective A2A adenosine receptor agonist and vasodilator that increases coronary blood flow, can be used in study of myocardial perfusion imaging. Regadenoson also increases the permeability of the blood-brain barrier (BBB) in rodents, can be used to study increased delivery of agents to the human CNS .
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4
4 Cited Publications
Cat. No.: HY-P2336A
Target:  

Melanocortin Receptor

Research Areas:  

Cancer

CCZ01048 TFA, a α-MSH analogue, exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a Ki of 0.31 nM. CCZ01048 TFA shows rapid internalization into B16F10 melanoma cells and high in vivo stability. CCZ01048 TFA is a promising candidate for PET imaging of malignant melanoma .
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4
4 Cited Publications
Cat. No.: HY-D1373
CAS No.: 156840-13-0
Synonyms: HBC 530
HBC (HBC 530) is a GFP fluorophore-like synthetic dye, with a structurally rigid electron acceptor and a strong electron donor. HBC has a low fluorescence background, and when combined with Pepper (RNA aptamer), HBC forms a tight complex and activates and emits bright fluorescence (Kd of ~3.5 nM). HBC emission peaks vary in different complexes and covers the spectrum from cyan to red. HBC can be used in the live cell imaging of RNA (Em/Ex = 530/485 nm) .
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4
4 Cited Publications
Cat. No.: HY-139109
CAS No.: 115970-66-6
Purity:  99.87%
Synonyms: ADS 780WS
IR-783 (ADS 780WS) is a heptamethine cyanine dye. IR-783 induces Mitochondrial membrane potential loss, ATP depletion, mitochondrial permeability transition pore opening, Cytochrome c release and Apoptosis in breast cancer cells. IR-783 promotes the translocation of Drp1 from the cytosol to mitochondria. IR-783 increases the expression of mitochondrial fission proteins such as MFF and Fission-1. IR-783 possesses imaging, cancer-targeting and anticancer properties. IR-783 exerts anticancer effects against breast cancer. IR-783 can be used in breast cancer-related research .
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3
3 Cited Publications
Cat. No.: HY-100832
CAS No.: 1872382-47-2
Purity:  99.50%
Research Areas:  

Cancer

UNC3866 is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen (IC50=66±1.2 nM) and is more than 100-fold selective for CBX7 over the other nine members of this methyl-lysine (Kme) reader panel.
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3
3 Cited Publications
Cat. No.: HY-125837A
CAS No.: 2748239-18-9
Purity:  ≥98.0%
Research Areas:  

Cancer

MS31 trihydrochloride is a potent, highly affinity and selective fragment-like methyllysine reader protein spindlin 1 (SPIN1) inhibitor. MS31 trihydrochloride potently inhibits the interactions between SPIN1 and H3K4me3 (IC50=77 nM, AlphaLISA; 243 nM, FP). MS31 trihydrochloride selectively binds Tudor domain II of SPIN1 (Kd=91 nM). MS31 trihydrochloride potently inhibits binding of trimethyllysine-containing peptides to SPIN1, and is not toxic to nontumorigenic cells .
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3
3 Cited Publications
Cat. No.: HY-111653
CAS No.: 1247879-16-8
Purity:  99.72%
CycLuc1 is a blood-brain barrier permeable luciferase substrate that displays near-infrared (NIR) emission with a peak luminescence wavelength of 599 nm. CycLuc1 can be used for in vivo bioluminescence imaging .
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3
3 Cited Publications
Cat. No.: HY-P76012
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: RSPO1; R-Spondin Homolog (Xenopus Laevis); R-Spondin 1; R-Spondin Homolog; Roof plate-Specific Spondin-1; CRISTIN3; R-Spondin-1; HRspo1; FLJ40906; RSPO; RSPONDIN
Species:  
Mouse
Source:  
CHO
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3
3 Cited Publications
Cat. No.: HY-148761
CAS No.: 2192281-54-0
Purity:  99.67%
Synonyms: PSMA I&T; PNT-2002
Target:  

PSMA

Research Areas:  

Cancer

Zadavotide guraxetan (PSMA I&T; PNT-2002) is an effective inhibitor of prostate-specific membrane antigen (PSMA). Zadavotide guraxetan can be used for SPECT/CT imaging and radionuclide studies in triple-negative breast cancer and prostate cancer (PCa) .
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3
3 Cited Publications
Cat. No.: HY-135368
CAS No.: 2351898-91-2
Purity:  ≥98.0%
Target:  

Fluorescent Dye

Research Areas:  

Others

8pyDTZ is a pyridyl diphenylterazine (DTZ) analog and an ATP-independent pyridyl substrate of LumiLuc luciferase. 8pyDTZ exhibits spectrally shifted emission. 8pyDTZ has excellent biocompatibility and superior in vivo sensitivity. 8pyDTZ can be used for in vivo luminescence imaging .
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3
3 Cited Publications
Cat. No.: HY-D1389
CAS No.: 2419286-92-1
Synonyms: Sulfo-Cyanine5.5 NHS ester tripotassium
Sulfo-CY-5.5 NHS ester (Sulfo-Cyanine5.5 NHS ester) tripotassium is an amine-reactive ester of sulfonated far-red Cyanine5.5 fluorophore, which can be used to label antibodies, proteins, etc., as well as for in vivo NIR imaging .
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3
3 Cited Publications
Cat. No.: HY-137331
CAS No.: 2374782-04-2
Purity:  98.57%
Synonyms: FAPI-46
Target:  

FAP

Research Areas:  

Cancer

FAPI-46 is a quinoline-based fibroblast activation protein (FAP)-targeted tracer. Use radioactivity FAPI-46 labeled with 68Ga or 177Lu can be used for tumor imaging in a variety of cancers and has higher tumor uptake rates and longer tumor accumulation .
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3
3 Cited Publications
Cat. No.: HY-D2346
HBmito Crimson is a deep red fluorescent probe (λex: 658 nm, λem: 678 nm) for the inner mitochondrial membrane. HBmito Crimson is a cell membrane-permeable probe with high selectivity for the mitochondrial inner membrane, suitable for specific fluorescence staining of the inner mitochondrial membrane in living cells. HBmito Crimson has high photostability and brightness, suitable for long-term dynamic fluorescence imaging.
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3
3 Cited Publications
Cat. No.: HY-103169
CAS No.: 316173-57-6
Purity:  99.94%
Target:  

Adenosine Receptor

Research Areas:  

Neurological Disease

SCH442416 is a potent, selective and brain-penetrant antagonist of adenosine A2A receptor (A2AR), with Kis of 0.048 and 0.5 nM for human and rat A2AR respectively. SCH442416 displays more than 23000-fold selectivity over A1R, A2BR, and A3R (Ki=1111, 10000, and 10000 nM, respectively). SCH442416 can be used for imaging of adenosine A2A receptors in rat and primate brain .
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3
3 Cited Publications
Cat. No.: HY-D1583
CAS No.: 2360411-64-7
Synonyms: DBCO-Cy5 hexafluorophosphate; Cyanine5 dibenzocyclooctyne hexafluorophosphate
Cyanine5 DBCO (DBCO-Cy5) hexafluorophosphate is a low-toxicity azide reactive probe (NIR fluorescent dye), for imaging azide-labeled biomolecules via a copper-free "click-through" reaction. Cyanine5 DBCO hexafluorophosphate has no apparent cytotoxicity or animal toxicity and shows no damage to the physiological functions of cells other than the target cells (azide-labeled cells). Cyanine5 DBCO hexafluorophosphate can be used to label and track cells in vitro and in vivo (Ex=635 nm, Em=650-700 nm) .
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2
2 Cited Publications
Cat. No.: HY-120166
CAS No.: 214491-43-7
Purity:  99.05%
Synonyms: 6,8-Difluoro-4-methylumbelliferyl phosphate
Target:  

Phosphatase

Research Areas:  

Others

DiFMUP is a fluorogenic substrate, and has been widely used for the continuous detection of phosphatase activities. DiFMUP is hydrolysis by a phosphatase results in the release of Xuorescent DIFMU, which can be easily followed in continuous mode by a Xuorescence reader .
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2
2 Cited Publications
Cat. No.: HY-172286
CAS No.: 1432019-64-1
Cy7 NHS ester is a fluorescent dye that can be used for fluorescent imaging study.
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2
2 Cited Publications
Cat. No.: HY-D1250
CAS No.: 1859102-62-7
Mito-TRFS, the first off-on probe, is used to image the mitochondrial thioredoxin reductase (TrxR2) in live cells .
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2
2 Cited Publications
Cat. No.: HY-D1252
CAS No.: 2966536-18-3
Fast-TRFS is a selective and superfast fluorogenic probe of thioredoxin reductase (TrxR). Fast-TRFS can be used for imaging TrxR activity in live cells .
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