1389 Results for "

acetyl marks

" in MedChemExpress (MCE) Product Catalog:
Products (1389)

1389 Results for "acetyl marks" in MCE Product Catalog:

7
7 Cited Publications
Cat. No.: HY-113596
CAS No.: 102029-73-2
Purity:  99.22%
Synonyms: acetyl-CoA trisodium
Acetyl-coenzyme A (Acetyl-CoA) trisodium is a membrane-impermeant central metabolic intermediate, participates in the TCA cycle and oxidative phosphorylation metabolism. Acetyl-coenzyme A trisodium, regulates various cellular mechanisms by providing (sole donor) acetyl groups to target amino acid residues for post-translational acetylation reactions of proteins. Acetyl Coenzyme A trisodium is also a key precursor of lipid synthesis .
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7
7 Cited Publications
Cat. No.: HY-113596A
CAS No.: 32140-51-5
Purity:  97%
Synonyms: acetyl-CoA lithium
Acetyl-coenzyme A (Acetyl-CoA) lithium is a membrane-impermeant central metabolic intermediate, participates in the TCA cycle and oxidative phosphorylation metabolism. Acetyl-coenzyme A lithium, regulates various cellular mechanisms by providing (sole donor) acetyl groups to target amino acid residues for post-translational acetylation reactions of proteins. Acetyl Coenzyme A lithium is also a key precursor of lipid synthesis .
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6
6 Cited Publications
Cat. No.: HY-A0083
CAS No.: 62-51-1
Synonyms: acetyl-β-methylcholine chloride
Target:  

mAChR

Research Areas:  

Others

Methacholine (Acetyl-β-methylcholine) choride is a potent muscarinic-3 (M3) agonist. Methacholine choride acts directly on acetylcholine receptors on smooth muscle causing bronchoconstriction and airway narrowing. Methacholine choride shows a high sensitivity to identify bronchial hyperresponsiveness (BHR). Methacholine choride can be used to measure airway hyperresponsiveness (AHR) as a diagnostic aid in the assessment of individuals with asthma-like symptoms and normal resting expiratory flow rates .
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5
5 Cited Publications
Cat. No.: HY-P1003
CAS No.: 169332-61-0
Target:  

Fluorescent Dye

Research Areas:  

Others

Ac-DEVD-AMC is a fluorescent substrate of caspase-3/caspase-7. When treating Ac-DEVD-AMC with cell lysate, Ac-DEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection, with an excitation wavelength of 380 nm and an emission wavelength of 460 nm .
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5
5 Cited Publications
Cat. No.: HY-124960
CAS No.: 586976-24-1
Purity:  ≥98.0%
Research Areas:  

Cancer

CTPB is a good activator of p300 histone acetyl transferase (HAT) enzyme .
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5
5 Cited Publications
Cat. No.: HY-N4072
CAS No.: 134859-96-4
6''-O-Acetylglycitin, a acetyl glucoside, is one of the isoflavone isomer in soybeans, shows various extents of content reduction dependent on storage temperature, packaging condition, and its isoflavone isomer kind .
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5
5 Cited Publications
Cat. No.: HY-19541
CAS No.: 1640282-31-0
I-CBP112, a chemical probe, is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor, that inhibits the CBP/p300 bromodomains, enhances acetylation by p300.
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5
5 Cited Publications
Cat. No.: HY-107569
CAS No.: 78824-30-3
Purity:  ≥99.0%
Garcinol, a polyisoprenylated benzophenone harvested from Garcinia indica, exerts anti-cholinesterase properties towards acetyl cholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50s of 0.66 μM and 7.39 μM, respectively . Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 μM) and p300/CPB-associated factor (PCAF, IC50 = 5 μM). Garcinol has anti-inflammatory and anti-cancer activity .
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5
5 Cited Publications
Cat. No.: HY-15142R
CAS No.: 25316-40-9
Synonyms: Hydroxydaunorubicin hydrochloride (Standard); ADR (Standard)
Doxorubicin hydrochloride (Standard) is the analytical standard of Doxorubicin hydrochloride. This product is intended for research and analytical applications. Doxorubicin (Hydroxydaunorubicin) hydrochloride, a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy .
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4
4 Cited Publications
Cat. No.: HY-P2161B
Target:  

Kisspeptin Receptor

Research Areas:  

Cancer

TAK-683 acetate is a potent full KISS1 receptor (KISS1R) agonist (IC50=170 pM) with improved metabolic stability. TAK-683 acetate is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC50 values of 0.96 nM and 1.6 nM for human and rat, respectively . TAK-683 acetate depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer .
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4
4 Cited Publications
Cat. No.: HY-N0892
CAS No.: 67416-61-9
Synonyms: acetyl-11-keto-β-boswellic acid
AKBA (Acetyl-11-keto-β-boswellic acid) is an active triterpenoid compound from the extract of Boswellia serrate and a novel Nrf2 activator.
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4
4 Cited Publications
Cat. No.: HY-W096600
CAS No.: 188783-78-0
Synonyms: 1,3,4-Tri-O-acetyl-2-deoxy-2-fluoro-L-fucopyranos
Target:  

Glycosyltransferase

Research Areas:  

Cancer

2F-Peracetyl-Fucose (1,3,4-Tri-O-acetyl-2-deoxy-2-fluoro-L-fucopyranos) acts as a potent fucosyltransferase (FUT) inhibitor .
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4
4 Cited Publications
Cat. No.: HY-107709
CAS No.: 1039758-22-9
Purity:  99.04%
Research Areas:  

Metabolic Disease

MK-4074 is a liver-specific inhibitor of acetyl-CoA carboxylase ACC1 and ACC2 with IC50 values of approximately 3 nM.
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4
4 Cited Publications
Cat. No.: HY-125798
CAS No.: 24967-27-9
Purity:  ≥98.0%
Synonyms: Neu5Ac2en; DANA
Target:  

Influenza Virus

Research Areas:  

Infection

N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid (Neu5Ac2en) is a potent neuraminidase (sialidase) inhibitor. N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid shows inhibitory activities against human neuraminidase enzymes with IC50s of 143, 43, 61, and 74 μM for NEU1, NEU2, NEU3, and NEU4, respectively. Anti-influenza virus activity .
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4
4 Cited Publications
Cat. No.: HY-12942
CAS No.: 1301214-47-0
Purity:  98.46%
Research Areas:  

Metabolic Disease

PF-05175157 is broad spectrum acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 27.0, 33.0, 23.5 and 50.4 nM for ACC1 (human), ACC2 (human), ACC1 (rat), ACC2 (rat), respectively.
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3
3 Cited Publications
Cat. No.: HY-A0132
CAS No.: 7512-17-6
Synonyms: N-acetyl-2-amino-2-deoxy-D-glucose
N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose), the D isomer of N-acetylglucosamine, is an orally active monosaccharide derivative of glucose with anti-tumor and anti-inflammation properties. N-Acetyl-D-Glucosamine is also a bacterial metabolite, which is found in Escherichia coli. N-Acetyl-D-Glucosamine can induce yeast-mycelial conversion in Candida albicans. N-Acetyl-D-Glucosamine also enhances healing of cartilaginous injuries in rabbits .
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3
3 Cited Publications
Cat. No.: HY-136386
CAS No.: 26117-28-2
Purity:  ≥97.0%
Research Areas:  

Inflammation/Immunology

N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group, but cannot enter the glutathione metabolic pathway .
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3
3 Cited Publications
Cat. No.: HY-107854
CAS No.: 1210-83-9
Purity:  99.96%
Synonyms: N-acetylserotonin; Normelatonin; O-Demethylmelatonin
N-Acetyl-5-hydroxytryptamine is a Melatonin precursor, and that it can potently activate TrkB receptor.
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3
3 Cited Publications
Cat. No.: HY-139604
CAS No.: 2623158-64-3
Purity:  99.56%
Target:  

MARK Apoptosis

Research Areas:  

Cancer

PCC0208017 is a microtubule affinity regulating kinases (MARK3/MARK4) inhibitor with IC50s of 1.8 and 2.01 nM, respectively. PCC0208017 has much lower inhibitory activity against MARK1 and MARK2, with IC50s of 31.4 and 33.7 nM, respectively. PCC0208017 suppresses glioma progression in vitro and in vivo. PCC0208017 disrupts microtubule dynamics and induces G2/M phase cell cycle arrest and cell apoptosis. PCC0208017 demonstrates robust antitumor activity in vivo and displays good BBB permeability .
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3
3 Cited Publications
Cat. No.: HY-17042
CAS No.: 83881-51-0
Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response .
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