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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3707 Results for "
Probe
" in MedChemExpress (MCE) Product Catalog:
Products (3707)
3707 Results for "Probe" in MCE Product Catalog:
31
31 Cited Publications
Cat. No.: HY-D0969
CAS No.: 34215-57-1
Synonyms: DiOC18(3); 3,3'-Dioctadecyloxacarbocyanine perchlorate
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28 Cited Publications
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Research Areas:
UNC0642, a chemical probe, is a potent and selective lysine methyltransferases G9a and GLP inhibitor, with an IC50 of <2.5 nM for G9a.
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28 Cited Publications
27
27 Cited Publications
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26 Cited Publications
Cat. No.: HY-D0080
CAS No.: 74515-25-6
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Research Areas:
Laurdan is a membrane-permeable fluorescent probe that displays spectral sensitivity to the phospholipid phase of the cell membrane to which it is bound. Quantitation of generalized polarization (GP) of Laurdan can be used to identify phospholipid phase (Ex/Em = 370/440-490 nm).
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25 Cited Publications
Cat. No.: HY-19725
CAS No.: 1235034-55-5
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A-1155463, a chemical probe, is a highly potent and selective BCL-XL inhibitor with an EC50 of 70 nM in Molt-4 cell. A-1155463 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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25 Cited Publications
Synonyms: bisBenzimide H 33258; H 33258
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24 Cited Publications
Cat. No.: HY-N7131
CAS No.: 38215-36-0
Category:
Alkaloids Other Diseases Plants Umbelliferae Disease Research Fields Ambrosia hispida Indole Alkaloids
Target:
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24 Cited Publications
Cat. No.: HY-19615
CAS No.: 1831110-54-3
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Research Areas:
MS023, a chemical probe, is a potent, selective, and cell-active inhibitor of human type I protein arginine methyltransferases (PRMTs) inhibitor, with IC50s of 30, 119, 83, 4 and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6, and PRMT8, respectively .
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24 Cited Publications
Research Areas:
SGC-CBP30, a chemical probe, is a potent and highly selective CBP/p300 bromodomain (Kds of 21 nM and 32 nM for CBP and p300, respectively) inhibitor, displaying 40-fold selectivity over the first bromodomain of BRD4 [BRD4(1)] bound. SGC-CBP30 strongly reduces secretion of IL-17A in Th17 cells and has anti-inflammatory effects .
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24 Cited Publications
Cat. No.: HY-D0802
CAS No.: 35013-72-0
Synonyms: Biotin N-hydroxysuccinimide ester; NHS-Biotin
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Research Areas:
Dihydrorhodamine 123 (DHR 123) is a non-fluorescent reactive oxygen species (ROS) indicator. Dihydrorhodamine 123 is oxidized to fluorescent Rhodamine 123 (HY-D0816) within cells in the presence of reactive oxygen species and it localizes in mitochondria (Ex/Em = 515/536 nm).
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22 Cited Publications
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Research Areas:
BODIPY-cholesterol is an intrinsically lipophilic, and cell-permeable analog of cholesterol with a fluorescent BODIPY group. BODIPY-cholesterol can be used to monitor sterol uptake and inter-organelle sterol flux in cells. (Excitation/Emission: 505/515 nm) .
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CY7 is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
