Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
629 Results for "
nitric+oxide
" in MedChemExpress (MCE) Product Catalog:
Products (629)
629 Results for "nitric+oxide" in MCE Product Catalog:
5
Target:
Fimasartan (BRA-657) is an orally effective angiotensin receptor AT1 non-peptide antagonist. Fimasartan has antihypertensive effects. Fimasartan improves neuroinflammation and brain injury mediated by NLRP3 inflammatome after intracerebral hemorrhage, and has neuroprotective effect. Fimasartan inhibits the expression of inducible nitric oxide synthase through the inactivation of NF-κB and activator protein-1 .
4
4
4 Cited Publications
Synonyms: Symmetric dimethylarginine; NG,NG'-Dimethyl-L-arginine
Category:
Human Gut Microbiota Metabolites Other disease Ketones, Aldehydes, Acids Disease markers Endogenous metabolite Disease Research Fields Inflammation/Immunology
Target:
4
4 Cited Publications
Cat. No.: HY-N0268
CAS No.: 41743-73-1
Category:
Iridaceae Flavonoids Plants Belamcanda chinensis (Linn.) Redouté Disease Research Fields Inflammation/Immunology Isoflavones
Target:
4
4 Cited Publications
Cat. No.: HY-N0152
CAS No.: 17912-87-7
4
4 Cited Publications
4
Category:
Phenols Polyphenols Amburana cearensis (Allemão) A.C.Sm. Plants Compositae Disease Research Fields Inflammation/Immunology Cancer
Target:
4
4
Target:
4
4 Cited Publications
Synonyms: CNI-1493; CPSI-2364 tetrahydrochloride
Target:
Research Areas:
Semapimod tetrahydrochloride (CNI-1493), an inhibitor of proinflammatory cytokine production, can inhibit TNF-α, IL-1β, and IL-6. Semapimod tetrahydrochloride inhibits TLR4 signaling (IC50≈0.3 μM). Semapimod tetrahydrochloride inhibits p38 MAPK and nitric oxide production in macrophages. Semapimod tetrahydrochloride has potential in a variety of inflammatory and autoimmune disorders .
4
4 Cited Publications
Cat. No.: HY-N0617
CAS No.: 80651-76-9
Category:
Cardiovascular Disease Plants Moraceae Flavanonols Flavonoids Phenols Polyphenols Disease Research Fields Inflammation/Immunology Morus alba Linn.
Target:
4
Target:
Research Areas:
Gabexate mesylate (FOY) is is a competitive and non-antigenic synthetic inhibitor of trypsin-like serine proteinases. Gabexate mesylate inhibits human thrombin, urokinase, plasmin, and Factor Xa with Kis of 0.97, 1.3, 1.6, and 8.5 μM, respectively. Gabexate mesylate binds to human and bovine tryptase with Kis of 3.4 nM and 18 μM, respectively. Gabexate mesylate exerts an anticoagulant effect on the clotting activity of thrombin and has anti-inflammatory effect by viainhibition of NF-κB, proinflammatory cytokines, and nitric oxide. Gabexate mesylate is used for pancreatitis and disseminated intravascular coagulation .
3
3 Cited Publications
Cat. No.: HY-N1382
CAS No.: 14259-45-1
Category:
Iridoids Terpenoids Rubiaceae Plants Disease Research Fields Inflammation/Immunology Hedyotis diffusa Willd.
Target:
3
2
Category:
Alkaloids Ranunculaceae Other Diseases Aconitum carmichaeli Debx. Plants Disease Research Fields Isoquinoline Alkaloids
Target:
2
2 Cited Publications
Target:
Research Areas:
Spermine NONOate is a complex of nitric oxide (NO) with spermine and acts as a NO donor. Spermine NONOate can be used for NO aqueous solutions preparing .
2
2 Cited Publications
Cat. No.: HY-N0577
CAS No.: 26544-34-3
Synonyms: Apigenin 7-O-apiosylglucoside; Apigenin 7-(2-O-apiosylglucoside)
Category:
Flavonoids Flavones Phenols Polyphenols Plants Umbelliferae Disease Research Fields Baccharis sarothroides A.Gray Inflammation/Immunology
Target:
2
Category:
Cardiovascular Disease Stilbenes Polygonaceae Rheum officinale Baill. Phenols Polyphenols Plants Disease Research Fields
Target:
2
Target:
Research Areas:
Ataciguat (HMR-1766) is a nitric oxide-independent soluble guanylate cyclase (sGC) activator. Ataciguat is able to activate the ferric heme-iron redox form of sGC that stimulate the production of cyclic GMP (cGMP). Ataciguat exhibits vasodilator effects .
2
Target:
Research Areas:
Benidipine hydrochloride is an orally active calcium channel antagonist. Benidipine hydrochloride can inhibit cell proliferation and apoptosis. Benidipine hydrochloride has antioxidant activity and can increase nitric oxide synthase activity and improve coronary circulation in hypertensive rats .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
