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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
128 Results for "
prenatal fluoride-induced persistent hyper-osteogenesis
" in MedChemExpress (MCE) Product Catalog:
Products (128)
128 Results for "prenatal fluoride-induced persistent hyper-osteogenesis" in MCE Product Catalog:
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Trichlorfon ethyl is an analog of Trichlorfon (HY-B1220), as well as an inhibitor of Butyrylcholinesterase and Bacillus subtilis Esterase. Trichlorfon ethyl acts as a prenatal brain growth inhibitor, causing mild reductions in total brain weight, medulla oblongata weight and tectum weight in newborn guinea pigs, without affecting cerebellar weight. Trichlorfon ethyl does not induce severe prenatal brain hypoplasia in guinea pig offspring. Trichlorfon ethyl can be used in studies related to brain hypoplasia .
Cat. No.: HY-W585931
CAS No.: 120067-83-6
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Fipronil sulfide is a toxic, persistent metabolite of Fipronil (HY-B0822). Fipronil is a broad-spectrum insecticide .
Cat. No.: HY-W703863
CAS No.: 105779-78-0
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Pyrimidifen is a phenoxyethyl amine compound and is an acaricide. Pyrimidifen controls the African red mite, Eutetranychus africanus with a persistency of 14-21 days .
Cat. No.: HY-147256A
CAS No.: 1276021-10-3
Synonyms: Niferidil
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Cavutilide hydrochloride (Niferidil) is a class III antiarrhythmic agent that inhibits hERG K + channel. Cavutilide hydrochloride has the potential for the study of persistent atrial fibrillation .
Cat. No.: HY-182628
CAS No.: 951248-25-2
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CJ-036878 is a NMDAR NR2B subunit antagonist. CJ-036878 is applicable to research related to persistent inflammatory pain and neuropathic pain .
Cat. No.: HY-W703863S
Cat. No.: HY-U00069
CAS No.: 155273-01-1
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Thionisoxetine is a norepinephrine transporter inhibitor with a Ki value of 0.2 nM in rats, and exhibits anti-hyperalgesic and analgesic activities. Thionisoxetine reverses thermal hyperalgesia and mechanical allodynia in rats. Thionisoxetine can be used in studies related to persistent inflammatory pain .
Cat. No.: HY-182387
CAS No.: 208986-26-9
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NM404 is a targeted radionuclide processing agent with slow clearance. Radioiodine-labeled NM404 is a small-molecule phospholipid ether analog that exhibits significant tumor uptake capacity and persistent tumor retention properties in more than 45 spontaneous and xenograft tumor models .
Cat. No.: HY-116066
CAS No.: 183173-00-4
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YM471 free base is a non-peptide antagonist of vasopressin V1A and V2 receptors with potent and persistent antagonistic activity. YM471 exhibits high affinity for rat V1A and V2 receptors with K values of 0.16 and 0.77 nM, respectively .
Cat. No.: HY-186290
(-)-DMNP is an inhibitor targeting RelZ and Rel_Msm, with activity against mycobacteria. (-)-DMNP binds to structurally similar sites of RelZ and Rel_Msm, thereby inhibiting (p) ppGpp synthesis activity. (-)-DMNP inhibits the formation of persistent mycobacterial cells and eradicates their biofilms. (-)-DMNP can be used in the research of bacterial infections and tuberculosis .
Cat. No.: HY-113798
CAS No.: 112887-62-4
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ICI 198583 is a thymidylate synthase (TS) inhibitor with a Ki value of 10 nM for both mouse and human TS. ICI 198583 serves as a substrate for folylpolyglutamate synthetase (FPGS) with a Km of 40 μM. ICI 198583 exerts persistent, dose-dependent inhibition on thymidylate synthase flux in mice. ICI 198583 is applicable to relevant research on leukemia .
Cat. No.: HY-187733
CAS No.: 77016-85-4
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Plomestane is an orally active second-generation steroidal aromatase inhibitor that, as an enzyme-activated pseudosubstrate, is converted via NADPH-dependent catalysis into a reactive intermediate, which covalently binds to aromatase to produce irreversible inhibition, thereby persistently suppressing peripheral aromatase activity. Plomestane can be used for the study of hormone-dependent breast cancer .
Cat. No.: HY-DY1122
CAS No.: 121461-69-6
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Pyrromethene 556 (solution) is a fluorescent dipyrromethene-BF2 complex laser dye. Pyrromethene 556 (solution) enables immediate and reversible color changes in conventional glass ionomer restorative materials, while it does not cause persistent, visually detectable color changes in other restorative materials .
Solvent and concentration: DMSO: 10 mM
Solvent and concentration: DMSO: 10 mM
Cat. No.: HY-167212
CAS No.: 50733-99-8
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AHR-5645B free base inhibits the binding of 3H-spiperone to membrane sites in the bovine anterior pituitary and blocks the persistent inhibitory effect of dopamine on prolactin secretion. AHR-5645B free base stimulates prolactin secretion in male Sprague-Dawley rats in vivo .
Cat. No.: HY-181987
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PSCdb01560 is a Dengue virus NS5 RNA-dependent RNA polymerase (RdRp) inhibitor. PSCdb01560 binds stably to the conserved allosteric N-pocket of the polymerase, maintains persistent interactions with key residues Arg729 and Arg737, and induces polymerase structure stabilization. PSCdb01560 can be used for the research of dengue virus infection .
Cat. No.: HY-182922
CAS No.: 3054394-56-5
SD-965 is a selective STAT3 PROTAC degrader with a DC50 of 0.14 μM. SD-965 promotes the ubiquitination and degradation of STAT3. SD-965 induces rapid, complete and persistent depletion of STAT3 protein. SD-965 induces tumor regression in mouse xenograft models of leukemia and lymphoma .
Cat. No.: HY-182351
CAS No.: 253306-39-7
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ONO-2921 is an orally active and selective N-type calcium channel blocker. ONO-2921 functionally blocks N-type calcium channels. ONO-2921 reduces paw withdrawal responses during persistent nociception and hyperalgesia to heat in neuropathic pain models. ONO-2921 can be used for research on neuropathic pain and nociceptive pain .
Cat. No.: HY-W714852
CAS No.: 1315501-18-8
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Zeta-Cypermethrin is a type II pyrethroid insecticide. Zeta-Cypermethrin primarily acts on voltage-gated sodium channels in nerve cells, causing delayed channel closure, persistent nerve excitation and convulsions. In Drosophila, Zeta-Cypermethrin rapidly induces extremely high metabolic resistance that can be screened, and exhibits in vitro genotoxicity to human peripheral blood lymphocytes .
Cat. No.: HY-185173
CAS No.: 1309389-73-8
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(E)-3-Benzodioxol-5-yl-N,N-diphenyl-2-propenamide is a chemically synthesized flavoring substance and can be found in toothpaste products. (E)-3-Benzodioxol-5-yl-N,N-diphenyl-2-propenamide is non-genotoxic, shows no genotoxic activity in bacterial reverse mutation and in vitro mammalian cell micronucleus assays. (E)-3-Benzodioxol-5-yl-N,N-diphenyl-2-propenamide does not induce prenatal developmental toxicity in rats .
Cat. No.: HY-182711
CAS No.: 1379615-30-1
SCR0911 is an inhibitor of mycobacterial cytochrome bcc oxidase and Plasmodium falciparum cytochrome bc1. SCR0911 disrupts oxidative phosphorylation by binding to mycobacterial cytochrome bcc, binds to the Qi site of Plasmodium falciparum cytochrome bc1, inhibits mycobacterial cell growth and ATP synthesis, and exhibits broad-spectrum anti-mycobacterial and anti-malarial activities. SCR0911 can be used in research related to tuberculosis, malaria, and isolated persistent hypermethioninemia (iph) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
