Search Result

Results for "

2A6

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (19) AAK1 (2) Acyltransferase (1) ADC Linker (10) Adenosine Receptor (9) Adenylate Cyclase (4) Adrenergic Receptor (15) Akt (10) Aldehyde Dehydrogenase (ALDH) (2) Aldose Reductase (1) Amine N-methyltransferase (2) Amino Acid Derivatives (10) Aminopeptidase (1) AMPK (3) Amylases (1) Amyloid-β (3) Anaplastic lymphoma kinase (ALK) (3) Androgen Receptor (3) Angiotensin Receptor (1) Antibiotic (10) Apolipoprotein (1) Apoptosis (54) Arrestin (2) Atg8/LC3 (3) ATTECs (1) Autophagy (19) AUTOTACs (2) Bacterial (18) Bcl-2 Family (5) BCL6 (1) Bcr-Abl (1) BCRP (2) Beta-secretase (1) Biochemical Assay Reagents (143) Bombesin Receptor (2) Btk (1) c-Kit (2) c-Met/HGFR (1) c-Myc (1) C-type Lectin-like Receptors (CTLRs) (1) Calcium Channel (7) Cannabinoid Receptor (4) Carbonic Anhydrase (3) Casein Kinase (3) Caspase (9) Cathepsin (3) CCR (3) CD44 (2) CDK (24) Checkpoint Kinase (Chk) (2) CHIKV (5) Cholinesterase (ChE) (12) CMV (6) Collagen (1) Complement System (2) Constitutive Androstane Receptor (4) COX (18) CXCR (4) Cyclin G-associated Kinase (GAK) (1) Cyclophilin (1) Cytochrome P450 (113) Deubiquitinase (2) DGK (1) Dipeptidyl Peptidase (2) Discoidin Domain Receptor (1) DNA Methyltransferase (2) DNA Stain (3) DNA/RNA Synthesis (25) Dopamine Receptor (14) Drug Derivative (20) Drug Intermediate (37) Drug Isomer (2) Drug Metabolite (19) E1/E2/E3 Enzyme (1) E3 Ligase Ligand-Linker Conjugates (19) EGFR (15) ELOVL (1) Endogenous Metabolite (44) Enterovirus (3) Environmental Pollutants (8) Ephrin Receptor (1) Epigenetic Reader Domain (2) Epoxide Hydrolase (1) ERK (11) Estrogen Receptor/ERR (1) Eukaryotic Initiation Factor (eIF) (1) Fc Receptor (FcR) (2) Ferrochelatase (2) Ferroptosis (5) FGFR (6) FLAP (1) FLT3 (1) Fluorescent Dye (14) Free Fatty Acid Receptor (1) Fungal (12) G-quadruplex (1) GABA Receptor (4) Glucocorticoid Receptor (9) Glutathione Peroxidase (1) Glycosidase (3) GnRH Receptor (4) GPR35 (2) HBV (2) HCN Channel (2) HCV (5) HCV Protease (3) HDAC (17) Hepcidin (1) Herbicide (2) HIF/HIF Prolyl-Hydroxylase (3) Histamine Receptor (13) Histone Demethylase (3) Histone Methyltransferase (3) HIV (6) HSP (3) HSV (6) IAP (1) IFNAR (2) iGluR (3) IKZF Family (1) Indoleamine 2,3-Dioxygenase (IDO) (2) Influenza Virus (8) Insecticide (2) Insulin Receptor (1) Interleukin Related (21) IPK Superfamily (3) IRAK (3) IRE1 (1) Isotope-Labeled Compounds (189) Itk (1) JAK (4) JNK (2) Keap1-Nrf2 (5) Lactate Dehydrogenase (1) LDLR (1) Leukotriene Receptor (3) Ligands for E3 Ligase (4) Ligands for Target Protein for PROTAC (2) LIM Kinase (LIMK) (1) Lipase (1) Liposome (3) Lipoxygenase (2) LPL Receptor (1) LRRK2 (1) LXR (1) mAChR (4) MAP3K (1) MAP4K (1) MAPKAPK2 (MK2) (2) MCHR1 (GPR24) (1) MDM-2/p53 (3) MEK (3) MELK (1) MetAP (1) Methionine Adenosyltransferase (MAT) (1) Methylenetetrahydrofolate Dehydrogenase (MTHFD) (1) mGluR (2) Microtubule/Tubulin (4) Mineralocorticoid Receptor (4) Mitochondrial Metabolism (3) MMP (5) MNK (1) MOFs (213) Molecular Glues (4) Monoamine Oxidase (4) mTOR (4) nAChR (6) NADH Dehydrogenase (1) NAMPT (1) Necroptosis (5) NEKs (1) Neuropeptide Y Receptor (1) Neurotensin Receptor (1) NF-κB (18) NO Synthase (10) NOD-like Receptor (NLR) (1) Nucleoside Antimetabolite/Analog (109) Olfactory Receptor (1) Opioid Receptor (5) Orexin Receptor (OX Receptor) (1) Orphan Nuclear Receptor (3) Oxidative Phosphorylation (2) P-glycoprotein (3) P2X Receptor (1) P2Y Receptor (41) p38 MAPK (7) p62 (3) PAI-1 (1) PAK (1) Parasite (10) PARP (3) PCSK9 (1) PDGFR (2) PDK-1 (1) PERK (3) Phosphatase (2) Phosphodiesterase (PDE) (2) Phospholipase (3) Phosphoramidites (20) PI3K (9) Pim (1) PKA (1) PKC (2) Potassium Channel (11) PPAR (6) Pregnane X Receptor (PXR) (2) Prion Protein (2) Progesterone Receptor (2) Prostaglandin Receptor (2) PROTAC Linkers (28) PROTACs (12) Protease Activated Receptor (PAR) (1) Proton Pump (1) Pyruvate Kinase (3) Quinone Reductase (2) Radionuclide-Drug Conjugates (RDCs) (1) Raf (1) RANKL/RANK (1) RAR/RXR (2) Ras (2) Reactive Oxygen Species (ROS) (25) Reference Standards (101) RET (2) Reverse Transcriptase (1) Ribosomal S6 Kinase (RSK) (2) RIBOTAC (1) RIP kinase (1) ROCK (7) Salt-inducible Kinase (SIK) (1) SARS-CoV (13) Ser/Thr Kinase (1) Ser/Thr Protease (1) Serotonin Transporter (1) SGLT (1) SHP2 (2) Sirtuin (1) Small Interfering RNA (siRNA) (22) Smo (1) SnRK (1) SOD (7) Sodium Channel (8) Src (4) STAT (5) Survivin (1) TAM Receptor (1) Target Protein Ligand-Linker Conjugates (1) Tau Protein (2) Telomerase (1) TGF-beta/Smad (1) TGF-β Receptor (2) Tie (1) TNF Receptor (11) Toll-like Receptor (TLR) (8) Topoisomerase (3) Trk Receptor (3) TRP Channel (1) TrxR (1) UGT (2) ULK (1) Urotensin Receptor (1) Vasopressin Receptor (3) VD/VDR (3) VEGFR (5) Virus Protease (1) Wee1 (3) Xanthine Oxidase (3) YAP (2) Zinc Finger Protein (1) α-synuclein (1) β-glucuronidase (1)
By Research Areas:	Cancer (358) Cardiovascular Disease (69) Endocrinology (16) Infection (81) Inflammation/Immunology (137) Metabolic Disease (123) Neurological Disease (145)
Click Chemistry:	ADC Synthesis (3) PROTAC Synthesis (7) Azide (12) Alkynes (14)
Oligonucleotides:	Adenosine (51) Guanosine (1) Nucleotide Analogs (4) Rat Pre-designed siRNA Sets (5) Adenine (9) Phospholipids (1) Other Phosphoramidite (3) Adenine Nucleotide (3) Guanine (6) siRNAs (21) Aptamers (1) Nucleoside Analogs (88) Uridine (8) Inosine (6) Cationic Lipids (1) Cytosine (1) Mouse Pre-designed siRNA Sets (5) Human Pre-designed siRNA Sets (11) Uracil (1) Phosphoramidites (20)

1460

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

MCE Kits

Inhibitory Antibodies

156

Natural
Products

202

Isotope-Labeled Compounds

Antibodies

Click Chemistry

135

Oligonucleotides

GMP Molecules

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W008296

NH2-C6-NH-Boc	PROTAC Linkers	Cancer
NH2-C6-NH-Boc is a PROTAC linker which refers to the alkyl/ether composition. NH2-C6-NH-Boc can be used in the synthesis the Mcl-1 inhibitor based on PROTAC .

HY-176444

CDK2 degrader 6	Molecular Glues CDK	Cancer
CDK2 degrader 6 is an orally active and potent CDK2 molecular glue degrader with a DC₅₀ of 46.5 nM. CDK2 degrader 6 binds to cereblon and CDK2 to induce ubiquitination and subsequent proteasomal degradation of CDK2. CDK2 degrader 6 modulates cell cycle in breast cancer cells. CDK2 degrader 6 reduces proliferation of breast cancer cells. CDK2 degrader 6 exhibits in vivo antitumor activity in gastric cancer mouse models. CDK2 degrader 6 can be used for the research of breast cancer, gastric cancer .

HY-157913

PKM2-IN-6	Pyruvate Kinase Apoptosis	Cancer
PKM2-IN-6 (compound 7d) is a potent and orally active PKM2 inhibitor with an IC₅₀ value of 23 nM. PKM2-IN-6 induces apoptosis and cell cycle arrest at G2 phase. PKM2-IN-6 reduces the level of PKM1 and PKM2 at the mRNA level. PKM2-IN-6 shows anticancer activity and has the potential for the research of triple-negative breast cancer .

HY-107198

*(2S)-6-Prenylnaringenin* 1 Publications Verification	GABA Receptor	Neurological Disease
(2S)-6-Prenylnaringenin is the most efficient compound in forebrain. (2S)-6-Prenylnaringenin acts as a GABA_A positive allosteric modulator at α+β- binding interface .

HY-130486

NH2-PEG6-Boc	PROTAC Linkers ADC Linker	Cancer
NH2-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . NH2-PEG6-Boc is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-117026

LKY-047 1 Publications Verification	Cytochrome P450	Metabolic Disease Inflammation/Immunology
LKY-047, a Decursin derivative, is a potent and selective reversible competitive cytochrome P45022J2 (CYP2J2) inhibitor with an IC₅₀ of 1.7 μM. LKY-047 is inactive against other human P450s, such as CYPs 1A2, 2A6, 2B6, 2C8, 2C9, 2C19, 2D6, 2E1, and 3A .

HY-22024

5-Hydroxyflavone 2 Publications Verification 5-OH-Flavone	Cytochrome P450	Others
5-Hydroxyflavone (5-OH-Flavone) is a flavonoid compound that undergoes oxidation-mediated conversion to 5,7-dihydroxyflavone and 5,6,7-trihydroxyflavone by human cytochrome P450 enzymes .

HY-101955A

*(2R,6R)-Hydroxynorketamine hydrochloride* (2R,6R)-HNK hydrochloride	Drug Metabolite	Neurological Disease
(2R,6R)-Hydroxynorketamine ((2R,6R)-HNK) hydrochloride is an active ketamine metabolite with no NMDAR binding activity. (2R,6R)-Hydroxynorketamine hydrochloride rescues impaired dorsal hippocampal long-term potentiation and restores robust long-term potentiation in the hippocampal SC-CA1 pathway. (2R,6R)-Hydroxynorketamine hydrochloride can be used for research on depression .

HY-130240

GCN2-IN-6 3 Publications Verification	Eukaryotic Initiation Factor (eIF)	Cancer
GCN2-IN-6 (Compound 6d) is a potent, and orally available GCN2 inhibitor confirmed by in-house enzymatic (IC₅₀ of 1.8 nM) and cellular assays (IC₅₀ of 9.3 nM). GCN2-IN-6 is also a eIF2α kinase PERK inhibitor with an IC₅₀ of 0.26 nM (in enzymatic assay) and 230 nM (in cells) . GCN2-IN-6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W017100

2-Hydroxy-6-methoxybenzoic acid 6-Methoxysalicylic acid	Drug Derivative	Neurological Disease
2-Hydroxy-6-methoxybenzoic acid (6-Methoxysalicylic acid) is an orally active derivative of Salicylic acid (HY-B0167). 2-Hydroxy-6-methoxybenzoic acid can be isolated from the plant Brickellia veronicifolia. 2-Hydroxy-6-methoxybenzoic acid has analgesic properties .

HY-128147

MetAP-2-IN-6	MetAP	Metabolic Disease Cancer
MetAP-2-IN-6 (4-(4-bromophenyl)-1H-1,2,3-triazole) is a MetAP2 inhibitor. MetAP-2-IN-6 can be used for research in conditions mediated by angiogenesis .

HY-101955

*(2S,6S)-Hydroxynorketamine hydrochloride* (2S,6S)-HNK hydrochloride	mTOR nAChR	Neurological Disease
(2S,6S)-Hydroxynorketamine hydrochloride is a neurorelaxant with potential antidepressant and analgesic effects. (2S,6S)-Hydroxynorketamine hydrochloride can activate the mTOR pathway, increase the phosphorylation level of downstream targets, and antagonize α7-nicotinic acetylcholine receptor (nAChR) to exert neuroactive properties .

HY-W008079

*(S)-2-Amino-6-((tert-butoxycarbonyl)amino)hexanoic acid*	Amino Acid Derivatives	Others
(S)-2-Amino-6-((tert-butoxycarbonyl)amino)hexanoic acid is a lysine derivative .

HY-135560

Nicotelline Nicotellin	Cytochrome P450	Neurological Disease
Nicotelline (Nicotellin) is a nicotine-related alkaloid, as well as a weak inhibitor of human cDNA-expressed cytochrome P-450 2A6 (CYP2A6). CYP2A6 mediates coumarin 7-hydroxylation, while Nicotelline fails to exhibit inhibition at 300 μM. Nicotelline can be used as a tracer and biomarker of particulate matter (PM) derived from tobacco smoke .

HY-137756

JAK2-IN-6 1 Publications Verification	JAK	Cancer
JAK2-IN-6, a multiple-substituted aminothiazole derivative, is a potent and selective JAK2 inhibitor with an IC₅₀ of 22.86 μg/mL. JAK2-IN-6 shows no activity against JAK1 and JAK3. JAK2-IN-6 has anti-proliferative effect against cancer cells .

HY-W089538

2-Ethyl-6-methylphenol	Bacterial	Infection
2-Ethyl-6-methylphenol, an alkylphenol, is isolated form the tumorigenic neutral subfraction of cigarette smoke condensate. 2-Ethyl-6-methylphenol exhibits insecticidal and bactericidal activities .

HY-Y0038

2-Bromo-6-methoxynaphthalene	Trk Receptor	Cancer
2-Bromo-6-methoxynaphthalene is an active intermediate in the production of anti-inflammatory agents like Naproxen and Nabumetone by Heck reaction. 2-Bromo-6-methoxynaphthalene has potential anti-inflammatory properties and Tyrosine-protein inhibitor properties. 2-Bromo-6-methoxynaphthalene can be used for the research of cancer .

HY-D2527

Biotin-PEG4-amide-PEG2-C6-Cl	Biochemical Assay Reagents	Others
Biotin-PEG4-amide-PEG2-C6-Cl is a biotinylated PEG4-amide-PEG2-C6-Cl.

HY-172910

MTHFD2-IN-6	Methylenetetrahydrofolate Dehydrogenase (MTHFD)	Cancer
MTHFD2-IN-6 (compound 41) is a potent and selective MTHFD2 inhibitor. MTHFD2-IN-6 inhibits MTHFD1 and MTHFD2 with IC₅₀s of 19.05 and 1.46 μM, respectively .

HY-W002593

2-Acetyl-6-bromopyridine	Biochemical Assay Reagents	Others
2-Acetyl-6-bromopyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 2-Acetyl-6-bromopyridine can be used to synthesize Schiff bases containing cycloalkyl substituents .

HY-W082430

CYP2A6-IN-2	Cytochrome P450	Neurological Disease
CYP2A6-IN-2 (compound 5) is a *CYP2A6* inhibitor. CYP2A6-IN-2 can be used in the study of nicotine dependence .

HY-W012626S

2-Ethyl-6-methylaniline-d13	Isotope-Labeled Compounds	Others
2-Ethyl-6-methylaniline-d₁₃ is the deuterium labeled 2-Ethyl-6-methylaniline .

HY-176941

ALK2-IN-6	TGF-β Receptor	Cancer
ALK2-IN-6 (Compound 14a) is a selective ALK2 inhibitor, with an IC₅₀ of 9 nM. ALK2-IN-6 can be used in the research of diffuse intrinsic pontine glioma .

HY-W128417S

4-(Dimethylamino)phenacyl bromide-13C2,d6 DmPABr-¹³C₂,d₆	Isotope-Labeled Compounds	Others
4-(Dimethylamino)phenacyl bromide- ¹³C₂,d₆ (DmPABr- ¹³C₂,d₆) is ¹³C-labeled 4-(Dimethylamino)phenacyl bromide (HY-W128417) .

HY-101506

2,4,6-Tribromophenyl caproate 1 Publications Verification	Fungal	Infection
2,4,6-Tribromophenyl caproate (2,4,6-tribromophenyl caproic acid ester) is an anti-fungal agent.

HY-N6989

Isoglycycoumarin	Cytochrome P450	Metabolic Disease
Isoglycycoumarin is a flavonoid isolated from the roots of Glycyrrhiza uralensis. Isoglycycoumarin is a highly selective probe for human cytochrome P450 2A6 (CYP2A6) .

HY-24238

DLCI-1	Cytochrome P450	Others
DLCI-1 is a potent and selective oral inhibitor of cytochrome P450 2A6 (CYP2A6) that markedly reduces nicotine self-administration in both male and female mice.

HY-155456

CYP2A6-IN-1	Cytochrome P450	Metabolic Disease
CD-6 is a flavonoid CYP2A6 inhibitor (IC₅₀: 1.566 μM). *CYP2A6* inhibits the metabolism of nicotine to cotinine, resulting in an increase in the amount of nicotine available in the blood, leading to increased smoking behavior. CD-6 mediates CYP2A6 inhibition and can be used in research on smoking cessation or smoking-related diseases .

HY-W040886

2-Bromo-6-nitrophenol	Drug Intermediate	Others
2-Bromo-6-nitrophenol is converted via 2-bromo-6-aminophenol to N-acetyl-2-bromo-6-aminophenol .

HY-Y1049

2-Amino-6-bromopyridine	Bacterial Drug Intermediate	Infection
2-Amino-6-bromopyridine is an intermediate. 2-Amino-6-bromopyridine is also a PqsR ligand with a K_d value of 6.8 μM in SPR assay. 2-Amino-6-bromopyridine shows weak antagonistic activity. 2-Amino-6-bromopyridine can be used in the synthesis of JAK2 inhibitors, MSK1 inhibitors, and in the research of Pseudomonas aeruginosa infection .

HY-Y1132

2-Amino-6-chlorobenzoic acid 6-Chloroanthranilic acid	Biochemical Assay Reagents	Others
2-Amino-6-chlorobenzoic acid is an autocoupling diazotization reagent used for spectrophotometric detection of nitrite ions in water. 2-Amino-6-chlorobenzoic acid exhibits good tolerance to various anions under acidic conditions. 2-Amino-6-chlorobenzoic acid is commonly used as a reagent in organic synthesis and analytical chemistry .

HY-145958

Sirt2-IN-6	Sirtuin	Cancer
Sirt2-IN-6 (compound 24a) potent and selective inhibitor of SIRT2, with an IC₅₀ of 0.815 μM. Sirt2-IN-6 can be used for the research of cancer .

HY-151533

PBRM1-BD2-IN-6	Epigenetic Reader Domain	Cancer
PBRM1-BD2-IN-6 is a potent PBRM1 bromodomain inhibitor with an IC₅₀ value of 0.22 μM. PBRM1-BD2-IN-6 shows antiproliferation activity. PBRM1-BD2-IN-6 has the potential for the research of PBRM1-dependent cancer .

HY-161885

SMARCA2-IN-6	Epigenetic Reader Domain	Cancer
SMARCA2-IN-6 is a SMARCA2 (also known as BRM) inhibitor, with IC₅₀s less than 5 nM for SMARCA2 and SMARCA4. SMARCA2-IN-6 inhibits KRT80 gene expression in H1299 cells (IC₅₀: 26 nM). SMARCA2-IN-6 inhibits proliferation in BRG1-mutant SKMEL5 cells (IC₅₀: 13 nM) .

HY-180491

*2-(3-(Azidomethyl)-2-formyl-6-methylphenoxy)acetic acid*	Biochemical Assay Reagents	Others
2-(3-(Azidomethyl)-2-formyl-6-methylphenoxy)acetic acid (Compound C1-4) is an azide reagent. 2-(3-(Azidomethyl)-2-formyl-6-methylphenoxy)acetic acid can be used in studies of protein fixed-point azidation .

HY-W649594

NR2F6 modulator-2	Orphan Nuclear Receptor	Inflammation/Immunology Cancer
NR2F6 modulator-2 (Compound I) is an autorepressed orphan nuclear receptor NR2F6 (Nuclear Receptor subfamily 2 group F member 6) modulator. NR2F6 modulator-2 can inhibits the recruitment of the bio-NSD1 peptide with an IC₅₀ of 2.0 equivalents of NR2F6. NR2F6 modulator-2 can be used for the researches of cancer and immunology .

HY-RS03454

CYP2A6 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CYP2A6 Human Pre-designed siRNA Set A contains three designed siRNAs for CYP2A6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CYP2A6 Human Pre-designed siRNA Set A CYP2A6 Human Pre-designed siRNA Set A

HY-RS13175

SLC2A6 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SLC2A6 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC2A6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SLC2A6 Human Pre-designed siRNA Set A SLC2A6 Human Pre-designed siRNA Set A

HY-Y0038R

2-Bromo-6-methoxynaphthalene (Standard)	Reference Standards Trk Receptor	Cancer
2-Bromo-6-methoxynaphthalene (Standard) is the analytical standard of 2-Bromo-6-methoxynaphthalene. This product is intended for research and analytical applications. 2-Bromo-6-methoxynaphthalene is an active intermediate in the production of anti-inflammatory agents like Naproxen and Nabumetone by Heck reaction. 2-Bromo-6-methoxynaphthalene has potential anti-inflammatory properties and Tyrosine-protein inhibitor properties. 2-Bromo-6-methoxynaphthalene can be used for the research of cancer .

HY-177271

PHD2-IN-6	HIF/HIF Prolyl-Hydroxylase	Inflammation/Immunology
PHD2-IN-6 (Example 89) is a HIF prolyl hydroxylase 2 (PHD2) inhibitor with an IC₅₀ of 31.6  nM. PHD2-IN-6 stimulates encoding erythropoietin (EPO) production. PHD2-IN-6 can be used for inflammatory diseases like inflammatory bowel disease (IBD) and rheumatoid arthritis research .

HY-P9804

*Anti-MERS-2E6* mAb** MERS-2E6; MERS Antibody-2E6	SARS-CoV	Infection
Anti-MERS-2E6 mAb (MERS-2E6; MERS Antibody-2E6), a human neutralizing antibody IgG1 (CHO expressed) that can compete for the binding of the virus Spike protein to the receptor (CD26), thereby inhibiting virus invasion into host cells.

HY-W009140S

2,4,6-Tribromophenol-d2	Isotope-Labeled Compounds	Others
2,4,6-Tribromophenol-d₂ is the deuterium labeled 2,4,6-Tribromophenol .

HY-176164

ALR2-IN-6	Aldose Reductase	Neurological Disease Metabolic Disease
ALR2-IN-6 (compound 9) is a potent and competitive ALR2 inhibitor with a K_i of 0.064 μM. ALR2-IN-6 can be used in the study of neuropathy, retinopathy, and nephropathy .

HY-W089538R

2-Ethyl-6-methylphenol (Standard)	Reference Standards Bacterial	Infection
2-Ethyl-6-methylphenol, an alkylphenol, is isolated form the tumorigenic neutral subfraction of cigarette smoke condensate. 2-Ethyl-6-methylphenol exhibits insecticidal and bactericidal activities .

HY-174274

ERK2-IN-6	ERK	Cancer
ERK2-IN-6 (Compound 20) is a highly selective ERK1/2 inhibitor with an IC₅₀ value of 7.9 nM for ERK2. ERK2-IN-6 inhibits the proliferation of BRAF ^V600E mutant cells (IC₅₀=250 nM in A375 cells). ERK2-IN-6 is promising for research of solid tumors, such as BRAF-mutated melanoma .

HY-CE00186

*(2S,6R,10R)-Trimethyl-hendecanoyl-CoA* (2S,6R,10R)-Trimethyl-hendecanoyl-coenzyme A	Biochemical Assay Reagents	Others
(2S,6R,10R)-Trimethyl-hendecanoyl-CoA ((2S,6R,10R)-Trimethyl-hendecanoyl-coenzyme A) is a fatty acyl-CoA.

HY-115866

COX-2-IN-6	COX	Cancer
COX-2-IN-6 (compound 10) is an orally active, gut-restricted and selective cyclooxygenase-2 (COX-2) inhibitor for colorectal Chemoprevention of cancer. COX-2-IN-6 selectively targets COX-2 with an IC₅₀ of 0.84 μM and a Ki of 69 nM. COX-2-IN-6 also inhibits COX-2-driven PGE2 synthesis with an IC₅₀ of 0.60 μM .

HY-151444

LRRK2-IN-6	LRRK2	Neurological Disease
LRRK2-IN-6 (compound 22) is a potent, orally active, selective leucine rich repeat protein kinase 2 gene (LRRK2) inhibitor with IC₅₀ values of 4.6 and 49 μM for GS LRRK2 and WT LRRK2, respectively. LRRK2-IN-6 inhibits LRRK2 Ser1292 and Ser925 autophosphorylation. LRRK2-IN-6 can cross the blood-brain barrier .

HY-W768482

2-Amino-6-hydroxypyrimidin-4(1H)-one-13C2 2-Amino-6-hydroxy-1H-pyrimidin-4-one-¹³C₂; 2-Amino-4,6-dihydroxypyrimidine-¹³C₂	Isotope-Labeled Compounds	Others
2-Amino-6-hydroxypyrimidin-4(1H)-one- ¹³C₂ (2-Amino-6-hydroxy-1H-pyrimidin-4-one- ¹³C₂) is the ¹³C-labeled 2-Amino-6-hydroxypyrimidin-4(1H)-one (HY-Y0559).

HY-W039272

2-Thio-6-azauridine	Biochemical Assay Reagents	Others
2-Thio-6-azauridine is a biochemical assay reagent.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-13765

6-Thioguanine Maximum Cited Publications 13 Publications Verification Thioguanine; 2-Amino-6-purinethiol	Infection Natural Products Classification of Application Fields Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification Cancer	SARS-CoV Deubiquitinase DNA Methyltransferase Autophagy Apoptosis Endogenous Metabolite
6-Thioguanine (Thioguanine; 2-Amino-6-purinethiol) is an anti-leukemia and immunosuppressant agent, acts as an inhibitor of SARS and MERS coronavirus papain-like proteases (PLpros) and also potently inhibits USP2 activity, with IC₅₀s of 25 μM and 40 μM for Plpros and recombinant human USP2, respectively.

HY-111832

*1,2,3,6-Tetragalloylglucose* TeGG	other families Classification of Application Fields Phenols Polyphenols Metabolic Disease Plants Disease Research Fields Source Classification	UGT
1,2,3,6-Tetragalloylglucose (TEgG) is a competitive inhibitor of UDP-glucuronyltransferase UGT1A1, targeting the competitive substrate binding site of UGT1A1. 1,2,3,6-Tetragalloylglucose inhibits UGT1A1-mediated β-estradiol 3-glucuronidation and SN-38 glucuronidation with IC₅₀ of 6.01 μM and 4.31 μM, respectively, and binds to UGT1A1 with K_i of 3.55 μM. 1,2,3,6-Tetragalloylglucose also induces tumor cell apoptosis, inhibit cell proliferation, activates caspase-3 and induces DNA fragmentation in HL-60 cells. 1,2,3,6-Tetragalloylglucose also inhibits HIV integrase and reverse transcriptase, and inhibits HCV protease .

HY-W010832

Uridine-5'-diphosphate disodium salt 2 Publications Verification	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	P2Y Receptor DNA/RNA Synthesis Endogenous Metabolite
Uridine-5'-diphosphate disodium salt is a potent, selective *P2Y₆* receptor native agonist (EC₅₀=300 nM; pEC₅₀=6.52 for human P2Y₆ receptor). Uridine-5'-diphosphate disodium salt, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis .

HY-N0387

Rhynchophylline 2 Publications Verification	Uncaria rhynchophylla (Miq.) Miq. ex Havil. Alkaloids Classification of Application Fields Rubiaceae Other Diseases Plants Disease Research Fields Indole Alkaloids Source Classification	NF-κB
Rhyncholphylline is an alkaloid compound isolated from Uncaria rhynchophyllum. Rhyncholphylline is an EphA4 inhibitor. It has high biological activity and is widely used in anti-inflammatory, neuroprotective and other research. ^[2] .

HY-N0494

Gentiopicroside 4 Publications Verification Gentiopicrin	Gentiana scabra Bunge Iridoids Classification of Application Fields Terpenoids Gentianaceae Plants Inflammation/Immunology Disease Research Fields Source Classification	Cytochrome P450 HCV
Gentiopicroside, a naturally occurring iridoid glycoside, inhibits P450 activity, with an IC₅₀ and a K_i of 61 μM and 22.8 μM for CYP2A6; Gentiopicroside has anti-inflammatoryand antioxidative effects.

HY-107198

*(2S)-6-Prenylnaringenin* 1 Publications Verification	Flavonoids Humulus lupulus L. Flavonones Phenols Polyphenols Plants Moraceae Source Classification	GABA Receptor
(2S)-6-Prenylnaringenin is the most efficient compound in forebrain. (2S)-6-Prenylnaringenin acts as a GABA_A positive allosteric modulator at α+β- binding interface .

HY-N2425

Rhodiosin	Flavonols Flavonoids Classification of Application Fields Rhodiola rosea Linn. Crassulaceae Phenols Polyphenols Metabolic Disease Plants Rhodiola crenulata (HK. f. et.Thoms) H. Ohba Disease Research Fields Source Classification	Cholinesterase (ChE)
Rhodiosin is a double inhibitor of CYP2D6 and AChE, and can be isolated from Rhodiolis rhodiolis root. The IC₅₀ for CYP2D6 is 0.761 μM, and the K_i is 0.769 μM. Rhodiosin has antioxidant and neuroprotective activity and can regulate HIF-1α signaling pathway to protect the central nervous system

HY-N0598

Ginsenoside F1 1 Publications Verification 20(S)-Ginsenoside F1	Panax ginseng C. A. Meyer Triterpenes Classification of Application Fields Terpenoids Plants Endogenous metabolite Disease Research Fields Araliaceae Source Classification Cancer	Cytochrome P450 Endogenous Metabolite
Ginsenoside F1, an enzymatically modified derivative of Ginsenoside Rg1, demonstrates competitive inhibition of CYP3A4 activity and weaker inhibition of CYP2D6 activity.

HY-22024

5-Hydroxyflavone 2 Publications Verification 5-OH-Flavone	Structural Classification Monophenols Flavonoids other families Classification of Application Fields Flavones Phenols Plants Disease Research Fields Source Classification Cancer	Cytochrome P450
5-Hydroxyflavone (5-OH-Flavone) is a flavonoid compound that undergoes oxidation-mediated conversion to 5,7-dihydroxyflavone and 5,6,7-trihydroxyflavone by human cytochrome P450 enzymes .

HY-N5132

(-)-Fenchone	Structural Classification Other Monoterpenes Classification of Application Fields Terpenoids Other Diseases Umbelliferae Plants Vernonia Schreb. Disease Research Fields Source Classification	Cytochrome P450
(-)-Fenchone is a bicyclic monoterpene and serves as a substrate for human liver microsomal cytochrome P450 enzymes *CYP2A6* and *CYP2B6*. (-)-Fenchone is not metabolized by human CYP1A1, CYP1A2, CYP1B1, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP2E1, or CYP3A4 enzymes. (-)-Fenchone undergoes hydroxylation to produce 6-exo-hydroxyfenchone, 6-endo-hydroxyfenchone, and 10-hydroxyfenchone. During the metabolism of (-)-Fenchone, CYP2A6 may play a more important role than CYP2B6 .

HY-N1131

Triacetonamine 1 Publications Verification 2,2,6,6-Tetramethyl-4-piperidone	Tribulus terrester Linn. Alkaloids Piperidine Alkaloids Classification of Application Fields Zygophyllaceae Other Diseases Plants Disease Research Fields Source Classification	Others
Triacetonamine (2,2,6,6-Tetramethyl-4-piperidone) is used as an intermediate for the synthesis of pharmaceutical products, pesticides and photostabilizers for polymers. Triacetonamine has oral activity and can induce acute liver failure (ALF) in rats .

HY-N7136

α-Terpinyl acetate	Structural Classification Other Monoterpenes Classification of Application Fields Terpenoids Laurus nobilis L. Metabolic Disease Plants Lauraceae Disease Research Fields Source Classification	Environmental Pollutants Cytochrome P450
α-Terpinyl acetate is a monoterpene ester isolated from Laurus nobilis L. essential oil. α-Terpinyl acetate is a competitive P450 2B6 substrate which binding to the active site of P450 2B6 with a K_d value of 5.4 μM .

HY-W017100

2-Hydroxy-6-methoxybenzoic acid 6-Methoxysalicylic acid	Monophenols Securidaca inappendiculata Hassk. Ketones, Aldehydes, Acids Polygalaceae Phenols Plants Source Classification	Drug Derivative
2-Hydroxy-6-methoxybenzoic acid (6-Methoxysalicylic acid) is an orally active derivative of Salicylic acid (HY-B0167). 2-Hydroxy-6-methoxybenzoic acid can be isolated from the plant Brickellia veronicifolia. 2-Hydroxy-6-methoxybenzoic acid has analgesic properties .

HY-113359

Uridine 5'-diphosphate UDP	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	P2Y Receptor Endogenous Metabolite
Uridine 5'-diphosphate (UDP) is a *P2Y₆* receptor agonist with an EC₅₀ of 0.013 μM for human P2Y₆ receptor .

HY-B1233

Octodrine 2-Amino-6-methylheptane; 1,5-Dimethylhexylamine; 6-Methyl-2-heptylamine	Natural Products Classification of Application Fields Ranunculaceae Other Diseases Aconitum carmichaeli Debx. Plants Disease Research Fields Source Classification	Dopamine Receptor
Octodrine (2-Amino-6-methylheptane) is a central nervous stimulant that increases the uptake of dopamine and noradrenaline. Octodrine is found to increase the pain threshold, cardiac rate (positive chronotropic effect) and myocardial contractility (positive inotropic effect) .

HY-N2260

Cephaeline dihydrochloride 1 Publications Verification (-)-Cephaeline dihydrochloride; NSC 32944	Infection Alkaloids Monophenols other families Classification of Application Fields Phenols Plants Isoquinoline Alkaloids Disease Research Fields Source Classification	Cytochrome P450
Cephaeline dihydrochloride is a selective *CYP2D6* inhibtor with an IC₅₀ of 121 μM.

HY-N2129

N-Nornuciferine 1 Publications Verification	Cardiovascular Disease Alkaloids Structural Classification other families Classification of Application Fields Metabolic Disease Nelumbo nucifera Gaertn. Plants Isoquinoline Alkaloids Nymphaeaceae Disease Research Fields Source Classification	Cytochrome P450 Cholinesterase (ChE)
N-Nornuciferine is an orally active, blood-brain barrier-permeable *CYP2D6* inhibitor, with an IC₅₀ of 3.76 μM and a K_i of 2.34 μM against human *CYP2D6. N-Nornuciferine also acts as a BChE* inhibitor, showing an IC₅₀ of 5.6 μM in mice . N-Nornuciferine can be used in the research of neurological-related diseases .

HY-N6964

Quercetin 3-O-β-D-(6''-p-coumaroyl)glucopyranosyl(1→2)-α-L-rhamnopyranoside Quercetin-3-O-[2-O-(6-O-p-hydroxyl-E-coumaroyl)-D-glucosyl]-(1→2)-L-rhamnoside	Flavonols Structural Classification Flavonoids Ginkgoaceae Classification of Application Fields Phenols Polyphenols Metabolic Disease Plants Ginkgo biloba Disease Research Fields Source Classification	Drug Derivative
Quercetin 3-O-β-D-(6''-p-coumaroyl) glucopyranosyl (1→2)-α-L-rhamnopyranoside (Quercetin-3-O-[2-O-(6-O-p-hydroxyl-E-coumaroyl)-D-glucosyl]-(1→2)-L-rhamnoside) is a flavonoid glycoside present in Ginkgo biloba leaves, with antioxidant activity. Quercetin 3-O-β-D-(6''-p-coumaroyl) glucopyranosyl (1→2)-α-L-rhamnopyranoside serves as the major antioxidant component in Shuxuening Injection .

HY-W089538

2-Ethyl-6-methylphenol	Infection Monophenols other families Classification of Application Fields Phenols Plants Disease Research Fields Source Classification	Bacterial
2-Ethyl-6-methylphenol, an alkylphenol, is isolated form the tumorigenic neutral subfraction of cigarette smoke condensate. 2-Ethyl-6-methylphenol exhibits insecticidal and bactericidal activities .

HY-W077292

2,4,6-Trihydroxybenzoic acid	Classification of Application Fields Ketones, Aldehydes, Acids Phenols Polyphenols Endogenous metabolite Disease Research Fields Source Classification Cancer	CDK
2,4,6-Trihydroxybenzoic acid, the flavonoid metabolite, is a CDK inhibitor. 2,4,6-Trihydroxybenzoic acid can be used for the research of cancer .

HY-W038786

2,4,6-Trimethylphenol	Structural Classification Monophenols Classification of Application Fields Other Diseases Phenols Endogenous metabolite Disease Research Fields Source Classification	Environmental Pollutants Fluorescent Dye
2,4,6-Trimethylphenol is a probe compound shown to react mainly with organic matter ( ³DOM ^). 2,4,6*-Trimethylphenol is rapidly oxidized by singlet oxygen in aqueous solution .

HY-W005130

2,4,6-Trihydroxybenzaldehyde	Monophenols Animals Phenols	NF-κB
2,4,6-Trihydroxybenzaldehyde is an orally active NF- B inhibitor. 2,4,6-Trihydroxybenzaldehyde shows anti-tumor activity, anti-cancer cell proliferative activity and anti-obesity activity .

HY-13765R

6-Thioguanine (Standard) Thioguanine (Standard); 2-Amino-6-purinethiol (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Reference Standards SARS-CoV Deubiquitinase DNA Methyltransferase Autophagy Apoptosis Endogenous Metabolite
6-Thioguanine (Standard) is the analytical standard of 6-Thioguanine. This product is intended for research and analytical applications. 6-Thioguanine (Thioguanine; 2-Amino-6-purinethiol) is an anti-leukemia and immunosuppressant agent, acts as an inhibitor of SARS and MERS coronavirus papain-like proteases (PLpros) and also potently inhibits USP2 activity, with IC₅₀s of 25 μM and 40 μM for Plpros and recombinant human USP2, respectively.

HY-N9529

Kaempferol 3-O-(2′′-O-α-rhamnosyl-6′′-O-malonyl-β-glucoside)	Flavonols Flavonoids Classification of Application Fields Leguminosae Clitoria ternatea Linn. Other Diseases Phenols Polyphenols Plants Disease Research Fields Source Classification	Others
Kaempferol 3-O-(2′′-O-α-rhamnosyl-6′′-O-malonyl-β-glucoside) is a flavonoid glycoside compound .

HY-N16556

2',4',6'-Trihydroxydihydrochalcone 4'-O-glucoside	Structural Classification Flavonoids Plants Dihydrochalcones Dipterocarpaceae Source Classification	Others
2',4',6'-Trihydroxydihydrochalcone 4'-O-glucoside (Compound 45) is a phenolic compound. 2',4',6'-Trihydroxydihydrochalcone 4'-O-glucoside can be isolated from Shorea roxburghii. 2',4',6'-Trihydroxydihydrochalcone 4'-O-glucoside can be used in the research of Cyclophosphamide (HY-17420)-induced peripheral neuropathy .

HY-N1483

Guanfu base A	Cardiovascular Disease Alkaloids Classification of Application Fields Other Alkaloids Ranunculaceae Aconitum carmichaeli Debx. Plants Disease Research Fields Source Classification	Potassium Channel
Guanfu base A is an antiarrhythmic alkaloid isolated from Aconitum coreanum and is a potent noncompetitive *CYP2D6* inhibitor, with a K_i of 1.20 μM in human liver microsomes (HLMs) and a K_i of 0.37 μM for the human recombinant form (rCYP2D6). Guanfu base A is also a potent competitive inhibitor of CYP2D in monkey (K_i of 0.38 μM) and dog (K_i of 2.4 μM) microsomes . Guanfu base A also inhibits HERG channel current .

HY-N8382

Chalepensin	Structural Classification Natural Products Haloxylon ammodendron (C. A. Mey.) Bunge Amaranthaceae Plants Source Classification	Cytochrome P450 Parasite Insecticide
Chalepensin is a nematicide and CYP inhibitor. Chalepensin inhibits *CYP2A6, CYP1A1, CYP1A2, CYP2A13, CYP2C9, CYP2D6, CYP2E1, and CYP3A4* to varying degrees, with IC₅₀ values of 82.3 μM, 2.86 μM, 3.01 μM, 0.21 μM, 6.58 μM, 1.67 μM, 61.1 μM, and 61.7 μM, respectively. Chalepensin potently and selectively kills third-stage infective larvae of Strongyloides venezuelensis .

HY-W077292R

2,4,6-Trihydroxybenzoic acid (Standard)	Ketones, Aldehydes, Acids Phenols Polyphenols Endogenous metabolite Source Classification	Reference Standards CDK
2,4,6-Trihydroxybenzoic acid, the flavonoid metabolite, is a CDK inhibitor. 2,4,6-Trihydroxybenzoic acid can be used for the research of cancer .

HY-W144096

*Methyl 2,4,6-trihydroxybenzoate*	Classification of Application Fields Phenols Polyphenols Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification Cancer	Drug Metabolite
Methyl 2,4,6-trihydroxybenzoate is a metabolite of 2,4,6-trihydroxybenzoate and exhibits properties as an antioxidant, lipid lowering and anticancer activities .

HY-N1131B

Triacetonamine monohydrate 1 Publications Verification 2,2,6,6-Tetramethyl-4-piperidone monohydrate	Alkaloids Piperidine Alkaloids other families Classification of Application Fields Other Diseases Plants Disease Research Fields Source Classification	Others
Triacetonamine (2,2,6,6-Tetramethyl-4-piperidone) monohydrate is used as an intermediate for the synthesis of pharmaceutical products, pesticides and photostabilizers for polymers. Triacetonamine hydrochloride has oral activity and can induce acute liver failure (ALF) in rats .

HY-13938

Iretol 1 Publications Verification	Classification of Application Fields Phenols Polyphenols Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Iretol (2,4,6-trihydroxyanisole) is a a degradation product of a glucoside obtained from Iris Jorentina. Iretol is an intermediate in the synthesis of natural isoflavones, such as Tectorigenin, Irigenin and Caviunin .

HY-N6989

Isoglycycoumarin	Classification of Application Fields Leguminosae Coumarins Phenols Polyphenols Metabolic Disease Phenylpropanoids Plants Disease Research Fields Glycyrrhiza uralensis Fisch. Source Classification	Cytochrome P450
Isoglycycoumarin is a flavonoid isolated from the roots of Glycyrrhiza uralensis. Isoglycycoumarin is a highly selective probe for human cytochrome P450 2A6 (CYP2A6) .

HY-N1663

2',4',6'-Trimethoxyacetophenone 2,4,6-Trimethoxyphenyl methyl ketone	Natural Products Rutaceae Citrus medica L. Plants Source Classification	Others
2',4',6'-Trimethoxyacetophenone (2,4,6-Trimethoxyphenyl methyl ketone) is a Diterpenoids product that can be isolated from the herbs of Chloranthus elatior .

HY-N15572

*1,2,4,6-Tetra-O-galloyl-β-D-glucose*	Phenols Polyphenols Myrtaceae Plants Eucalyptus globulus Labill. Source Classification	SOD
1,2,4,6-Tetra-O-galloyl-β-D-glucose is an antioxidant found in Eucalyptus globulus. 1,2,4,6-Tetra-O-galloyl-β-D-glucose has significant superoxide dismutase (SOD)-like antioxidant activity (EC₅₀: 1.55 μM). 1,2,4,6-Tetra-O-galloyl-β-D-glucose can inhibit tyrosinase (IC₅₀: 0.59 mM) and hyaluronidase (IC₅₀: 0.68 mM). 1,2,4,6-Tetra-O-galloyl-β-D-glucose can be used in food antioxidants, cosmetics anti-melanogenesis and anti-allergy/anti-inflammatory research .

HY-N1868

*3-Prenyl-2,4,6-trihydroxybenzophenone*	Xanthones Guttiferae Phenols Plants Garcinia cowa Roxb. Source Classification	Others
3-Prenyl-2,4,6-trihydroxybenzophenone is a Xanthones product that can be isolated from the herbs of Garcinia cowa .

HY-N11706

β-Cedrene (+)-β-Cedrene	Structural Classification Terpenoids Sesquiterpenes Erythrina arborescensRoxb. Plants Compositae Source Classification	Fungal
β-Cedrene ((+)-β-Cedrene) is a sesquiterpene compound that can be isolated from Centaurea kotschyi var. kotschyi and Centaurea kotschyi var. decumbens, exhibiting antibacterial, anti-inflammatory, antispasmodic, tonic, diuretic, sedative, insecticidal, and antifungal activities. β-Cedrene is also a potent competitive inhibitor of the CYP2B6-mediatedbupropion hydroxylase, with a K_i value of 1.6 μM .

HY-N8132

2,4,6-Trichlorol-3-methyl-5-methoxy-phenol 1-O-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranoside	Natural Products Liliaceae Classification of Application Fields Plants Disease Research Fields Inflammation/Immunology Lilium brownie var. viridulum Source Classification	Reactive Oxygen Species (ROS)
2,4,6-Trichlorol-3-methyl-5-methoxy-phenol 1-O-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranoside is a chlorophenyl glycoside found in the bulbs of Lilium brownie var. viridulum. 2,4,6-Trichlorol-3-methyl-5-methoxy-phenol 1-O-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranoside exhibits weak inhibition of NO production in LPS-stimulated RAW 264.7 cells .

HY-W089538R

2-Ethyl-6-methylphenol (Standard)	Structural Classification Monophenols other families Phenols Plants Source Classification	Reference Standards Bacterial
2-Ethyl-6-methylphenol, an alkylphenol, is isolated form the tumorigenic neutral subfraction of cigarette smoke condensate. 2-Ethyl-6-methylphenol exhibits insecticidal and bactericidal activities .

HY-N13828

*1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole*	Alkaloids Rutaceae Murraya koenigii (L.) Spreng Carbazole Alkaloids Plants Indole Alkaloids Source Classification	Bacterial Interleukin Related
1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole (Compound 19) is a carbazole alkaloid that can be isolated from Murraya koenigii. 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole exhibits anti-inflammatory and antimicrobial activities. 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole can inhibit the production of pro-inflammatory cytokines TNF-α and IL-6 . 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole has IC₅₀ values of 10.9 μM and 95 μM for Bacillus cereus and Staphylococcus aureus, respectively. 1-Prenyl-2-methoxy-6-formyl-8-hydroxy-9H-carbazole can be used in the research of inflammatory and infectious diseases .

HY-W144096R

*Methyl 2,4,6-trihydroxybenzoate (Standard)*	Phenols Polyphenols Endogenous metabolite Source Classification	Drug Metabolite Reference Standards
Methyl 2,4,6-trihydroxybenzoate is a metabolite of 2,4,6-trihydroxybenzoate and exhibits properties as an antioxidant, lipid lowering and anticancer activities .

HY-N1671

2',5,6',7-Tetraacetoxyflavanone	Structural Classification Flavonoids Labiatae Flavonones Plants Medicago truncatula Gaertn. Source Classification	Others
2',5,6',7-Tetraacetoxyflavanone is an extract isolated from Scutellaria baicalensis. 2',5,6',7-Tetraacetoxyflavanone shows significant antibacterial activity against gram-positive bacteria. 2',5,6',7-Tetraacetoxyflavanone can be used to study the treatment of inflammatory diseases .

HY-N5132R

(-)-Fenchone (Standard)	Structural Classification Other Monoterpenes Terpenoids Umbelliferae Plants Vernonia Schreb. Source Classification	Reference Standards Others
(-)-Fenchone (Standard) is the analytical standard of (-)-Fenchone. This product is intended for research and analytical applications. (-)-Fenchone, a bicyclic monoterpene, is widely distributed in plants and found in essential oils from Foeniculum vulgare. (-)-Fenchone is oxidized to 6-endo-hydroxyfenchone, 6-exo-hydroxyfenchone and 10-hydroxyfenchone derivatives by CYP2A6 and CYP2B6 in human liver microsomes with CYP2A6 playing a more important role than CYP2B6 .

HY-N3867

*Ethyl 2,4,6-trihydroxybenzoate* Benzoic acid, 2,4,6-trihydroxy-, ethyl ester	other families Phenols Polyphenols Plants Celtis biondii Pamp. Source Classification	LXR
Ethyl 2,4,6-trihydroxybenzoate (Benzoic acid, 2,4,6-trihydroxy-, ethyl ester) is a Triterpenoids product that can be isolated from the herbs of Pueraria lobata .

HY-N0968

*1-Methyl-2-[(Z)-6-undecenyl]-4(1H)-quinolone*	Alkaloids Classification of Application Fields Evodia rutaecarpa (Juss.) Benth. Rutaceae Other Diseases Quinoline Alkaloids Plants Disease Research Fields Source Classification	Others
1-Methyl-2-[(Z)-6-undecenyl]-4(1H)-quinolone, as a colorless oil, is a quinolone alkaloid isolated from the fruit of Evodia rutaecarpa BENTHAM (Rutaceae) .

HY-N15063

*10-Hydroxyundeca-2,4,6,8-tetraynamide*	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Bacterial Fungal
10-Hydroxyundeca-2,4,6, 8-tetraynamide is a polyacetylene antibiotic. 10-Hydroxyundeca-2,4,6,8-tetraynamide has anti-Gram-positive bacteria, negative bacteria, yeast, fungus activity and cytotoxicity .

HY-W671745

*Entadamide A 2'-O-(6''-O-β-D-glucopyranosyl)-β-D-glucopyranoside*	Structural Classification Natural Products Petasites formosanus Kitam. Leguminosae Plants Source Classification	Others
Entadamide A 2'-O-(6''-O-β-D-glucopyranosyl)-β-D-glucopyranoside (MFLNH I) (compound 5) can be isolated from the seed kernel of Entada rheedei. Entada rheedei is a medicinal plant from Thailand that is used to suppress stomach pain .

HY-N12549

*4,2′,4′,6′-Tetramethoxychalcone*	Flavonoids Pseudognaphalium affine (D. Don) Anderberg Plants Compositae Other Flavonoids Source Classification	Others
4,2′,4′,6′-Tetramethoxychalcone is a flavonoids that can be isolated from Gnaphalium affine .

HY-N9721

*Methyl 8-hydroxy-3-(2-methoxy-2-oxoethyl)-6-methyl-9-oxo-9H-furo[3,4-b]chromene-1-carboxylate*	Polygalaceae Phenols Plants Polygala fallax Hemsl. Source Classification	Others
Methyl 8-hydroxy-3-(2-methoxy-2-oxoethyl)-6-methyl-9-oxo-9H-furo[3,4-b]chromene-1-carboxylate is a Phenols product that can be isolated from the roots of Polygala fallax .

HY-N9739

*(2S)-6,4'-Dihydroxy-7-methoxyflavan*	Flavonoids Dalbergia odorifera T. Chen Leguminosae Plants Other Flavonoids Source Classification	Others
(2S)-6,4'-Dihydroxy-7-methoxyflavan is a natural product .

HY-N15589

8-(6,7-Dihydroxy-3,7-dimethyl-2E-octenyloxy)psoralen	Structural Classification Citrus maxima (Burm.) Merr. Rutaceae Coumarins Phenylpropanoids Plants Source Classification	Interleukin Related Prostaglandin Receptor TNF Receptor
8-(6,7-Dihydroxy-3,7-dimethyl-2E-octenyloxy)psoralen is a compound found in Citrus grandis. 8-(6,7-Dihydroxy-3,7-dimethyl-2E-octenyloxy)psoralen has significant anti-inflammatory activity, which mainly works by inhibiting the secretion of inflammatory factors IL-1β, PGE2 and TNF-α. 8-(6,7-Dihydroxy-3,7-dimethyl-2E-octenyloxy)psoralen can be used in the study of inflammation .

Cat. No.	Product Name	Chemical Structure

HY-144427S

Vitamin E-13C2,d6
Vitamin E- ¹³C₂,d₆ is a ¹³C-labeled and deuterium labeled Vitamin E .

HY-76542S

Vitamin D2-d6
Vitamin D2-d₆ is the deuterium labeled Vitamin D2. Vitamin D2 (Ergocalciferol), drived from plant sources or dietary supplements, could be used as supplement of Vitamin D .

HY-B0365AS

Memantine-d6 hydrochloride
Memantine-d₆ (hydrochloride) is the deuterium labeled Memantine hydrochloride. Memantine (hydrochloride) (D-145 (hydrochloride)) is a moderate affinity, uncompetitive NMDA receptor antagonist, inhibit CYP2B6 and CYP2D6 with K_is of 0.51 nM and 94.9 μM, respectively .

HY-N1131S

Triacetonamine-d17
Triacetonamine-d17 (2,2,6,6-Tetramethyl-4-piperidone-d17) is the deuterium labeled Triacetonamine. Triacetonamine has oral activity and can induce acute liver failure (ALF) in rats .

HY-128669S

Abemaciclib metabolite M2-d6
Abemaciclib metabolite M2-d₆ is the deuterium labeled Abemaciclib metabolite M2. Abemaciclib metabolite M2 (LSN2839567) is a metabolite of Abemaciclib, acts as a potent CDK4 and CDK6 inhibitor, with IC₅₀s in the range of 1-3 nM. Anti-cancer activity .

HY-W714356

N-6-Methyl-2-deoxyadenosine-d3
N-6-Methyl-2-deoxyadenosine-d3 is the deuterium labeled N-6-Methyl-2-deoxyadenosine (HY-W011725). N-6-Methyl-2-deoxyadenosine is an adenine nucleoside analogue .

HY-113359AS2

Uridine 5'-diphosphate-13C9,15N2 dilithium
Uridine 5'-diphosphate- ¹³C₉, ¹⁵N₂ dilithium is ¹³C and ¹⁵N-labeled Uridine 5'-diphosphate (HY-113359). Uridine 5'-diphosphate is a *P2Y₆* receptor agonist with an EC₅₀ of 0.013 μM for human P2Y₆ receptor.

HY-W012626S

2-Ethyl-6-methylaniline-d13
2-Ethyl-6-methylaniline-d₁₃ is the deuterium labeled 2-Ethyl-6-methylaniline .

HY-W128417S

4-(Dimethylamino)phenacyl bromide-13C2,d6
4-(Dimethylamino)phenacyl bromide- ¹³C₂,d₆ (DmPABr- ¹³C₂,d₆) is ¹³C-labeled 4-(Dimethylamino)phenacyl bromide (HY-W128417) .

HY-150848S

2,3,6-Trichloroanisole-d3
2,3,6-Trichloroanisole-d₃ is the deuterium labeled 2,3,6-Trichloroanisole .

HY-Y1359S

2-Methylimidazole-d6
2-Methylimidazole-d₆ is the deuterium labeled 2-Methylimidazole .

HY-W243018S

*1,2:5,6-Di-O-isopropylidene-a-D-glucofuranose-1,2,3,4,5,6-13C6*
1,2:5,6-Di-O-isopropylidene-a-D-glucofuranose-1,2,3,4,5,6- ¹³C₆ is the ¹³C labeled 1,2:5,6-Di-O-isopropylidene-a-D-glucofuranose-1,2,3,4,5,6 .

HY-W105506S

Dimethylpropiothetin hydrochloride-d6
(2-Carboxyethyl)dimethylsulfonium-d₆ chloride is the deuterium labeled (2-Carboxyethyl)dimethylsulfonium chloride .

HY-W128333S

2,3,6-Trimethylphenol-d11
2,3,6-Trimethylphenol-d₁₁ is the deuterium labeled 2,3,6-Trimethylphenol .

HY-15328

25-Hydroxy VD2-d6
25-Hydroxy VD2-d₆ is the deuterium labeled 25-Hydroxy VD2.

HY-W414826S

2,4,6-Trichlorobiphenyl-2′,3′,4′,5′,6′-d5
2,4,6-Trichlorobiphenyl-2′,3′,4′,5′,6′-d₅ is the deuterium labeled 2,4,6-Trichloro-1,1'-biphenyl .

HY-Y0194S

2-Aminohexane-d6
2-Aminohexane-d₆ is the deuterium labeled 2-Aminohexane .

HY-W700648

Zolpidem phenyl-4-carboxylic acid-d6
Zolpidem phenyl-4-carboxylic acid-d₆ is the deuterium labeled 4-(3-(2-(Dimethylamino)-2-oxoethyl)-6-methylimidazo[1,2-a]pyridin-2-yl)benzoic acid (HY-W700647).

HY-W002004S1

4-Amino-TEMPO-d17

4-Amino-TEMPO-d₁₇ (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-d₁₇) is the deuterium labeled 4-Amino-TEMPO (HY-W002004). 4-Amino-TEMPO (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl) is a stable nitroxide radical and N-nucleophile based on TEMPO. 4-Amino-TEMPO has superoxide dismutase-mimetic activity, can protect cells from oxidative damage, and has radioprotective effects. 4-Amino-TEMPO is widely used in fields such as biomedicine, materials science, and industrial production. 4-Amino-TEMPO can be used as a spin label to detect free radicals, an oxidation catalyst in industrial production, and an antioxidant stabilizer for polymers, among others .

HY-B1874S

Metoxuron-d6
Metoxuron-d₆ is the deuterium labeled Methyl 3,6-dichloro-2-methoxybenzoate .

HY-W009140S

2,4,6-Tribromophenol-d2
2,4,6-Tribromophenol-d₂ is the deuterium labeled 2,4,6-Tribromophenol .

HY-W768482

2-Amino-6-hydroxypyrimidin-4(1H)-one-13C2
2-Amino-6-hydroxypyrimidin-4(1H)-one- ¹³C₂ (2-Amino-6-hydroxy-1H-pyrimidin-4-one- ¹³C₂) is the ¹³C-labeled 2-Amino-6-hydroxypyrimidin-4(1H)-one (HY-Y0559).

HY-W013113S

*Bis(2,2,6,6-tetramethylpiperidin-4-yl) decanedioate-d24*
Bis(2,2,6,6-tetramethylpiperidin-4-yl) decanedioate-d₂₄ (Sebacic acid bis(2,2,6,6-tetramethyl-4-piperidyl) ester-d₂₄) is deuterium labeled BTMPS .

HY-W038786S

2,4,6-Trimethylphenol-d11
2,4,6-Trimethylphenol-d₁₁ is the deuterium labeled 2,4,6-Trimethylphenol . 2,4,6-Trimethylphenol is a probe compound shown to react mainly with organic matter (3DOM). 2,4,6*-Trimethylphenol is rapidly oxidized by singlet oxygen in aqueous solution .

HY-W334800S2

*(2S,6S)-2,6-Diaminoheptanedioic acid-13C7*
(2S,6S)-2,6-Diaminoheptanedioic acid- ¹³C₇ (L-threo-2,6-Diaminopimelic acid- ¹³C₇) is ¹³C-labeled (2S,6S)-2,6-diaminoheptanedioic acid (HY-W334800).

HY-W334800S1

*(2S,6S)-2,6-Diaminoheptanedioic acid-15N2*
(2S,6S)-2,6-Diaminoheptanedioic acid- ¹⁵N₂ (L-threo-2,6-Diaminopimelic acid- ¹⁵N₂) is ¹⁵N labeled (2S,6S)-2,6-diaminoheptanedioic acid (HY-W334800).

HY-W097929S

2,4,6-Trichloroanisole-d5
2,4,6-Trichloroanisole-d₅ is the deuterium labeled 2,4,6-Trichloroanisole .

HY-W091728S

2,4,6-Tribromoanisole-d5
2,4,6-Tribromoanisole-d₅ is the deuterium labeled 2,4,6-Tribromoanisole .

HY-B1912S1

Amidosulfuron-13C2,d6
Amidosulfuron- ¹³C₂,d₆ is the ¹³C- and deuterium labeled Amidosulfuron .

HY-143992S

Maytansinoid DM4 impurity 2-d6
Maytansinoid DM4 impurity 2-d₆ is the deuterium labeled Maytansinoid DM4 impurity 2 .

HY-W127515S

trans-2,cis-6-Nonadienal-13C2

trans-2,cis-6-Nonadienal- ¹³C₂ is ¹³C labeled trans-2,cis-6-Nonadienal (HY-W127515). Trans-2, cis-6-NonadienalIt is an organic compound belonging to aldehydes. It has a strong, pungent smell and is commonly found in a variety of foods, including fruits and vegetables. Trans-2, cis-6-NonadienalIt has a variety of applications in the flavor and fragrance industry, especially as a fragrance agent in products such as perfume, cologne and air fresheners. In addition, it can also be used as an intermediate in the synthesis of various chemicals and drugs.

HY-W129420S

*N,N'-(Hexane-1,6-diyl)bis(N-(2,2,6,6-tetramethylpiperidin-4-yl)formamide)-d24*
N,N'-(Hexane-1,6-diyl)bis(N-(2,2,6,6-tetramethylpiperidin-4-yl)formamide)-d₂₄ is deuterium labeled N,N'-(Hexane-1,6-diyl)bis(N-(2,2,6,6-tetramethylpiperidin-4-yl)formamide) .

HY-W130532S

2,4,6-Trifluorbenzyl alcohol-d2
2,4,6-Trifluorbenzyl alcohol-d₂ is the deuterium labeled 2,4,6-Trifluorbenzyl alcohol .

HY-W334800S

*(2S,6S)-2,6-Diaminoheptanedioic acid-13C7,15N2*
(2S,6S)-2,6-Diaminoheptanedioic acid- ¹³C₇, ¹⁵N₂ (L-threo-2,6-Diaminopimelic acid- ¹³C₇, ¹⁵N₂) is ¹³C and ¹⁵N-labeled (2S,6S)-2,6-diaminoheptanedioic acid (HY-W334800).

HY-150987S

2,2',6-Trichloro bisphenol A-d11
2,2',6-Trichloro bisphenol A-d₁₁ is the deuterium labeled 2,2',6-Trichloro bisphenol A .

HY-W704658

2,4,6-Trimethylbenzeneamine-d11
2,4,6-Trimethylbenzeneamine-d₁₁ is the deuterium labeled 2,4,6-Trimethylaniline (HY-W007785).

HY-144150S

Pelubiprofen impurity 2-13C2,d6
Pelubiprofen impurity 2- ¹³C₂,d₆ is the ¹³C- and deuterium labeled Pelubiprofen impurity 2 .

HY-W703429S

2,3,6,7-Tetrachloro-naphthalene-13C10
2,3,6,7-Tetrachloro-naphthalene- ¹³C₁₀ is ¹³C labeled 2,3,6,7-Tetrachloronaphthalene .

HY-132644S1

3-Demethylthiocolchicine-13C2,d6
3-Demethyl Thiocolchicine--- ¹³C₂,d₆ is ¹³C and deuterated labeled 3-Demethyl Thiocolchicine-.

HY-156269S

*2-(2-Furanyl)-6-methylpyrazine-d3*
2-(2-Furanyl)-6-methylpyrazine-d₃ is deuterated labeled 2-(2-Furanyl)-6-methylpyrazine.

HY-W104549S

3,6-Dichloro-2-hydroxybenzoic acid-13C6
3,6-Dichloro-2-hydroxybenzoic acid- ¹³C₆ is the ¹³C labeled 3,6-Dichloro-2-hydroxybenzoic acid .

HY-166933S

*1,2,3,6,7-Pentachloro-naphthalene-13C10*
1,2,3,6,7-Pentachloro-naphthalene- ¹³C₁₀ is ¹³C labeled 1,2,3,6,7-Pentachloro-naphthalene .

HY-W748961

*Norethindrone Acetate-2,2,4,6,6,10-d6*
Norethindrone Acetate-2,2,4,6,6,10-d₆ is deuterated labeled Norethindrone Acetate-2,2,4,6,6,10.

HY-143943S

Felodipine 3,5-dimethyl ester-13C2,d6
Felodipine 3,5-dimethyl ester- ¹³C₂,d₆ is the ¹³C- and deuterium labeled Felodipine 3,5-dimethyl ester .

HY-146939S

*CER7-2’R,6R-d9*
CER7-2’R,6R-d₉ is deuterium labeled CER7-2’R,6R.

HY-146940S

*CER7-2’S,6R-d9*
CER7-2’S,6R-d₉ is deuterium labeled CER7-2’S,6R.

HY-W748299

*1,2,3,6,7,8-Hexachloro-dibenzofuran-13C12*
1, 2, 3, 6, 7, 8-Hexachloro-dibenzofuran- ¹³C₁₂ is ¹³C labeled 1, 2, 3, 6, 7, 8-Hexachloro-dibenzofuran .

HY-W753344

2-(2,6-Dichlorophenoxy)-N-phenylacetamide-13C6
2-(2,6-Dichlorophenoxy)-N-phenylacetamide- ¹³C₆ is the ¹³C-labeled 2-(2,6-Dichlorophenoxy)-N-phenylacetamide (HY-W713396).

HY-150667S

2-Amino-6-(3-methoxy-anilino)purine-d3
2-Amino-6-(3-methoxy-anilino)purine-d₃ is the deuterium labeled 2-Amino-6-(3-methoxy-anilino)purine .

HY-W071201S

N,N-Dimethyl-2-sulfamoylnicotinamide-d6
N,N-Dimethyl-2-sulfamoylnicotinamide-d₆ (2-Aminosulfonyl-N,N-dimethylnicotinamide-d₆) is deuterium labeled N,N-Dimethyl-2-sulfamoylnicotinamide .

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-17356G

Fenofibrate	Cytochrome P450 PPAR Autophagy	Cardiovascular Disease
Fenofibrate (GMP) is Fenofibrate (HY-17356) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Fenofibrate is a selective PPARα agonist with an EC₅₀ of 30 μM. Fenofibrate also inhibits human cytochrome P450 isoforms, with IC₅₀s of 0.2, 0.7, 9.7, 4.8 and 142.1 μM for CYP2C19, *CYP2B6, CYP2C9, CYP2C8, and CYP3A4*, respectively.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks