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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
374 Results for "
3-hydroxy
" in MedChemExpress (MCE) Product Catalog:
Products (374)
374 Results for "3-hydroxy" in MCE Product Catalog:
81
81 Publications Verification
Cat. No.: HY-17379
CAS No.: 134523-03-8
Synonyms: CI-981; Atorvastatin hemicalcium
Research Areas:
Atorvastatin hemicalcium salt (CI-981) is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, with blood-brain barrier permeability. Atorvastatin hemicalcium salt has the ability to effectively decrease blood lipids. Atorvastatin hemicalcium salt inhibits human SV-SMC proliferation and invasion with IC50s of 0.39 μM and 2.39 μM, respectively [3] .
17
Target:
Research Areas:
Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
8
Research Areas:
SR12813 (GW 485801) is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, with an IC50 value of 0.85 μM . SR12813 is also an efficient agonist of human pregnane X receptor (hPXR). SR12813 can strongly bind to hPXR but not to mouse PXR (mPXR) [3].
3
3 Cited Publications
Synonyms: 3-hydroxy-4-methoxycinnamic acid
2
2 Cited Publications
Synonyms: 3-hydroxy-DL-kynurenine
Category:
Monophenols Neurological Disease Ketones, Aldehydes, Acids Phenols Endogenous metabolite Disease Research Fields
Target:
2
2 Cited Publications
Cat. No.: HY-P72228
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HMGCR; 3-hydroxy-3-Methylglutaryl Coenzyme A Reductase; 3-hydroxy-3-Methylglutaryl-CoA Reductase; hydroxymethylglutaryl-CoA Reductase (NADPH); 3-hydroxy-3-Methylglutaryl-Coenzyme A Reductase; Alternative Protein HMGCR; HMG-CoA Reductase; LGMDR28; 3-Hydrox
Species:
Human
Source:
E. coli
2
2
2 Cited Publications
Synonyms: GYKI-53773; LY-300164
Research Areas:
Talampanel (LY300164) is an orally and selective α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptor antagonis with anti-seizure activity . Talampanel (IVAX) has neuroprotective effects in rodent stroke models . Talampanel attenuates caspase-3 dependent apoptosis in mouse brain .
2
2 Cited Publications
Category:
Natural Products Animal Marine natural products Other marine organisms Disease Research Fields Cancer
Target:
1
Category:
Asclepiadaceae Extract Plant Monophenols Periploca sepium Bunge Extract Ketones, Aldehydes, Acids Phenols
Target:
1
1 Cited Publications
Cat. No.: HY-W008467
CAS No.: 16820-18-1
Target:
Research Areas:
1
1 Cited Publications
Synonyms: LY300168 hydrochloride
Target:
Research Areas:
GYKI 53655 (LY300168) hydrochloride is an α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) antagonist.
1
1 Cited Publications
Cat. No.: HY-N0468
CAS No.: 63279-13-0
Category:
Plant Terpenoids Metabolic Disease Diterpenoids Other Families Extract Disease Research Fields Sweeteners Food Research
Target:
Category:
Plant Monophenols Ketones, Aldehydes, Acids Scrophulariaceae Extract Phenols Disease Research Fields Inflammation/Immunology Scrophularia ningpoensis Hemsl. Extract
Target:
Cat. No.: HY-W002339
CAS No.: 1121-25-1
Category:
Astragalus membranaceus var. mongholicus (Bunge)P.K.Hsiao Extract Alkaloids Leguminosae/Fabaceae Extract Plant Other Diseases Pyridine Alkaloids Other Families Extract Disease Research Fields
Target:
Synonyms: CGP52421
3-Hydroxy Midostaurin (CGP 52421), a metabolite of PKC412, effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC50s of approximately 132 nM and 9.8 μM in culture medium and plasma, respectively. 3-Hydroxy Midostaurin is less selective but more cytotoxic than PKC412 .
Cat. No.: HY-W342499
CAS No.: 55682-83-2
Synonyms: Methyl 3-hydroxytetradecanoate; 3-OH PAME; Methyl 3-hydroxymyristate
Target:
Research Areas:
3-Hydroxy myristic acid methyl ester (Methyl 3-hydroxytetradecanoate) is the quorum-sensing signal molecule (quormone), which regulates the virulence of Ralstonia solanacearum .
Target:
Research Areas:
3-Hydroxy agomelatine-d3 is a deuterium labeled 3-Hydroxy agomelatine. 3-Hydroxy agomelatine is a 5-HT2C receptor antagonist with an IC50 of 3.2 μM and a Ki of 1.8 μM .
Target:
Research Areas:
Methyl 3-hydroxyoctanoate (3-Hydroxy octanoic acid methyl ester) is an ester. Methyl 3-hydroxyoctanoate can be isolated from Pineapple .
Cat. No.: HY-141639
CAS No.: 40165-89-7
Target:
Research Areas:
3-Hydroxyheptadecanoic acid is a type of 3-hydroxy acid that can be used as a chemical marker for endotoxins .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
