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ARG

" in MedChemExpress (MCE) Product Catalog:

3233

Inhibitors & Agonists

20

Fluorescent Dye

9

Biochemical Assay Reagents

3561

Peptides

2

Inhibitory Antibodies

59

Natural
Products

10

Recombinant Proteins

100

Isotope-Labeled Compounds

5

Antibodies

6

Click Chemistry

20

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1811
    Vasopressin
    5+ Cited Publications

    ARGinine vasopressin; Antidiuretic hormone

    		 Endogenous Metabolite Neurological Disease
    Vasopressin is a cyclic nonapeptide that is synthesized centrally in the hypothalamus. Vasopressin participates in the hypothalamic-pituitary-adrenal axis, and regulates pituitary corticotropin secretion by potentiating the stimulatory effects of corticotropin releasing factor. Vasopressin also can act as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors .
    Vasopressin
  • HY-P0049
    Argipressin
    5+ Cited Publications

    ARG8-vasopressin; AVP

    		 Vasopressin Receptor Neurological Disease Cancer
    Argipressin (Arg8-vasopressin) binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a Kd value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1.
    Argipressin
  • HY-P0033
    Argireline
    2 Publications Verification

    Acetyl hexapeptide-3; Acetyl hexapeptide-8

    		 Calcium Channel Neurological Disease
    Argireline (Acetyl hexapeptide-3) is a non-toxic, skin-permeable, antiwrinkle peptide. Argireline significantly inhibits Ca 2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction. Argireline has antiwrinkle and anti-aging activity .
    Argireline
  • HY-12290
    Arg-Gly-Asp-Ser
    5+ Cited Publications

    RGDS peptide; Fibronectin tetrapeptide

    		 Integrin Inflammation/Immunology
    Arg-Gly-Asp-Ser is an integrin binding sequence that inhibits integrin receptor function. Arg-Gly-Asp-Ser directly and specifically bind pro-caspase-8, pro-caspase-9 and pro-caspase-3, while it does not bind pro-caspase-1.
    Arg-Gly-Asp-Ser
  • HY-134434
    Z-Arg-Arg-AMC hydrochloride
    1 Publications Verification

    		 Cathepsin Fluorescent Dye Others
    Z-Arg-Arg-AMC hydrochloride is a highly selective fluorescent Cathepsin B substrate. Z-Arg-Arg-AMC hydrochloride can be hydrolyzed by Cathepsin B to produce a fluorescent product for enzyme activity detection .
    Z-Arg-Arg-AMC hydrochloride
  • HY-P10304
    Cyclo(Arg-Pro)

    Cyclo(Pro-ARG)

    		 Fungal Others
    Cyclo(Arg-Pro) (Cyclo(Pro-Arg)) is an inhibitor for chitinase. Cyclo(Arg-Pro) inhibits cell separation of Saccharomyces cerevisiae, without affecting its growth. Cyclo(Arg-Pro) inhibits the morphological change of Candida albicans from yeast form to filamentous form .
    Cyclo(Arg-Pro)
  • HY-P0133
    (Arg) 9

    Nona-L-ARGinine; Peptide R9

    		 Ser/Thr Protease Neurological Disease
    (Arg)9 (Nona-L-arginine) is a cell-penetrating peptide (CPP) made up of 9 arginine residues, which is an inhibitor of serine endoprotease Furin. (Arg)9 has neuroprotective property, exhibits neuroprotective activity with an IC50 of 0.78 μM in the glutamic acid model .
    (Arg) 9
  • HY-115391
    Boc-LRR-AMC
    1 Publications Verification

    Boc-Leu-ARG-ARG-AMC

    		 Biochemical Assay Reagents Others
    Boc-LRR-AMC (Boc-Leu-Arg-Arg-AMC) is a fluorogenic substrate, which can be utilized for detecting the trypsin-like activity of the 26S proteasome or the 20S proteasome core .
    Boc-LRR-AMC
  • HY-W539944
    Argipressin acetate
    5+ Cited Publications

    ARG8-vasopressin acetate; AVP acetate

    		 Vasopressin Receptor Apoptosis Neurological Disease Cancer
    Argipressin (Arg8-vasopressin) (acetate) binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a Kd value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1 .
    Argipressin acetate
  • HY-P1407
    Z-Val-Arg-Pro-DL-Arg-Fluoromethylketone TFA

    		MALT1 NF-κB MMP Cancer
    Z-Val-Arg-Pro-DL-Arg-Fluoromethylketone TFA is an irreversible MALT1 protein inhibitor. Z-Val-Arg-Pro-DL-Arg-Fluoromethylketone TFA inhibits the growth and invasion of diffuse large B-cell lymphoma by inhibiting MALT1-induced NF-κB activation and MMP expression .
    Z-Val-Arg-Pro-DL-Arg-Fluoromethylketone TFA
  • HY-135070
    Ac-RLR-AMC

    Ac-ARG-Leu-ARG-AMC

    		 Proteasome Others
    Ac-RLR-AMC (Ac-Arg-Leu-Arg-AMC) is a fluorogenic substrate for the 26S proteasome (Ex/Em: 380/440-460 nm). AMC is released upon cleavage, and its fluorescence can be used to quantify the trypsin-like activity of 26S proteasomes .
    Ac-RLR-AMC
  • HY-P0133A
    (Arg)9 TFA
    1 Publications Verification

    Nona-L-ARGinine TFA; Peptide R9 TFA

    		 Ser/Thr Protease Neurological Disease
    (Arg)9 (Nona-L-arginine) TFA is a cell-penetrating peptide (CPP) made up of 9 arginine residues. (Arg)9 TFA has neuroprotective property, exhibits neuroprotective activity with an IC50 of 0.78 μM in the glutamic acid model .
    (Arg)9 TFA
  • HY-112862
    Arg-AMS
    1 Publications Verification

    		 Aminoacyl-tRNA Synthetase Infection
    Arg-AMS (compound 24) is a potent nanomolar inhibitor of arginyl tRNA synthetase, which displays tightly bound inhibitory characteristics for the A-domains in non-ribosomal peptide synthetases (NRPS) enzymes .
    Arg-AMS
  • HY-131618
    Hippuryl-Arg

    Bz-Gly-ARG

    		 Amino Acid Derivatives Others
    Hippuryl-Arg (Bz-Gly-Arg) is a substrate used for fluorescence detection and is commonly used in biochemical studies, especially in studying enzyme activity. The phenylalanine portion of Hippuryl-Arg is connected by an aromatic side chain, which allows it to be detected under ultraviolet light. Hippuryl-Arg is used to detect enzymes that recognize and cut peptide bonds containing arginine .
    Hippuryl-Arg
  • HY-P4270
    Met-Arg-Phe-Ala
    1 Publications Verification

    		 Neprilysin Neurological Disease
    Met-Arg-Phe-Ala is a peptide. Met-Arg-Phe-Ala also is a potent competitive inhibitor for enkephalin-generating endopeptidase (EGE). Met-Arg-Phe-Ala can be used for the research of neurological disease .
    Met-Arg-Phe-Ala
  • HY-114150D
    D-Val-Leu-Arg-pNA acetate

    		Kallikrein Others
    D-Val-Leu-Arg-pNA (acetate) is the acetate form of D-Pro-Phe-Arg-p-nitroanilide (pNa). D-Pro-Phe-Arg-p-nitroanilide (pNa) is the substrate for kallikrein and can be used to assay the activity of kallikrein .
    D-Val-Leu-Arg-pNA acetate
  • HY-P4280
    Arg-Tyr

    H-ARG-Tyr-OH

    		 Reactive Oxygen Species (ROS) Others
    Arg-Tyr is a dipeptide which has strong hydroxyl-radical and hydrogen-peroxide scavenging activity .
    Arg-Tyr
  • HY-P0133B
    (Arg)9 acetate
    1 Publications Verification

    Nona-L-ARGinine acetate; Peptide R9 acetate

    		 Ser/Thr Protease Neurological Disease
    (Arg)9 (Nona-L-arginine) acetate is a cell-penetrating peptide (CPP) made up of 9 arginine residues. (Arg)9 acetate has neuroprotective property, exhibits neuroprotective activity with an IC50 of 0.78 μM in the glutamic acid model .
    (Arg)9 acetate
  • HY-P2500
    (Arg)9, FAM-labeled

    		Fluorescent Dye Others
    (Arg)9, FAM-labeled, a cell-penetrating peptide (CPP), is a nona-arginine (ARG) with FAM label. CPPs have emerged as powerful tools for delivering bioactive cargoes into the cytosol of intact cells .
    (Arg)9, FAM-labeled
  • HY-P4340A
    Arg-Arg-AMC acetate

    		Cathepsin Others
    Arg-Arg-AMC acetate is the acetate salt form of Arg-Arg-AMC (HY-P4340). Arg-Arg-AMC acetate is a fluorescent substrate for cathepsin B and used in the cathepsin B activity assay .
    Arg-Arg-AMC acetate
  • HY-P4548
    Boc-Arg-Val-Arg-Arg-AMC hydrochloride

    Boc-RVRR-AMC

    		 Furin Others
    Boc-Arg-Val-Arg-Arg-AMC hydrochloride (Boc-RVRR-AMC) is a synthetic fluorogenic substrate that is efficiently cleaved by furin .
    Boc-Arg-Val-Arg-Arg-AMC hydrochloride
  • HY-P4500
    Z-Arg-Arg-pNA

    		Cathepsin Others
    Z-Arg-Arg-pNA is a substrate for cathepsin B and can be used to detect this enzyme activity .
    Z-Arg-Arg-pNA
  • HY-P4388
    Z-Arg-Leu-Arg-Gly-Gly-AMC

    		SARS-CoV Infection
    Z-Arg-Leu-Arg-Gly-Gly-AMC is a peptide substrate of SARS-CoV PL pro .
    Z-Arg-Leu-Arg-Gly-Gly-AMC
  • HY-P4554
    H-Phe-Arg-OH

    Phe-ARG

    		 Endogenous Metabolite Metabolic Disease
    H-Phe-Arg-OH is a dipeptide containing phenylalanine and arginine. H-Phe-Arg-OH can be separated from Bradykinin (HY-P0206) through Angiotensin-converting enzyme (ACE, HY-P2983). H-Phe-Arg-OH can be used for metabolic research .
    H-Phe-Arg-OH
  • HY-P4349A
    Pyr-Arg-Thr-Lys-Arg-AMC TFA

    		Thrombin Others
    Pyr-Arg-Thr-Lys-Arg-AMC TFA is a AMC peptide. AMC is a decapeptide that is specifically hydrolyzed by proteases such as trypsin and thrombin. The AMC peptide can be used to determine the activity of protease and the potency of enzyme inhibitors .
    Pyr-Arg-Thr-Lys-Arg-AMC TFA
  • HY-134961
    Z-Ala-Arg-Arg-AMC
    1 Publications Verification

    Fluorogenic Proteasome Substrate; Z-ARR-AMC

    		 Proteasome Others
    Z-Ala-Arg-Arg-AMC (Fluorogenic Proteasome Substrate) is a fluorogenic substrate for assaying trypsin-like activity of proteasome .
    Z-Ala-Arg-Arg-AMC
  • HY-145331A
    ARG1-IN-1 hydrochloride

    		Arginase Cancer
    ARG1-IN-1 (Compound 3) hydrochloride is an orally active arginase inhibitor with an IC50 value of 29 nM. ARG1-IN-1 hydrochloride can inhibit serum arginase activity and increase arginine levels in mouse tumor models. ARG1-IN-1 hydrochloride is applicable for tumor research .
    ARG1-IN-1 hydrochloride
  • HY-P5313A
    Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Tyr acetate

    		Dengue Virus Infection
    Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Tyr acetate is a DEN protease substrate, which can be used in research related to dengue virus (drug development) .
    Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Tyr acetate
  • HY-P10304A
    Cyclo(Arg-Pro) TFA

    Cyclo(Pro-ARG) TFA

    		 Fungal Infection
    Cyclo (Arg-Pro) TFA is a chitinase inhibitor. Cyclo (Arg-Pro) TFA disrupts cell separation and morphological transition of yeast by inhibiting chitinase activity. Cyclo (Arg-Pro) TFA prevents cell separation of Saccharomyces cerevisiae, leading to the formation of grape-like cell clusters, without inhibiting cell growth. Cyclo (Arg-Pro) TFA blocks the morphological transition of Candida albicans from yeast form to hyphal form, without inhibiting cell growth .
    Cyclo(Arg-Pro) TFA
  • HY-P4087
    Cys(Npys)-(Arg)9

    		HIV Infection Cancer
    Cys(Npys)-(Arg)9 is a synthetic cationic cell-penetrating peptide with a reversible thiol-reactive nitropyridyl (Npys) group. Cys(Npys)-(Arg)9 efficiently mediates the internalization and delivery of various "cargo" such as proteins and antibodies by forming reversible disulfide bonds with surface-exposed cysteine residues. Cys(Npys)-(Arg)9 endows TALEN proteins with cell-penetrating activity, enabling gene knockout in mammalian cells and protein transduction in wheat microspores. Cys(Npys)-(Arg)9 can be conjugated with antibodies to form cationized IgG for enhancing endosomal escape of oligonucleotides, or form siRNA delivery complexes. When the molar ratio of Cys(Npys)-(Arg)9 to loaded molecules is higher than 1:1, it exerts certain cytotoxic effects on cells. Cys(Npys)-(Arg)9 can be used in studies related to oral squamous cell carcinoma and HIV infection .
    Cys(Npys)-(Arg)9
  • HY-P4518
    Z-Val-Gly-Arg-pNA

    		Ser/Thr Protease Others
    Z-Val-Gly-Arg-pNA is a chromogenic substrate for urokinase. Z-Val-Gly-Arg-pNA can be used for determination of urokinase activity .
    Z-Val-Gly-Arg-pNA
  • HY-P4253
    Arginyl-Glutamine

    H-ARG-Gln-OH

    		 VEGFR Cardiovascular Disease
    Arginyl-Glutamine is a dipeptide that can decrease VEGF levels and inhibit retinal neovascularization in a mouse model of oxygen-induced retinopathy .
    Arginyl-Glutamine
  • HY-P4323A
    Boc-Gln-Arg-Arg-AMC acetate

    		Fluorescent Dye Others
    Boc-Gln-Arg-Arg-AMC acetate is a fluorogenic substrate for the determination of protease activity. Boc-Gln-Arg-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .
    Boc-Gln-Arg-Arg-AMC acetate
  • HY-158307
    Z-Arg-Arg-βNA acetate

    		Cathepsin Others
    Z-Arg-Arg-βNA acetate is a sensitive dipeptide substrate of the protease Cathepsin B and resistant to proteases H and L. Z-Arg-Arg-βNA acetate can serve as an important tool for distinguishing non-Cathepsin B type proteins .
    Z-Arg-Arg-βNA acetate
  • HY-P4083
    (Arg)9,TAMRA-labeled

    		Fluorescent Dye Others
    (Arg)9,TAMRA-labeled is a TAMRA-labeled cell permeable peptide. (Arg)9 is a cell-permeable peptide used for drug delivery .
    (Arg)9,TAMRA-labeled
  • HY-P4276
    Arg-Trp

    		Bacterial Infection
    Arg-Trp is a dipeptide composed of arginine and tryptophan, and analogues of Arg-Trp-octyl ester show antibacterial activity .
    Arg-Trp
  • HY-P4336
    Dansyl-Ala-Arg

    		Carboxypeptidase Others
    Dansyl-Ala-Arg is a synthetic peptide. Dansyl-Ala-Arg can be used for various biochemical studies .
    Dansyl-Ala-Arg
  • HY-P4522
    Bz-Ala-Arg

    		Biochemical Assay Reagents Others
    Bz-Ala-Arg is a dipeptide. Bz-Ala-Arg is also a substrate of human pancreatic carboxypeptidase B and plasma carboxypeptidase N .
    Bz-Ala-Arg
  • HY-P4117
    Penetratin-Arg

    		Bacterial Inflammation/Immunology
    Penetratin-Arg is an antimicrobial and is used for drug delivery vehicle .
    Penetratin-Arg
  • HY-P4522A
    Bz-Ala-Arg TFA

    		Biochemical Assay Reagents Others
    Bz-Ala-Arg TFA is a dipeptide. Bz-Ala-Arg TFA is also a substrate of human pancreatic carboxypeptidase B and plasma carboxypeptidase N .
    Bz-Ala-Arg TFA
  • HY-D1523
    Z-Arg-Arg-4MβNA triacetate

    		Cathepsin Others
    Z-Arg-Arg-4MβNA triacetate is a cathepsin B-specific substrate and can produce fluorescent end product 4MβNA (λex = 355 nm, λem = 430 nm) .
    Z-Arg-Arg-4MβNA triacetate
  • HY-P0309A
    Arg-Gly-Glu-Ser TFA

    		Integrin Inflammation/Immunology
    Arg-Gly-Glu-Ser TFA is a polypeptide related to RGD and is a negative control for Arg-Gly-Asp-Ser (HY-12290) .
    Arg-Gly-Glu-Ser TFA
  • HY-P4342
    Gly-Arg-AMC

    		Dipeptidyl Peptidase Others
    Gly-Arg-AMC is a peptide substrate of DPAP1 .
    Gly-Arg-AMC
  • HY-RS00908
    ARG2 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    ARG2 Human Pre-designed siRNA Set A contains three designed siRNAs for ARG2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    ARG2 Human Pre-designed siRNA Set A
    ARG2 Human Pre-designed siRNA Set A
  • HY-P5123A
    Arg-Glu(edans)-Ile-His-Pro-Phe-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(dabcyl)-Arg TFA

    		Angiotensin Receptor Others
    Arg-Glu(edans)-Ile-His-Pro-Phe-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(dabcyl)-Ar TFA is a fluorogenic renin substrate  based on the N-terminal tetradecapeptide sequence of human angiotensinogen (hTDP) .
    Arg-Glu(edans)-Ile-His-Pro-Phe-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(dabcyl)-Arg TFA
  • HY-P4087B
    Cys(Npys)-(Arg)9 acetate

    		HIV Others
    Cys(Npys)-(Arg)9 acetate is a synthetic cationic cell-penetrating peptide with a reversible thiol-reactive nitropyridyl (Npys) group. Cys(Npys)-(Arg)9 acetate efficiently mediates the internalization and delivery of various "cargo" such as proteins and antibodies by forming reversible disulfide bonds with surface-exposed cysteine residues. Cys(Npys)-(Arg)9 acetate endows TALEN proteins with cell-penetrating activity, enabling gene knockout in mammalian cells and protein transduction in wheat microspores. Cys(Npys)-(Arg)9 acetate can be conjugated with antibodies to form cationized IgG for enhancing endosomal escape of oligonucleotides, or form siRNA delivery complexes. When the molar ratio of Cys(Npys)-(Arg)9 acetate to loaded molecules is higher than 1:1, it exerts certain cytotoxic effects on cells. Cys(Npys)-(Arg)9 acetate can be used in studies related to oral squamous cell carcinoma and HIV infection .
    Cys(Npys)-(Arg)9 acetate
  • HY-P2673
    Lys-Arg-Thr-Leu-Arg-Arg

    KRTLRR

    		 EGFR Others
    Lys-Arg-Thr-Leu-Arg-Arg (KRTLRR) is a hexapeptide. Lys-Arg-Thr-Leu-Arg-Arg is a substrate of protein kinase C from EGF receptor. Lys-Arg-Thr-Leu-Arg-Arg can be used to determine the activity of protein kinase C .
    Lys-Arg-Thr-Leu-Arg-Arg
  • HY-P4388A
    Z-Arg-Leu-Arg-Gly-Gly-AMC acetate

    		SARS-CoV Infection
    Z-Arg-Leu-Arg-Gly-Gly-AMC acetate is a peptide substrate for SARS-CoV PL pro .
    Z-Arg-Leu-Arg-Gly-Gly-AMC acetate
  • HY-145331
    ARG1-IN-1

    		Arginase Cancer
    ARG1-IN-1 (Compound 3) is an orally active arginase inhibitor with an IC50 value of 29 nM. ARG1-IN-1 can inhibit serum arginase activity and increase arginine levels in mouse tumor models. ARG1-IN-1 is applicable for tumor research .
    ARG1-IN-1
  • HY-135781
    H-Arg(Pbf)-OMe hydrochloride

    		Amino Acid Derivatives Cancer
    H-Arg(Pbf)-OMe hydrochloride is an arginine analogue extracted from patent US20150197500A1, Compound Arg-06 .
    H-Arg(Pbf)-OMe hydrochloride

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