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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
27 Results for "
B lymphocyte proliferation
" in MedChemExpress (MCE) Product Catalog:
Products (27)
27 Results for "B lymphocyte proliferation" in MCE Product Catalog:
14
14 Cited Publications
Cat. No.: HY-B0199A
CAS No.: 116680-01-4
Synonyms: RS 61443 hydrochloride; TM-MMF hydrochloride
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2
2 Cited Publications
Cat. No.: HY-N6939
CAS No.: 82508-31-4
1
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1
1 Cited Publications
Cat. No.: HY-B0199S
CAS No.: 1132748-21-0
Cat. No.: HY-P99568
CAS No.: 2136630-26-5
Synonyms: RC18
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Telitacicept (RC18) is a fully human TACI-Fc fusion protein. Telitacicept is a dual B lymphocyte stimulator (BLyS)/APRIL (a proliferation-inducing ligand) inhibitor that effectively blocks proliferation of B lymphocytes. Telitacicept can be used in research of B-cell autoimmune disease . The component ratio of this product is Active ingredient : Excipients = 1: 0.5-1: 0.8.
Cat. No.: HY-P1827
CAS No.: 219312-69-3
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Cat. No.: HY-B0199R
CAS No.: 128794-94-5
Synonyms: RS 61443 (Standard); TM-MMF (Standard)
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Cat. No.: HY-P10851
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Cat. No.: HY-118917
CAS No.: 297730-05-3
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VX-148 is an orally active immunosuppressant, which is a non-competitive inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitor with Ki values for IMPDH Ⅱ and IMPDH Ⅰ of 6 and 14 nM respectively. VX-148 can significantly inhibit the proliferation of human peripheral blood mononuclear cells (PBMC) stimulated by T-cell mitogen (PHA) or B-cell mitogen (SPAS). VX-148 has high selectivity for lymphocytes (such as L1210, Jurkat T cells, and Raji B cells), but has no significant toxicity to non-lymphoid cells. VX-148 can inhibit antibody responses in mouse models and significantly prolong the survival time of transplanted skin in allogeneic skin transplantation models. VX-148 can be used in the research of autoimmune diseases (such as rheumatoid arthritis, psoriasis) and organ transplantation anti-rejection .
Cat. No.: HY-164670
CAS No.: 2676188-98-8
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D228 is an orally active antiinflammatory agent. D228 reduces ConA induced T lymphocyte cell proliferation (IC50: 42.85 μM) and LPS induced B lymphocyte cell proliferation (IC50: 3.15 μM). D228 is effective against inflammatory bowel disease (IBD). D228 alleviates the DSS (HY-116282C)-induced inflammation response in the IBD model by downregulating the MyD88/TRAF6/p38 signaling .
Cat. No.: HY-P991842
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Cat. No.: HY-B0199AS
Synonyms: RS 61443-d4 hydrochloride; TM-MMF-d4 hydrochloride
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Terpenoids Euphorbia kansui T. N. Liou ex S. B. Ho Diterpenoids Plants Disease Research Fields Inflammation/Immunology Euphorbiaceae Extract
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Cat. No.: HY-N14361
CAS No.: 117568-33-9
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Cat. No.: HY-130757
CAS No.: 571194-06-4
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Cat. No.: HY-118079
CAS No.: 204398-91-4
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Drimentine B is a terpenylated diketopiperazine originally isolated from Actinomycete bacteria that has anticancer activity. It inhibits the proliferation of NS-1 murine β lymphocyte myeloma cells by 41 and 59% in vitro when used at concentrations of 50 and 100 μg/mL, respectively.
Cat. No.: HY-N6939R
CAS No.: 82508-31-4
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Cat. No.: HY-N21625
CAS No.: 713524-97-1
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Flavonoids Monophenols Flavones Phenols Poaceae Extract Pleioblastus amarus(Keng) P. C. Keng Plants
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Cat. No.: HY-N21624
CAS No.: 199925-44-5
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
