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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
39 Results for "
BiP
" in MedChemExpress (MCE) Product Catalog:
Products (39)
39 Results for "BiP" in MCE Product Catalog:
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16 Cited Publications
Cat. No.: HY-P0081
CAS No.: 579492-81-2
Synonyms: BiP-V5; BAX Inhibiting Peptide V5
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7 Cited Publications
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BiP inducer X, a selective inducer of immunoglobulin heavy chain binding protein (BiP)/GRP78, is an effective ER (endoplasmic reticulum) stress inhibitor. BiP inducer X preferentially induces BiP with slight inductions of GRP94, calreticulin, and C/EBP homologous protein. BiP inducer X protects neurons from ER stress .
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Cat. No.: HY-W010838
CAS No.: 205526-38-1
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Cat. No.: HY-W010836
CAS No.: 199110-64-0
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KIRA-7, an imidazopyrazine compound, binds the IRE1α kinase (IC50 of 110 nM) to allosterically inhibit its RNase activity. KIRA-7 has an anti-fibrotic effect .
Cat. No.: HY-N7377
CAS No.: 17851-53-5
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BIP-135 is a potent and selective ATP-competitive GSK-3 inhibitor, with IC50s of 16 nM and 21 nM for GSK-3α and GSK-3β, respectively. BIP 135 exhibits neuroprotective effect .
Cat. No.: HY-P5965
CAS No.: 1421316-16-6
Cat. No.: HY-78843
CAS No.: 147923-08-8
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Cat. No.: HY-RS06432
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HSPA5 Human Pre-designed siRNA Set A contains three designed siRNAs for HSPA5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS06433
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Hspa5 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Hspa5 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-N12656
CAS No.: 477201-98-2
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Cat. No.: HY-125974A
CAS No.: 1082532-95-3
HM03 trihydrochloride is a potent and selective HSPA5 (Heat shock 70kDa protein 5, also known as Bip, Grp78) inhibitor. HM03 trihydrochloride has anticancer activity .
Cat. No.: HY-121459
CAS No.: 22862-63-1
Neoantimycin is a GRP78/BiP and K-Ras regulator with anticancer activity. Its biosynthesis is catalyzed by a hybrid nonribosomal peptide synthetase/polyketide synthase (NRPS/PKS) system .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
