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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
53 Results for "
CCl4
" in MedChemExpress (MCE) Product Catalog:
Products (53)
53 Results for "CCl4" in MCE Product Catalog:
29
Category:
Neurological Disease Umbelliferae Extract Ketones, Aldehydes, Acids Plants Disease Research Fields Endocrinology Echinacea angustifolia DC. Cancer
Target:
6
5
5 Cited Publications
Cat. No.: HY-N0330
CAS No.: 96990-18-0
4
4 Cited Publications
Cat. No.: HY-P7257
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCl4; Act-2; Prev. SCYA4; MIP1B; Prev. LAG1; HC21; MIP-1-Beta; Monocyte Adherence-Induced Protein 5 Alpha; AT744.1; Chemokine C-C Motif Ligand 4; Small Inducible Cytokine A4 (Homologous To Mouse Mip-1b); Small-Inducible Cytokine A4; Macrophage Inflammator
Species:
Human
Source:
E. coli
2
2 Cited Publications
Target:
Research Areas:
XT2 is a potent, orally active, and selective inhibitor of NF-κB-inducing kinase (NIK) with an IC50 of 9.1 nM. XT2 suppresses CCl4-induced upregulation of ALT, a key biomarker of acute liver injury. XT2 also decreases immune cell infiltration into the injured liver tissue. XT2 has the potential for the research of liver inflammatory diseases . XT2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
1
Target:
1
1 Cited Publications
Cat. No.: HY-N0306
CAS No.: 36284-77-2
Category:
Infection Triterpenes Hedera nepalensis K. Koch var. sinensis (Tobl.) Rehd. Terpenoids Plants Disease Research Fields Araliaceae Extract
Target:
1
1
Category:
Cardiovascular Disease Triterpenes Terpenoids Plants Other Families Extract Disease Research Fields
Target:
1
1 Cited Publications
Cat. No.: HY-P71889
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCl4; Act-2; Prev. SCYA4; MIP1B; Prev. LAG1; HC21; MIP-1-Beta; Monocyte Adherence-Induced Protein 5 Alpha; AT744.1; Chemokine C-C Motif Ligand 4; Small Inducible Cytokine A4 (Homologous To Mouse Mip-1b); Small-Inducible Cytokine A4; Macrophage Inflammator
Species:
Mouse
Source:
E. coli
Cat. No.: HY-163897
CAS No.: 3098187-24-4
Research Areas:
PROTAC NCOA4 degrader-1 is a VHL-based PROTAC NCOA4 degrader. PROTAC NCOA4 degrader-1 is a ferroptosis inhibitor. PROTAC NCOA4 degrader-1 reduces Fe 2+ elevation, ROS production, MDA content and PTGS2 mRNA expression. PROTAC NCOA4 degrader-1 ameliorates liver damage in a CCl4-induced acute liver injury model. PROTAC NCOA4 degrader-1 can be used for the researches of inflammation and immunology .
Cat. No.: HY-152293
CAS No.: 1412453-70-3
EVT801 is an orally active and selective inhibitor of VEGFR-3 (IC50=11 nM), which has antitumor effects. EVT801 inhibits not only VEGF-C-induced human endothelial cell proliferation, but also tumor (lymphatic) angiogenesis in tumor mouse models. EVT801 can reduce tumor hypoxia, immunosuppressive cytokines (CCL4, CCL5) and myeloid derived suppressor cells (MDSC) production. EVT801 has synergistic effect with immune checkpoint therapy (ICT), which improves ICT response rate and has better inhibitory effect on cancer mouse models . EVT801 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-152846
CAS No.: 2268739-68-8
Synonyms: GDC-8264
Target:
Research Areas:
Cardiovascular Disease Inflammation/Immunology Endocrinology
Flizasertib (GDC-8264) is an orally active, reversible and selective RIP1 inhibitor with Ki app values of 0.00071 μM and 0.0013 μM for human and cynomolgus monkey RIP1 kinase, respectively. Flizasertib blocks RIP1 autophosphorylation but does not affect RIP1 protein stability. Flizasertib inhibits pro-inflammatory cytokines (CCL3, CCL4, and IL-1β) production. Flizasertib results in inhibition of colitis and ileitis. Flizasertib can be used in the research of cardiac surgery-associated acute kidney injury .
Cat. No.: HY-N7697B
CAS No.: 115350-24-8
Target:
Cat. No.: HY-N7327
CAS No.: 50276-96-5
Target:
Cat. No.: HY-N2358
CAS No.: 118024-26-3
Category:
Flavonoids Flavonones Phenols Polyphenols Plants Compositae Extract Acacia confusa Merr. Disease Research Fields Inflammation/Immunology
Target:
Target:
Cat. No.: HY-RS02102
Target:
Research Areas:
CCL4 Human Pre-designed siRNA Set A contains three designed siRNAs for CCL4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
