Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
59 Results for "
DR5
" in MedChemExpress (MCE) Product Catalog:
Products (59)
59 Results for "DR5" in MCE Product Catalog:
57
Category:
Infection Microorganisms Macrolide Antibiotics Antifungal Antibiotics Mammalian Cell Culture Disease Research Disease Research Fields
Target:
3
Target:
Research Areas:
Cyproterone acetate is an anti-androgen (IC50=7.1 nM) and progestogen synthetic steroid. Cyproterone acetate has affinity with progesteron and with glucocorticoidal receptors .
1
Target:
Research Areas:
Bioymifi (DR5 Activator), a potent TRAIL receptor DR5 activator, binds to the extracellular domain (ECD) of DR5 with a Kd of 1.2 μM. Bioymifi can act as a single agent to induce DR5 clustering and aggregation, leading to apoptosis .
1
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-N1983
CAS No.: 38395-02-7
Cat. No.: HY-P99260
CAS No.: 896731-82-1
Synonyms: AMG 655; TRAIL-R2 mAb; Human Anti-TNFRSF10B Recombinant Antibody
Target:
Research Areas:
Cat. No.: HY-P990715
CAS No.: 2539847-03-3
Synonyms: INBRX-109
Target:
Research Areas:
Cat. No.: HY-P99286
CAS No.: 912628-39-8
Synonyms: PRO 95780; rhuMAb-DR 5; Anti-Human DR5 Recombinant Antibody
Cat. No.: HY-P99270
CAS No.: 918127-53-4
Synonyms: CS-1008; Anti-Human TRAIL-R2 Recombinant Antibody
Cat. No.: HY-P99470
CAS No.: 2109730-69-8
Synonyms: GEN1029
Target:
Research Areas:
Cat. No.: HY-P99299
CAS No.: 845816-02-6
Synonyms: HGS-ETR 2; ETR2-ST01
Cat. No.: HY-P99237
CAS No.: 1615692-28-8
Synonyms: MMUC 1206A
Cat. No.: HY-N7152
CAS No.: 76060-35-0
Category:
Zingiber officinale Roscoe Monophenols Phenols Plants Disease Research Fields Cancer Zingiberaceae
Target:
Cat. No.: HY-P99559
CAS No.: 2109731-10-2
Synonyms: HexaBody-DR5/DR5; Hx-DR5-01/05
Target:
Research Areas:
Cat. No.: HY-P991570
CAS No.: 2378046-35-4
Synonyms: AD5-10; oba-01 Antibody
Synonyms: PGA2; Medullin
Prostaglandin A2 (PGA2) is a Cyclopentenone prostaglandin. Prostaglandin A2 induces Caspase-dependent Apoptosis, activates p53. Prostaglandin A2 activates ERK2 and JNK1/SAPK. Prostaglandin A2 shows antiviral activity against HSV-1. Prostaglandin A2 has anti-tumor effects. Prostaglandin A2 can be used for the research of colorectal cancer, colorectal carcinoma, breast carcinoma, and herpetic keratitis .
P53R3 is a potent p53 reactivator and restores sequence-specific DNA binding of p53 hot spot mutants, including p53 R175H, p53 R248W and p53 R273H. P53R3 induces p53-dependent antiproliferative effects with much higher specificity than PRIMA-1. P53R3 enhances the recruitment of wild-type p53 and p53 M237I to several target gene promoters. P53R3 strongly enhances the mRNA, total protein and cell surface expression of the death receptor death receptor 5 (DR5). P53R3 is used for cancer research .
Cat. No.: HY-N3000
CAS No.: 72401-54-8
Cat. No.: HY-P990249
Target:
Research Areas:
Cat. No.: HY-173025
Target:
Research Areas:
Nurr1 agonist 12 (Compound 37) is the agonist for nuclear receptor-associated protein 1 (Nurr1) that activates the transcriptional activity of Nurr1 with an EC50 of 0.06 μM. Nurr1 agonist 12 activates the human response elements NBRE, NurRE, and DR5 with EC50 of 0.07 μM, 0.027 μM, and 0.014 μM, respectively. Nurr1 agonist 12 induces the expression of Nurr1-regulated neurotrophic genes, such as tyrosine hydroxylase (TH), SOD1/2, BDNF, Sestrin 3, and BIRC5 (Survivin). Nurr1 agonist 12 exhibits neuroprotective efficacy against Paraquat-induced neurotoxicity .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
