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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
58 Results for "
EST
" in MedChemExpress (MCE) Product Catalog:
Products (58)
58 Results for "EST" in MCE Product Catalog:
Research Areas:
Adenosine 3',5'-diphosphate disodium is an endogenous purine nucleotide. Adenosine 3',5'-diphosphate disodium acts as an inhibitor of bovine adrenal estrogen sulfotransferase (EST) with a Ki value of 7.0 μM. It also serves as an indispensable specific cofactor for the pregnenolone-binding protein (PBP) steroid-binding complex, with an EC50 value of 1.5 μM in guinea pigs .
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EST64454 hydrochloride is a selective and orally active sigma-1 receptor antagonist with a Ki of 22 nM. EST64454 hydrochloride has the potential for the research of the pain .
Cat. No.: HY-131914
CAS No.: 1351438-26-0
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EST64454 (compound 9k) is a selective, orally active sigma-1 receptor antagonist with Ki 22 nM. EST64454 can be used to study pain .
Cat. No.: HY-131914B
CAS No.: 2088272-67-5
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EST64454 maleate is a highly soluble σ1 receptor antagonist, demonstrating potent antinociceptive properties for pain treatment. EST64454 maleate exhibits excellent metabolic stability across various species and possesses an adequate pharmacokinetic profile in rodents. EST64454 maleate has been identified as a promising clinical candidate due to its favorable aqueous solubility and high permeability in Caco-2 cells.
Cat. No.: HY-134189
CAS No.: 1838622-25-5
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EST73502 is a selective, orally active and blood-brain barrier (BBB) penetrant dual μ-opioid receptor (MOR) agonist and σ1 receptor (σ1R) antagonist, with Kis of 64 nM and 118 nM for MOR and σ1R, respectively. EST73502 has antinociceptive activity .
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EST73502 monohydrochloride is a selective, orally active and blood-brain barrier (BBB) penetrant dual μ-opioid receptor (MOR) agonist and σ1 receptor (σ1R) antagonist, with Kis of 64 nM and 118 nM for MOR and σ1R, respectively. EST73502 monohydrochloride has antinociceptive activity .
Cat. No.: HY-RS18107
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Sult1e1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sult1e1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14019
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Research Areas:
SULT1E1 Human Pre-designed siRNA Set A contains three designed siRNAs for SULT1E1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS08067
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Map3k8 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Map3k8 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS08066
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MAP3K8 Human Pre-designed siRNA Set A contains three designed siRNAs for MAP3K8 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-187458
CAS No.: 3105892-11-0
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EST1140 is a covalent molecular glue degrader targeting RNF126 for AR/AR-V7, with DC50 values of 33 μM and 30 μM, respectively, in 22Rv1 cells. EST1140 covalently binds to the E3 ligase RNF126 to achieve targeted protein degradation. EST1140 can be used in the research of androgen-independent prostate cancer .
Cat. No.: HY-P701854
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PMF1; EST1p-Like Protein B (EST1B); Polyamine Modulated Factor 1; PMF-1; Polyamine-Modulated Factor 1
Species:
Human
Source:
E. coli
Cat. No.: HY-P703519
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Cutinase EST1; EC:3.1.1.74; Poly(ethylene terephthalate) hydrolase; PET hydrolase; PETase; EC:3.1.1.101; EST1
Species:
Others
Source:
E. coli
Cat. No.: HY-P701855
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PMF1; EST1p-Like Protein B (EST1B); Polyamine Modulated Factor 1; PMF-1; Polyamine-Modulated Factor 1
Species:
Human
Source:
E. coli
Cat. No.: HY-P81421A
Synonyms: MRP4; MOATB; MOAT-B; EST170205
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
